The Role of Diaphragmatic Myofascial Release in Reducing Abdominal Pain in a Patient with Shoulder Pain: A Case-Based Perspective

Case Report | DOI: https://doi.org/10.31579/2690-4861/852

The Role of Diaphragmatic Myofascial Release in Reducing Abdominal Pain in a Patient with Shoulder Pain: A Case-Based Perspective

  • Fateme Ghaderi Varkani 2
  • Khadijeh Otadi 1*
  • Siamak Bashardoost Tajali 1
  • Kazem Malmir 1

1Associate Professor in the Department of Physiotherapy at Tehran University of Medical Sciences (TUMS) in Tehran, Iran.

2MSc student of Physiotherapy in Tehran University of Medical Sciences.

*Corresponding Author: Khadijeh Otadi, Associate Professor in the Department of Physiotherapy at Tehran University of Medical Sciences (TUMS) in Tehran, Iran.

Citation: Fateme G. Varkani, Khadijeh Otadi, Siamak B. Tajali, Kazem Malmir, (2025), The Role of Diaphragmatic Myofascial Release in Reducing Abdominal Pain in a Patient with Shoulder Pain: A Case-Based Perspective, International Journal of Clinical Case Reports and Reviews, 26(5); DOI:10.31579/2690-4861/852

Copyright: © 2025, Khadijeh Otadi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 15 May 2025 | Accepted: 29 May 2025 | Published: 19 June 2025

Keywords: diaphragmatic release; visceral pain; appendectomy; myofascial therapy; abdominal pain

Abstract

Postoperative abdominal and visceral pain is a common complication in patients following appendectomy, especially when associated with peritonitis. The diaphragm, as the primary respiratory muscle innervated by the phrenic nerve (C3–C5), has extensive anatomical and functional relationships with thoracoabdominal and pelvic structures. Fascial restrictions or dysfunction in diaphragmatic movement may contribute to increased intra-abdominal tension and altered visceral mobility, thereby intensifying pain in the abdominal and pelvic regions. This case report presents a 45-year-old female patient who developed persistent abdominal and right thigh pain following an appendectomy complicated by peritonitis. The patient also suffered from right shoulder pain and was referred to physiotherapy for treatment of shoulder pain. In addition to standard physiotherapy, six sessions of diaphragmatic myofascial release were administered.

Outcome’s measure was Pain that assessed using the Visual Analog Scale (VAS), chest expansion by tape measure, the Shoulder Pain and Disability Index by SPADI, and the satisfaction by SF-12 quality of life questionnaire. After six sessions treatment consists of diaphragmatic release besides of conventional treatment on shoulder, the patient reported a 90% reduction in visceral pain in the abdominal and inguinal areas. Chest expansion increased from 1.6 cm to 3.5 cm, and the SPADI score improved from 40 to 25. These findings suggest that restoring diaphragmatic mobility through myofascial release can significantly alleviate postoperative abdominal and referred pain, likely by reducing fascial tension and improving neurovisceral dynamics.

Introduction

Shoulder pain is the third most common musculoskeletal complaint worldwide, with a prevalence reaching up to 67% in some populations [1]. In many cases, this pain is attributed to localized biomechanical dysfunction; however, emerging evidence highlights the role of remote influences, such as visceral and fascial dysfunctions, in contributing to shoulder symptoms. The diaphragm is the primary muscle of respiration, innervated by the phrenic nerve (C3–C5), and shares close neurological and fascial connections with the brachial plexus and muscles of the shoulder girdle. Dysfunction of the diaphragm—whether due to restricted mobility, fascial adhesions, or post-surgical complications—may alter breathing patterns and increase recruitment of accessory respiratory muscles. Several of these muscles directly influence shoulder mechanics, and their overactivation may disrupt the scapulohumeral rhythm and contribute to pain [2,3].

Following abdominal surgery such as appendectomy, patients may develop fascial adhesions, peritoneal irritation, or diaphragmatic restrictions, especially in the presence of complications like peritonitis. Studies indicate that up to 93% of abdominal surgeries result in adhesions, which can provoke chronic or referred pain by altering local and systemic neuromyofascial dynamics [4]. These adhesions and fascial tensions can trigger aberrant afferent input, increased sympathetic tone, and protective postural responses that further reinforce pain cycles [5,6]. In such scenarios, pain is often not limited to the abdominal region but may manifest in more distant structures, including the shoulder.

The myofascial system, rich in mechanoreceptors such as Golgi, Ruffini, and Pacinian corpuscles, plays a crucial role in proprioception and pain perception. Fascial restrictions or scars following surgery can create a state of sustained tension, potentially affecting movement patterns, visceral function, and somatic structures [7]. According to the regional interdependence model, dysfunction in one area—such as the diaphragm—can result in compensatory adaptations and symptoms in distant but functionally connected areas [8]. According to studies, approximately 93% of abdominal surgeries lead to adhesions and chronic or sometimes referred pain.

Sometimes, these adhesions arise from chronic inflammation or infection. Adhesions increase tension and impair deep sensory input in the area, resulting in abnormal output and various consequences such as disturbed protective reflexes, increased autonomic activity, and pain syndromes (Kobesova et al., Valouchova, Lewit) [9]. Various techniques such as massage, myofascial release, and soft tissue mobilization are used to restore the elasticity of the skin near the scar and the underlying soft tissue layers that are affected by the scar and adhesion. Previous studies have shown positive results from soft tissue mobilization in relieving abdominal adhesions and pain, which improve function. For example, abdominal scars may cause pain in the lower back, shoulder, and more distant areas of the body. As a case study, Kobesova and colleagues reported the benefits of manual scar tissue mobilization in a 20-year-old woman with abdominal pain, low back pain, pelvic floor dysfunction, and constipation symptoms [10].

This case report presents the clinical course of a 45-year-old woman who developed chronic right shoulder pain after undergoing an appendectomy complicated by peritonitis. Despite receiving physiotherapy for shoulder pain, her visceral and abdominal pain persisted. A targeted diaphragmatic myofascial release approach was integrated into her rehabilitation plan. The outcomes suggest a meaningful reduction in both visceral and shoulder symptoms, emphasizing the relevance of assessing and addressing diaphragmatic function in patients presenting with complex post-surgical pain syndromes.

Case Presentation

A 45-year-old married woman with one child and employed as an office administrator presented to the outpatient physiotherapy clinic with a primary complaint of chronic right anterior shoulder pain persisting for approximately one year. The pain was localized to the acromial region and lateral aspect of the deltoid, described as dull and activity-dependent. The pain was aggravated by overhead movements and routine work-related tasks.

Clinical Assessment:

Resisted abduction and mid- arc elevation reported with discomfort and pain without significant restriction in active range of motion. During detailed history-taking, the patient revealed undergoing an appendectomy one year prior due to acute appendicitis, which had been complicated by delayed diagnosis, bowel perforation, and generalized peritonitis. Following recovery, she began experiencing persistent discomfort in the abdominal region, particularly in the right lower quadrant, periumbilical zone, suprapubic region, right inguinal area, and anterior thigh. These symptoms coexisted with the onset of right shoulder pain. Based on the chronicity of her symptoms and the distribution of pain—including signs suggestive of visceral-somatic interaction—the treating physiotherapist suspected potential diaphragmatic involvement through fascial continuity, visceral adhesions, or postural compensations following surgery. The therapeutic plan was designed to include both conventional physiotherapy for shoulder pain and diaphragmatic myofascial release to address possible remote contributors.

Intervention

The patient received a total of six treatment sessions over two weeks (three sessions per week, every other day). The treatment protocol consisted of two integrated approaches:

1. Routine Physiotherapy for Shoulder pain consist of Low-frequency TENS (<10>

2. Diaphragmatic Myofascial Release (MFR)

After performing routine physiotherapy interventions, two techniques were used for myofascial diaphragm muscle release. As shown in Figure 1, in the first technique, the patient was in a supine position, the limbs were in a relaxed state, and the therapist stood at the head of the patient. In this position, the therapist's forearms were aligned with the patient’s shoulders, and the therapist made contact with the hypochondriac regions using the inner three fingers while positioning them under the costal cartilages of ribs 7 to 10 bilaterally. While synchronizing with the patient’s breathing, the therapist applied a gentle upward (elevation) and slightly outward force on the patient’s rib cage in coordination with the patient’s inhalation, resisting rib motion. This technique was performed in 2 sets of 10 repetitions, with deep breathing and intervals of 1 minute between sets. [13]

                                                                            

                                                                                                Figure 1: first and second method of diaphragm release

In the second technique (Figure 2), the patient lay in the prone position. One of the therapist’s hands was placed on the posterior ends of the ribs and the other hand on the patient’s abdomen. The therapist then rotated the patient's body slightly from side to side to mobilize the polyaxially 

region. The therapist repeated this motion in a circular pattern, with each hand moving in opposite directions. Each cycle took one minute per side. This technique was also applied for the diaphragm in the same number of 

sets. The total duration of the diaphragm release and treatment session for each patient was about 8 minutes. [14]

The combined treatment protocol (routine physiotherapy plus diaphragmatic MFR) was conducted over six sessions on alternate days. Outcome variables measured before and after treatment are reported in Table 1.

Assessments

                                                                                                    

Figure 2: presents the timeline of assessments and interventions in general. The assessments were conducted at baseline (T0), immediately following treatment (T1)

Pain

Pain intensity measured by Visual Analogue Scale (VAS) during daily occupational activities and at rest. The Visual Analogue Scale (VAS) is a widely used, validated tool for assessing the intensity of pain. It typically consists of a horizontal 10-centimeter line, with the endpoints labeled as "no pain" (0) on the left and "worst imaginable pain" (10) on the right. Patients are asked to mark a point on the line that corresponds to the intensity of their perceived pain. The distance from the "no pain" anchor to the patient's mark is measured in centimeters and recorded as their pain score. The VAS is simple, sensitive to changes over time, and useful for both clinical assessment and research purposes.

Chest Expansion Measurement (Circumferential Thoracic Excursion) is a simple and non-invasive clinical method used to assess the mobility of the thoracic cage during respiration. It reflects the function of respiratory muscles—especially the diaphragm—and the compliance of the thoracic wall and lungs. Using a tape measure, chest circumference is measured at a standardized level (commonly at the level of the 4th intercostal space in males or just below the breast in females) during maximal inspiration and expiration. The difference between these two measurements indicates the chest expansion.

The Shoulder Pain and Disability Index (SPADI) is a self-reported questionnaire specifically designed to measure the pain and functional disability associated with shoulder pathology. The SPADI consists of 13 items divided into two subscales: 1. Pain Subscale (5 items): Assesses the intensity of shoulder pain during various activities. 2.Disability Subscale (8 items): Evaluates the degree of difficulty in performing everyday tasks that require shoulder use. Each item is scored on a visual analogue scale (VAS) or a numeric scale from 0 (no pain/difficulty) to 10 (worst imaginable pain/difficulty). The total score is calculated as a percentage, with higher scores indicating greater pain and disability.

The 12-Item Short Form Health Survey (SF-12) is a brief, validated questionnaire used to assess health-related quality of life across both physical and mental domains.

SF-12 is a condensed version of the SF-36 and includes 12 questions that cover 8 health dimensions:

  • Physical functioning
  • Role limitations due to physical health
  • Bodily pain
  • General health perceptions
  • Vitality (energy/fatigue)
  • Social functioning
  • Role limitations due to emotional problems
  • Mental health

From these, two key composite scores are derived:

  • 1. Physical Component Summary (PCS-12)

Reflects physical health status, including physical functioning and pain.

  • 2. Mental Component Summary (MCS-12)

Reflects mental well-being, including emotional and social functioning.

Both scores are standardized (mean = 50, SD = 10 in the general population), with higher scores indicating better health status. (MCS-12)

Outcome VariableBefore TreatmentAfter Treatment
VAS during daily work activities54
VAS at rest30
Chest expansion (cm)1.63.5
SPADI score (pain and disability)4025
Quality of life – Physical Component (PCS-12)36.1353.09
Quality of life – Mental Component (MCS-12)34.9639.96

                                                                               Table 2: Changes in Outcome Variables Before and After Intervention

Results

Following six sessions of combined routine physiotherapy and diaphragmatic myofascial release. Pain intensity decreased during daily activities and completely resolved at rest. Chest expansion improved substantially, disability related to shoulder function reduced, and both physical and mental components of quality of life improved. Importantly, the patient reported approximately a 90% reduction in chronic abdominal pain in the right lower quadrant, umbilical, suprapubic, inguinal, and anterior thigh regions—pain that had persisted since the appendectomy. This reduction remained stable six months after treatment completion. It should be noted that no specific visceral pain assessments were performed prior to treatment as the patient’s primary complaint was shoulder pain.

Discussion

In this case, myofascial release of the diaphragm in a patient suffering chronic abdominal pain after appendectomy, alongside shoulder pain, resulted in reduced abdominal and shoulder pain, increased chest expansion, decreased disability, and improved quality of life. The undeniable relationship between the respiratory system and the shoulder joint [14] suggests that the observed improvements may be attributed to the myofascial release of the diaphragm combined with routine physiotherapy. Fascial continuity, neurological connections between the diaphragm and shoulder muscles, and the anatomical-functional relationship between respiratory muscles and shoulder structures may explain the involvement of the shoulder following diaphragmatic dysfunction after abdominal surgery [15]. However, as both routine physiotherapy and diaphragmatic myofascial release were applied simultaneously, it is difficult to isolate the specific contribution of each treatment to the overall improvement.

Nevertheless, increased chest expansion and reduced visceral pain are likely attributable to the release of the diaphragmatic fascia. These findings align with previous studies demonstrating significant improvements in chest wall mobility following diaphragmatic manual therapy. Additionally, the visceral pain relief following manual diaphragm treatment supports the role of fascial release in managing post-surgical adhesions and related symptoms. Since this is a single-case report, further research with larger sample sizes is needed to generalize the effectiveness of these interventions. Given the absence of reported side effects from diaphragmatic myofascial release, and its low cost and non-reliance on special equipment, this technique may be recommended as a complementary approach by other clinicians.

Conclusion

Based on the findings of this case report, diaphragmatic myofascial release appears to be an effective adjunctive treatment for improving shoulder symptoms and chronic abdominal pain following abdominal surgery.

Acknowledgments

The authors sincerely thank the patient who participated in this study. There are no conflicts of interest among the authors.

References

Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.

img

Virginia E. Koenig

Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.

img

Delcio G Silva Junior

Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.

img

Ziemlé Clément Méda

Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.

img

Mina Sherif Soliman Georgy

We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.

img

Layla Shojaie

The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.

img

Sing-yung Wu

Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.

img

Orlando Villarreal

Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.

img

Katarzyna Byczkowska

Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.

img

Anthony Kodzo-Grey Venyo

Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.

img

Pedro Marques Gomes

Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.

img

Bernard Terkimbi Utoo

This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.

img

Prof Sherif W Mansour

Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.

img

Hao Jiang

As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.

img

Dr Shiming Tang

Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.

img

Raed Mualem

International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.

img

Andreas Filippaios

Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.

img

Dr Suramya Dhamija

Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.

img

Bruno Chauffert

I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

img

Baheci Selen

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

img

Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

img

Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

img

Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

img

Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

img

Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

img

S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

img

Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

img

George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

img

Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

img

Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

img

Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

img

Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

img

Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

img

Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

img

Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

img

Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

img

Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

img

Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

img

Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

img

Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

img

Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

img

Zhao Jia

Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."

img

Thomas Urban

I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.

img

Cristina Berriozabal

To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.

img

Dr Tewodros Kassahun Tarekegn

"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".

img

Dr Shweta Tiwari

I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.

img

Dr Farooq Wandroo

Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.

img

Dr Anyuta Ivanova

We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.

img

Dr David Vinyes

My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.

img

Gertraud Teuchert-Noodt

To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina

img

Dr Elvira Farina

Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.

img

Dr Oleg Golyanovski

Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.

img

Dr Susan Anne Smith

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.

img

Dr Farahnaz Fallahian

Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.

img

Dr Victor Olagundoye

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.

img

Dr Susan Anne Smith

Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD

img

Dr Eric S Nussbaum

Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.

img

Hala Al Shaikh

Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.

img

Dr Rakhi Mishra