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Research Article | DOI: https://doi.org/10.31579/2641-0419/489
1University of Abuja Teaching Hospital, Gwagwalada, FCT, Abuja.
2Veritas University Abuja.
3Nisa-Garki, Abuja.
4Univerity of Ilorin Teaching Hospital, Ilorin.
5Nnamdi Azikwe University Teaching Hospital, Nnewi.
*Corresponding Author: Ibikunle Moses Durotoluwa, Veritas University Abuja.
Citation: Ibikunle M. Durotoluwa, Ezinne I. Madubuonu, Chetachukwu I. Enendu, Maryam A. Abdullahi, Gabriel A. Adikwu, et al. (2025), Impact of Combined Hypertension and Diabetes on Dyslipidemia Prevalence Among Adults Aged 60 and Older: A retrospective study, J Clinical Cardiology and Cardiovascular Interventions, 8(11); DOI:10.31579/2641-0419/489
Copyright: © 2025, Ibikunle Moses Durotoluwa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 17 June 2025 | Accepted: 16 July 2025 | Published: 25 July 2025
Keywords: dyslipidemia; diabetes; hypertension; cardiovascular risk; older adults; lipid profile; cross-sectional study
Background and Aim: Dyslipidemia is a major modifiable risk factor for cardiovascular disease, particularly among older adults. Comorbidities such as diabetes mellitus and hypertension may exacerbate lipid abnormalities, compounding cardiovascular risk. This study aims to assess the impact of these comorbidities on lipid profiles among adults aged 60 years and above using a cross-sectional approach.
Method and Materials: A retrospective study was conducted on 579 participants aged 60 and above. Dyslipidemia was defined based on established lipid profile thresholds, including elevated total cholesterol (.>5.2 mmol/L), LDL-C (>3.4 mmol/L), triglycerides (≥1.7 mmol/L), or low HDL-C (<1.0 mmol/L in males and <1.3 mmol/L in females). Descriptive statistics were computed by gender to compare dyslipidemia prevalence and lipid profile characteristics.
Results: The prevalence of dyslipidemia was higher among females (60.2%) compared to males (44.6%). Gender differences in lipid profiles were evident, with females having higher levels of total cholesterol (5.19 mmol/L vs. 4.67 mmol/L) and LDL cholesterol (3.18 mmol/L vs. 2.84 mmol/L), while males exhibited higher HDL cholesterol (1.69 mmol/L vs. 1.38 mmol/L) and lower triglyceride levels (1.23 mmol/L vs. 1.48 mmol/L). Additionally, individuals with multiple comorbidities had the highest prevalence of dyslipidemia (65.8%), followed by those with no comorbidities (53.9%) and single comorbidities (44.9%). Hypertension was associated with lower total cholesterol and LDL cholesterol, but higher HDL cholesterol compared to non-hypertensive individuals, while diabetes showed no significant impact on lipid profiles compared to non-diabetics. Statin users had significantly higher total cholesterol, LDL-C, and cardiovascular risk scores, but lower HDL-C levels. Increasing age (OR = 1.030, 95% CI: 1.005-1.055, p = 0.018) was significantly associated with the increased odds of dyslipidemia, whereas hypertension, diabetes, statin use, and gender were not significant factors.
Conclusion: Older adult females exhibit a higher prevalence of dyslipidemia and less favorable lipid profiles compared to their male counterparts. These findings underscore the need for gender-specific screening and interventions in dyslipidemia management among the elderly.
As the global population continues to age, the occurrence of multiple comorbidities in older adults has significantly increased. Dyslipidemia, which is marked by abnormal lipid levels such as high total cholesterol, elevated low-density lipoprotein (LDL) cholesterol, reduced high-density lipoprotein (HDL) cholesterol, and high triglycerides, is a prevalent metabolic disorder in this demographic.[1] The presence of comorbid conditions, including diabetes, hypertension, cardiovascular diseases, and obesity, has been found to profoundly impact lipid metabolism and heighten the risk of developing dyslipidemia in older adult.[2,3]
Dyslipidemia is widespread across all geopolitical zones of Nigeria, with prevalence rates ranging from 60% among healthy individuals to as high as 89% among diabetic patients.[4] In older populations, the prevalence of dyslipidemia is notably high, with patterns varying depending on the presence of comorbid conditions. Low HDL cholesterol (HDL-C) is the most common dyslipidemia pattern, affecting 37.6% to 59.3% of individuals.[3] Elevated LDL cholesterol (LDL-C) is observed in 25.7% to 60.9% of individuals, particularly among those with diabetes or hypertension.[4] Hypertriglyceridemia (high TG) is found in 15% to 34.8% of individuals, often associated with obesity and diabetes. [5]Additionally, studies suggest regional differences in dyslipidemia prevalence between rural and urban populations: rural dwellers tend to have higher rates of elevated LDL-C and hypertriglyceridemia, likely due to lifestyle factors such as lower physical activity levels and poor dietary habits.[4]
Comorbidities such as diabetes, hypertension, cardiovascular diseases, obesity, chronic kidney disease (CKD), and thyroid disorders significantly contribute to the development of dyslipidemia in older adults. These conditions often interact with each other, amplifying the risk of dyslipidemia and its associated cardiovascular complications.[6] Diabetes is strongly linked to dyslipidemia, particularly elevated triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C 4,5] A study revealed that diabetic individuals aged 60 and older had a notably higher prevalence of dyslipidemia compared to their non-diabetic counterparts in the same age group. [7-8]The altered lipid profile in diabetes is thought to play a key role in the increased cardiovascular risk observed in this patients.[7, 8]
Hypertension, another common comorbidity in older adults, is closely associated with dyslipidemia. Both conditions frequently coexist due to age-related mechanisms, including endothelial dysfunction and increased arterial stiffness. In elderly individuals, hypertension can lead to elevated LDL cholesterol and triglycerides while simultaneously lowering HDL cholesterol levels.[9,10] Studies also demonstrated that hypertensive patients aged 60 and above had significantly higher levels of total cholesterol and LDL cholesterol compared to normotensive individuals. The combination of high blood pressure and dyslipidemia accelerates atherosclerosis, increasing the risk of cardiovascular events in this population.[11, 12]
Older adults with pre-existing cardiovascular diseases (CVD), such as coronary artery disease or heart failure, often exhibit dyslipidemia as part of their disease process. Dyslipidemia in individuals with CVD is typically characterized by high LDL cholesterol and triglyceride levels, and low HDL cholesterol.[2]People with heart disease are more likely to have lipid imbalances that contribute to plaque formation in the arteries, elevating the risk of myocardial infarction and stroke. [12, 13]The relationship between CVD and dyslipidemia is complex, involving genetic, inflammatory, and metabolic factors. Additionally, older adults with CVD are often prescribed statins or other lipid-lowering drugs, which can alter their lipid profiles and affect the relationship between CVD and dyslipidemia.[14, 15]
Obesity, particularly visceral obesity, is closely associated with dyslipidemia in older adults. The accumulation of excess adipose tissue leads to an increase in free fatty acid production, which disrupts lipid metabolism by raising triglyceride levels and lowering HDL cholesterol. [16, 17] Studies reviewed older adults with obesity were at a significantly higher risk of developing dyslipidemia, even after accounting for comorbidities like diabetes and hypertension. Furthermore, obesity is often linked to insulin resistance in older adults, which exacerbates dyslipidemia by increasing triglycerides and decreasing HDL cholesterol levels. The combination of obesity and comorbidities like diabetes further elevates the cardiovascular risks associated with dyslipidemia.[2,18,19]
Chronic kidney disease (CKD) is another common comorbidity in older adults that is frequently associated with dyslipidemia. CKD leads to alterations in lipid metabolism, often resulting in elevated triglyceride levels, increased LDL cholesterol, and decreased HDL cholesterol. Studies have shown that dyslipidemia in CKD patients contributes to the accelerated progression of atherosclerosis, increasing the risk of cardiovascular morbidity and mortality.[20, 21] In the general population, CKD is strongly associated with an unfavorable lipid profile, characterized by elevated triglycerides and a higher concentration of small, dense LDL particles, which are considered more atherogenic. The interplay between renal dysfunction, dyslipidemia, and cardiovascular disease is a critical concern for older adults with CKD.[20, 21]
Thyroid dysfunction, especially hypothyroidism, is prevalent in older adults and can significantly impact lipid metabolism. Hypothyroidism is typically associated with elevated total cholesterol and LDL cholesterol levels, while hyperthyroidism generally lowers cholesterol levels.[22-24] A study found that older adults with subclinical hypothyroidism had a higher incidence of dyslipidemia, primarily elevated LDL cholesterol levels. The effects of thyroid dysfunction on lipid metabolism may be further exacerbated by the presence of other comorbidities such as diabetes and hypertension, making the management of lipid levels more challenging in this population.The relationship between comorbidities and dyslipidemia in older adults is complex and involves several key mechanisms, including insulin resistance, endothelial dysfunction, and inflammation.[25-27]
While individual comorbidities such as diabetes, hypertension, and obesity have been associated with dyslipidemia, there is limited research that systematically examines the combined effect of multiple comorbidities on dyslipidemia in older adults. Additionally, although the relationship between dyslipidemia and cardiovascular risk is well-established, the impact of the cumulative burden of multiple comorbidities on cardiovascular risk through dyslipidemia in older adults remains insufficiently understood.[6, 28] Therefore, this study aims to explore the relationship between specific comorbidities (diabetes, hypertension, cardiovascular diseases) and dyslipidemia in adults aged 60 and above. It will assess the prevalence of dyslipidemia in older adults with different comorbidities and investigate whether the presence of multiple comorbidities increases the risk of dyslipidemia more than a single comorbidity. The study will offer valuable insights into whether multiple comorbidities amplify the risk of dyslipidemia, as compared to the effect of each comorbidity individually, and evaluate the overall cardiovascular risk in older adults.
Data Source:
Definition of Term; For the purpose of this study, dyslipidemia was defined using guidelines from National Cholesterol Education Program (NCEP ATP III): [29-31]
Data Management
Ethical clearance was obtained from Federal Capital Territory Health Research Ethical Review Committee. The study adhered to ethical guidelines, ensuring patient confidentiality and privacy. The collected data were processed and analyzed using statistical software MS-Excel 2013 and SPSS version 24. First data was entered in excel and then transferred to SPSS for analysis.
Statistical analysis was performed with SPSS software version 24. Data was expressed as the mean ± SD for continuous variables while categorical variables were expressed as frequencies and percentages. Categorical variables were compared with chi-square while means was compared using independent t test between 2 groups. Of more than 2 groups and with a continuous outcome was tested with one way analysis of variance ANOVA. Association between variables was determined using Pearson’s or Spearman’s coefficient of association if the data was normally distributed or skewed respectively. Multiple logistic regression was used to determine the association between multiple variables. Significant P value was taken to be Less-than sign 0.05
The study cohort consists of older adults, with a mean age of 67.6 years, ranging from 60 to 92 years. The average age was comparable between genders, with females having a mean age of 68.5 years and males 67.6 years. A significant proportion of participants are hypertensive (82.47 Percentage), and many also have diabetes (64.18 Percentage). Statin use is prevalent, with 55.93Percentage of participants being prescribed statins. Table1
Dyslipidemia was more common among females, with 60.2 Percentage of females affected compared to 44.6 Percentage of males. Gender differences in lipid profiles were observed, with females exhibiting higher mean levels of total cholesterol (5.19 mmol/L vs. 4.67 mmol/L) and LDL cholesterol (3.18 mmol/L vs. 2.84 mmol/L), while males had higher HDL cholesterol levels (1.69 mmol/L vs. 1.38 mmol/L) and lower triglyceride levels (1.23 mmol/L vs. 1.48 mmol/L)-Table 1. A higher prevalence of elevated total cholesterol (TC) was noted in females (15.3 Percentage higher than males), while males had a higher prevalence of elevated triglycerides (3.4 Percentage higher than females). Additionally, low HDL cholesterol (HDL-C) was more common in males (22.0 Percentage vs. 18.6 Percentage) (Table 2).
The prevalence of dyslipidemia varied across different comorbidity groups. Participants with multiple comorbidities exhibited the highest prevalence of dyslipidemia (65.8 Percentage), followed by those without comorbidities (53.9 Percentage), and those with a single comorbidity (44.9 Percentage) - (Table 3). Hypertensive individuals had significantly lower levels of total cholesterol and LDL cholesterol, but higher levels of HDL cholesterol compared to their non-hypertensive counterparts. No significant differences in lipid levels or cardiovascular risk scores were found between diabetic and non-diabetic individuals.
Statin users displayed significantly different lipid profiles and cardiovascular risk scores compared to non-users. Statin use was associated with significantly higher levels of total cholesterol, LDL-C, and cardiovascular risk scores, but lower levels of HDL-C, when compared to non-users (Tables 4a-c).
Multivariate logistic regression analysis was conducted to determine the independent effects of various risk factors on the likelihood of dyslipidemia in older adults. After adjusting for age, the only factor significantly associated with an increased odds of dyslipidemia was age itself (Odds Ratio = 1.030, 95 Percentage Confidence Interval: 1.005 - 1.055, p = 0.018). Neither hypertension, diabetes, statin use, nor gender showed a significant association with dyslipidemia in this model.
| Variable | N= 579 Mean | Female n= 294 | Male n =285 |
| Age | 67.56 ± 6.79 | 68.5 ± 7.1 | 67.6 ± 7.5 |
| Total Cholesterol (mmol/L) | 4.94 ± 1.24 | 5.19 ± 1.2 | 4.64 ± 1.1 |
| LDL-C (mmol/L) | 3.04±1.13 | 3.18±1.1 | 2.84±0.9 |
| HDL-C (mmol/L) | 1.32±0.45 | 1.38±0.5 | 1.69±0.4 |
| Triglyceride (mmol/L) | 1.52±3.08 | 1.48±0.6 | 1.23±0.7 |
| Systolic BP (mmHg) | 134.43 ±3.08 | 136.7± 20.8 | 133.0±25.6 |
| CV score % | 20.89 ± 13.12 | 16.9±8.6 | 25.7± 16.5 |
| Dyslipidemia n (%) | 304 (52.50) | 177(60.20) | 127 (44.56) |
| Diabetes n (%) | 291 (50.25) | 168(57.14) | 123 (43.16) |
| Hypertension n (%) | 501 (86.52) | 241 (81.97) | 260(91.55) |
| Smoking n (%) | 2(0.35) | 1(0.34) | 1(0.35) |
| On statin n (%) | 324 (55.93) | 159 (54.08) | 165 (57.89) |
HDL – high density lipoprotein, LDL-low density lipoprotein, CV cardiovascular risk score
Table 1: Baseline Clinical Profiles of the Subjects
| Parameter | Female Prevalence | Male Prevalence |
| High Total Cholesterol (>5.2) | 44.1% | 28.8% |
| High LDL-C (>3.4) | 32.2% | 25.4% |
| Low HDL-C (<1> | 18.6% | 22.0% |
| High Triglycerides (>1.7) | 27.1% | 30.5% |
HDL – high density lipoprotein, LDL-low density lipoprotein
Table 2: Gender-based prevalence of Dyslipidemia
| Comorbidity Group | No Dyslipidemia | With Dyslipidemia | Total Participants | Prevalence (%) |
| None | 12 | 14 | 26 | 53.85% |
| Single | 195 | 159 | 354 | 44.92% |
| Multiple | 68 | 131 | 199 | 65.83% |
Table 3: Prevalence of dyslipidemia by comorbidity group
| Lipid Level | T-statistic | P-value |
| Total Cholesterol | -2.589 | 0.010 |
| LDL-C | -2.199 | 0.029 |
| HDL-C | 2.222 | 0.027 |
| Triglyceride (Tg) | -0.534 | 0.594 |
| CV Score % | -0.437 | 0.662 |
HDL – high density lipoprotein, LDL-low density lipoprotein, CV cardiovascular risk score
Table 4a: Comparison of lipid levels and CV risk between different groups (Hypertensive vs. Non-Hypertensive)
| Lipid Level | T-statistic | P-value |
| Total Cholesterol | 0.317 | 0.751 |
| LDL-C | 0.382 | 0.703 |
| HDL-C | -1.268 | 0.206 |
| Triglyceride (Tg) | 0.315 | 0.753 |
| CV Score % | 1.590 | 0.113 |
HDL – high density lipoprotein, LDL-low density lipoprotein, CV cardiovascular risk score
Table 4b: Comparison of lipid levels and CV risk between different groups (Diabetic Vs. Non –Diabetic)
| Lipid Level | T-statistic | P-value |
| Total Cholesterol | 6.951 | 0.000 |
| LDL-C | 6.963 | 0.000 |
| HDL-C | -2.889 | 0.004 |
| Triglyceride (Tg) | 1.713 | 0.087 |
| CV Score % | 5.081 | 0.000 |
HDL – high density lipoprotein, LDL-low density lipoprotein, CV cardiovascular risk score
Table 4c: Comparison of lipid levels and CV risk between different groups (Statin Users Vs Non Statin-Users)
| Variable | OR | 95% CI | P-Value |
| Age | 1.030 | (1.005, 1.055) | 0.018 |
| Gender | 1.075 | (0.379, 0.524) | 0.753 |
| Hypertension | 1.672 | (-0.060, 1.089) | 0.079 |
| Diabetes | 1.163 | (-0.338, 0.640) | 0.544 |
| Statin Use | 0.995 | (-0.467, 0.457) | 0.983 |
| Constant | 0.204 | (-2.730, -0.447) | 0.006 |
Table 5: Multivariable logistic regression-(assessing independent effects on dyslipidemia)
The higher prevalence of dyslipidemia observed in females in this age group reflects well-established patterns in cardiovascular risk factors, underscoring the importance of gender-specific strategies for managing dyslipidemia and cardiovascular risk in older adults. The findings of this study are consistent with numerous others, which show that older women tend to have higher levels of LDL cholesterol and total cholesterol, while men typically exhibit higher HDL cholesterol and lower triglyceride levels. These differences are likely attributed to hormonal, metabolic, and body composition factors that change with age, particularly after menopause. [32-33]
In postmenopausal women, the decline in estrogen levels can lead to an increase in LDL cholesterol and a decrease in HDL cholesterol. Estrogen is known to have a protective effect on lipid profiles, and its reduction after menopause may contribute to the rise in cholesterol levels observed in older women. [34-35] Multiple studies found that women over the age of 50 were more likely to have high cholesterol compared to men, whereas younger adults typically show higher cholesterol levels in males. This age-related increase in gender differences in lipid profiles aligns with broader trends in the literature, suggesting that aging and hormonal changes play a significant role in this variations.[32, 36]
Additionally, differences in body fat distribution between males and females may contribute to the higher triglyceride levels observed in women in this study. Women generally have more body fat, which can lead to higher triglyceride levels, as fat cells produce adipokines that influence lipid metabolism, promoting increased triglyceride production.[37-39] Furthermore, higher triglycerides and lower HDL cholesterol levels in women are associated with a greater prevalence of metabolic syndrome, a condition that increases the risk of cardiovascular disease. Some studies indicate that older women with metabolic syndrome tend to have significantly higher triglyceride levels than men, which may help explain the gender differences observed in this study.[37-38]
Hypertensive patients in our study exhibited significantly lower total cholesterol and LDL-C levels but higher HDL-C levels compared to non-hypertensive individuals. While some studies suggest that hypertension is commonly associated with dyslipidemia, characterized by elevated total cholesterol, LDL-C, and triglycerides, along with decreased HDL-C, other research, including findings similar to ours, particularly in treated hypertensive patients, shows mixed results.[40-43] It is possible that the hypertensive group in our study is well-managed with medications that influence lipid profiles, contributing to the observed differences.
In contrast, no significant differences in lipid levels or cardiovascular (CV) scores were found between diabetic and non-diabetic individuals in our study. Many studies have consistently shown that diabetes is linked to a higher risk of dyslipidemia, characterized by increased triglycerides, lower HDL-C, and a higher proportion of small dense LDL particles.[44-45] The absence of significant differences in our dataset could be due to several factors: the inclusion of well-managed diabetic patients with optimized lipid profiles through medication and lifestyle interventions, a sample size too small to detect significant differences, or other unaccounted factors influencing the results.[45-46]
Additionally, statin users in our study displayed significantly different lipid profiles and CV risk scores compared to non-users. Specifically, statin users had higher total cholesterol, LDL-C, and CV scores, but lower HDL-C levels. While this finding may seem counter-intuitive, it aligns with clinical practice. Statins are prescribed to individuals with higher cholesterol levels, so the observed higher cholesterol levels likely reflect pre-treatment conditions. Statin therapy is known to lower LDL-C and total cholesterol, while modestly increasing HDL-C and reducing triglycerides, explaining the lipid profile changes in this group.[47-48]
Lastly, individuals with both hypertension and diabetes showed a significantly higher risk of dyslipidemia compared to those with only one or neither condition. This supports existing literature on the synergistic effect of multiple metabolic disorders on lipid metabolism. Our findings highlight the importance of integrated screening and management strategies for older adults with multiple comorbidities, to reduce the cardiovascular risks associated with this conditions.[49-51]
This analysis provides important insights into the lipid profiles and cardiovascular risk factors in an elderly population with a high prevalence of comorbidities. It revealed that hypertension is significantly associated with altered lipid profiles among the study population. In contrast, diabetes mellitus did not demonstrate a statistically significant association with lipid levels within this dataset. Furthermore, statin therapy was linked to marked differences in both lipid profiles and cardiovascular risk scores, likely reflecting its prescription in individuals with elevated cholesterol levels. These findings have important clinical implications and may contribute to more targeted risk stratification and management strategies in elderly patients presenting with dyslipidemia and associated comorbidities.
Since this study relies on secondary data from the electronic health records (EHR) of Garki Hospital, the accuracy and completeness of the findings depend on the quality of the original records. Additionally, because the study used a cross-sectional design, it can only establish associations between comorbidities and dyslipidemia in older adults, rather than determining causal relationships. Consequently, the temporal dynamics between comorbidities and changes in lipid profiles cannot be assessed. Furthermore, the study sample is limited to patients who visit Garki Hospital, which may not fully represent the broader older adult population, especially those who do not seek medical care or those from different regions or socioeconomic backgrounds. This limits the generalizability of the findings to other areas of Nigeria. While the dataset includes information on medications like statins or antihypertensive drugs, variations in medication dosage, adherence, and potential drug interactions may not be fully captured, which could affect the lipid profiles observed in the study.
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Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
