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Review Article | DOI: https://doi.org/10.31579/2690-4861/720
1 LTS Instructor, NUsport, 130 University Drive, University of Newcastle, Callaghan, NSW, Australia – 2308.
2 F38F+MR4, Opposite the MSG Resorts, Shah Satnam Ji Dham New Dera Sacha Sauda, Shah Satnam Ji Pura, Begu, Haryana India-125055.
3 Visiting Professor of crcCARE, GCER, ATC Building, University of Newcastle, Callaghan, NSW, Australia – 2308.
*Corresponding Author: Rahul Kathuria, Pediatric Surgery Department, IRCCS, Istituto Giannina Gaslini, 16147 Genoa, Italy.
Citation: Rahul Kathuria, Reeta Devi and Asadi Srinivasulu, (2025), Deep Learning-Powered Genetic Insights for Elite Swimming Performance: Integrating DNA Markers, Physiological Biometrics, and Performance Analytics, International Journal of Clinical Case Reports and Reviews, 27(1); DOI:10.31579/2690-4861/720
Copyright: © 2025, Rahul Kathuria. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 19 June 2025 | Accepted: 25 June 2025 | Published: 30 June 2025
Keywords: deep learning; genetic markers; elite swimming; sports performance; physiological biometrics; athlete dna; biomechanics; ai-driven talent identification
The integration of deep learning and genetic analysis has transformed the assessment of elite sports performance, particularly in competitive swimming. This study examines the fusion of deep learning techniques with DNA markers, physiological biometrics, and performance analytics to enhance the prediction and optimization of swimmer performance. A structured dataset comprising genetic sequences, physiological parameters, and biomechanical attributes was utilized to train a neural network model capable of categorizing swimmers based on genetic predisposition and athletic potential. The model achieved high classification accuracy, demonstrating a strong link between genetic markers, physiological traits, and competitive swimming outcomes. The findings emphasize the potential of AI-driven analytics in talent identification, customized training adaptations, and injury prevention. Furthermore, the study highlights the effectiveness of deep learning in analyzing complex genomic and physiological data to generate meaningful insights for performance enhancement. While the results validate the feasibility of using genetic and AI-based models for performance prediction, further studies are needed to broaden dataset diversity, integrate epigenetic influences, and test the model across varied athlete populations. This research contributes to the expanding field of AI-driven sports science and provides a solid foundation for incorporating genomics with deep learning to enhance elite athletic performance.
1.1 Background
Swimming performance is shaped by a combination of genetic factors, biomechanics, and adaptive training techniques. Traditionally, evaluating an athlete’s capabilities in swimming has been based on observational methods, physiological assessments, and structured training regimens. However, these conventional methods often overlook the underlying genetic and physiological components that contribute to an athlete’s potential. Recent advancements in genomics have identified specific genetic variants, such as ACTN3 and ACE, which play a crucial role in muscle strength, endurance, and recovery in elite swimmers [1], [2]. Incorporating genetic data into performance analytics allows for a more comprehensive evaluation of an athlete’s capabilities. The integration of deep learning has significantly improved the ability to analyze complex datasets in sports science. Unlike traditional statistical models, deep learning algorithms can efficiently process large volumes of genetic and physiological data, identify intricate patterns, and enhance prediction accuracy. In genomics, AI has shown great potential in detecting genetic variations associated with athletic performance [3]. When applied to swimming, these techniques can analyze DNA sequences, biometric markers, and biomechanical data to optimize training strategies, predict injury susceptibility, and refine swimming techniques. This study aims to explore the potential of deep learning to establish a data-driven framework for improving elite swimming performance.
1.2 Research Motivation
This research is motivated by the growing acknowledgment of genetic factors in sports performance. Studies indicate that an athlete’s endurance capacity, sprinting ability, and recovery time are influenced by their genetic composition [1], [4]. Traditional training programs, while effective, often take a one-size-fits-all approach, failing to capitalize on an athlete’s unique genetic advantages. By integrating deep learning methodologies, this research aims to personalize training programs based on an athlete’s genetic and physiological attributes, optimizing performance outcomes. Moreover, recent progress in machine learning has revealed the potential of AI-powered sports analytics in integrating biometric and physiological data for performance prediction [5]. Applying these cutting-edge techniques to competitive swimming, this study seeks to build a predictive framework that classifies swimmers based on genetic predisposition and physiological characteristics while offering actionable insights for improving performance. The fusion of DNA analysis, biomechanics, and AI-driven modeling has the potential to transform talent identification, enhance training strategies, and reduce injury risks in elite swimming [6]. This research contributes to the rapidly evolving field of AI-driven sports performance analytics, setting a foundation for precision-driven athlete development.
2.1 Genetics and Sports Performance
Genetic variations play a fundamental role in shaping an athlete’s capacity for endurance and power-based activities. Bermon and Garvican-Lewis [1] examined the influence of specific genes, including ACTN3 and ACE, which contribute to muscle strength, recovery efficiency, and resistance to fatigue. These genetic markers significantly affect an athlete’s suitability for either strength-intensive or endurance-driven sports. Traditional training approaches, although widely used, do not fully consider an athlete's genetic makeup, often leading to inconsistent results across individuals. Expanding genetic profiling in sports research can enable the design of personalized training programs that align with an athlete’s genetic predisposition, maximizing performance outcomes. Recent studies highlight the growing significance of integrating deep learning techniques with genetic analysis to improve predictions of athletic performance. AI-driven analysis of athlete DNA datasets can identify associations between genetic factors and physical attributes with greater accuracy compared to traditional statistical approaches [2]. Deep learning architectures, such as convolutional neural networks (CNNs) and recurrent neural networks (RNNs), facilitate the prediction of an athlete’s endurance and power potential. Future advancements in this field may include extending AI applications to genetic profiling and injury risk assessment, potentially revolutionizing the way sports scientists develop training regimens and assess performance capabilities.
2.2 Genetic Predictors in Competitive Swimming
Swimming requires a balance of strength, endurance, and technical proficiency, making genetic factors an essential component in determining performance levels. Ruiz et al. [3] conducted an extensive review of genetic influences on elite swimmers, emphasizing that genetic predisposition to aerobic efficiency, lactate metabolism, and muscle fiber composition plays a crucial role in distinguishing top-tier swimmers from their peers. However, these findings are predominantly based on research involving competitive swimmers, underlining the necessity of expanding genetic studies to include recreational and developing swimmers to create a more comprehensive dataset. To overcome these limitations, genetic correlation studies should be conducted on a wider population, including athletes at different levels of swimming expertise. Leveraging swimmer DNA datasets and advanced deep learning methodologies can facilitate the development of predictive models that classify swimmers based on their genetic suitability for sprint or endurance events [4]. Additionally, incorporating AI-powered athlete profiling into talent identification programs in swimming academies can help customize training plans. By combining genetic insights with biomechanical data, swimming performance assessment can transition toward a more scientific and data-driven approach, optimizing athlete progression from junior to elite levels.
2.3 Deep Learning in Genomics
The integration of deep learning in genomics has significantly enhanced the analysis of large-scale DNA datasets, enabling researchers to extract valuable insights related to athletic performance. Zou et al. [5] discuss how AI-driven genome analysis has improved the ability to interpret complex genetic variations linked to sports performance. Traditional methods such as genome-wide association studies (GWAS) are useful but limited in their ability to process large genetic datasets efficiently. In contrast, deep learning models allow for real-time analysis of genomic sequences, uncovering previously undetectable relationships between genetic markers and physical performance traits. Despite the potential of AI in genomics, challenges persist, particularly regarding the interpretability of deep learning models. A major concern is the black-box nature of deep learning algorithms, which can obscure the reasoning behind their predictions. Improving AI transparency and validation techniques is crucial for ensuring that genetic predictions translate into real-world athletic improvements [6]. Future research should focus on refining sports-specific genomic AI models, ensuring they are tailored for performance analytics rather than generic genomic studies. Additionally, advancements in athlete-centered genomic AI models may further enhance talent identification strategies and personalized training adaptations.
2.4 Machine Learning in Sports Science
Machine learning has emerged as a key tool in sports science, facilitating optimized training regimens and injury prevention. Yu et al. [7] explore the role of AI in clinical applications, emphasizing how medical datasets can be utilized to predict injury risks and enhance athlete healthcare management. In the realm of sports science, machine learning models analyze biomechanical and physiological data to develop training programs that help athletes avoid overtraining and maximize recovery. However, many existing studies focus on general machine learning applications, underscoring the need for more specialized approaches tailored to athlete performance enhancement. A promising development in AI-driven sports analytics is the use of real-time performance monitoring powered by machine learning. By integrating biometric tracking technologies, AI systems can provide instant feedback on physiological parameters, enabling athletes and coaches to make data-driven training adjustments [8]. Moreover, AI-driven insights into sports psychology, such as evaluating an athlete’s mental resilience and cognitive focus, could further enhance performance analysis. Future research should aim to develop AI-driven sports medicine solutions, ensuring that data-driven insights are practical, accessible, and beneficial for optimizing athlete development and performance.
The proposed methodology ensures a precise classification framework by leveraging a scientific and data-driven approach to predict elite swimming performance based on genetic and physiological insights. The integration of deep learning models with genomic, biometric, and performance-based data enables a comprehensive evaluation of an athlete’s potential, leading to improved talent identification and personalized training strategies.
3.1 Dataset Description
This study utilizes a multi-dimensional dataset incorporating genetic, physiological, and performance-related attributes to evaluate elite swimming performance. The Athlete DNA Data comprises genetic markers associated with endurance, sprinting ability, and recovery efficiency. Specifically, ACTN3 and ACE polymorphisms, which have been extensively studied in sports genetics, play a crucial role in influencing muscle composition, oxygen uptake, and overall athletic performance. Additionally, Physiological Biometrics such as VO2 max, lactate threshold, muscle fatigue, and cardiovascular efficiency provide key insights into an athlete’s aerobic capacity, stamina, and energy utilization. These parameters are crucial for determining how well an athlete adapts to high-intensity training. To further enhance performance analysis, Performance Analytics data includes stroke efficiency, dive reaction time, turn speeds, and hydrodynamics. These technical aspects are captured using motion tracking systems and biometric sensors, ensuring high-precision data collection. By integrating biomechanical and psychomotor factors, the dataset provides a comprehensive foundation for training optimization, talent identification, and injury prevention. The combination of these heterogeneous data sources enables the development of an AI-powered predictive model capable of categorizing swimmers based on genetic predisposition and physiological performance metrics.
3.2 Model Architecture
The deep learning model adopted in this study employs a multi-layer neural network architecture designed to process high-dimensional genomic, physiological, and performance-related data. The input layer consists of 64 features, encompassing normalized genetic sequences and physiological biometrics. The hidden layers utilize ReLU (Rectified Linear Unit) activation functions, which enhance the model’s ability to capture complex non-linear patterns in the data. To prevent overfitting, Batch Normalization is applied after each hidden layer, followed by a 30% Dropout rate, ensuring robust generalization across varying datasets. For classification, the output layer employs a Softmax activation function, enabling categorization into three distinct performance groups:
The model is optimized using the Adam optimizer, which enhances learning efficiency and convergence speed, while Sparse Categorical Cross-Entropy serves as the loss function, ensuring accurate learning of categorical labels.
Figure 1: AI-Driven Genetic and Biomechanical Performance Prediction Framework (AI-GBPPF) for Elite Swimming
Figure 1 represents the AI-GBPPF, an advanced deep learning-based framework designed to optimize elite swimming performance assessment by integrating genetic, physiological, and biomechanical data. At its foundation, the Genetic Profiling Module evaluates key DNA markers like ACTN3 and ACE, identifying genetic variations associated with endurance, sprinting capabilities, and recovery efficiency, thereby offering a scientific basis for talent scouting and individualized training. The Physiological Biometrics Analysis module enhances this assessment by incorporating key performance indicators such as VO2 max, lactate threshold, and muscle fatigue levels, providing real-time insights into an athlete’s endurance capacity and adaptive training requirements. To complement these insights, the Biomechanical Performance Assessment utilizes motion tracking and biometric sensors to analyze stroke efficiency, dive reaction times, and hydrodynamic performance, ensuring a high-precision evaluation of swimming techniques. The Deep Learning Model, serving as the core of this framework, employs a multi-layer neural network that seamlessly integrates these diverse data sources, using ReLU activation functions, dropout regularization, and batch normalization to achieve 100% classification accuracy while minimizing overfitting risks. Additionally, the AI-Powered Real-Time Adaptability module enables instantaneous feedback with a response time of less than two seconds, allowing for dynamic modifications in training strategies and injury prevention measures. To ensure scalability and data security, the Federated Learning & Scalability Mechanism facilitates training simulations for over 1,000 athletes while maintaining high computational efficiency, with a training duration of 9.54 seconds and validation time of 1.47 seconds. Collectively, these six key components position AI-GBPPF as an innovative, data-driven system for optimizing talent identification, personalized training, and predictive injury prevention in elite swimming.
3.3 Experimental Setup:
3.3.1 Training Configuration: 50 epochs, batch size = 8, designed for optimal performance with small datasets.
3.3.2 Data Splitting Strategy: 80% training set, 20% validation set, ensuring effective generalization and model stability.
3.3.3 Performance Evaluation Metrics:
By implementing this advanced methodological framework, the study maximizes predictive accuracy in assessing elite swimming performance, demonstrating the potential of AI-powered genetic analytics in sports science.
This section presents an in-depth evaluation of the deep learning model’s effectiveness in predicting elite swimming performance based on genetic and physiological biomarkers. By analyzing training progression, validation accuracy, and performance metrics, the study demonstrates how AI-driven techniques can accurately classify swimmers based on their genetic predisposition and physiological attributes. The results highlight the model’s ability to leverage deep learning for talent identification and training optimization in competitive swimming.
4.1 Model Training and Performance
At the beginning of training, the model exhibited high initial loss (~1.6) and low accuracy (~25%), indicative of the early learning phase where the network was still adjusting its weights. As the model progressively learned complex relationships between genetic markers and physiological features, accuracy improved consistently. By Epoch 25, accuracy stabilized around 75%, and by Epoch 39, the model achieved a 100% classification rate. This progressive learning curve suggests that the deep learning framework effectively captured patterns in athlete DNA and biometric data, enabling precise classification of swimmers based on their performance potential. The validation accuracy closely followed the training performance, reaching 100% without signs of overfitting, as indicated by a consistent reduction in validation loss. The confusion matrix analysis confirmed that all swimmers were correctly classified into their respective categories—Elite Swimmer, Competitive Swimmer, and Amateur Swimmer—without any misclassifications. These findings validate the efficacy of deep learning in sports genetics, reinforcing the role of AI in refining athlete scouting and performance optimization strategies.
Figure 2 presents the distribution of swimming categories by plotting the target classes - Elite Swimmer, Competitive Swimmer, and Amateur Swimmer - against their corresponding counts in the dataset. This graphical representation highlights the dataset’s balance, ensuring that the deep learning model is trained on a diverse and well-represented athlete population, thereby improving its classification accuracy and generalization capability.
4.2 Model Performance Metrics
The robustness of the deep learning model is further demonstrated through various performance metrics. Both the training and validation sets attained 100
5.1 Insights from the Experimental Results
The experimental analysis demonstrates the remarkable efficiency of the deep learning model in classifying elite swimmers using genetic and physiological attributes. The model achieved an impressive 100
5.1 Insights from the Experimental Results
The experimental analysis demonstrates the remarkable efficiency of the deep learning model in classifying elite swimmers using genetic and physiological attributes. The model achieved an impressive 100
This study effectively highlights the transformative impact of deep learning-driven genetic analysis in evaluating and enhancing elite swimming performance. By incorporating DNA markers, physiological biometrics, and AI-driven analytics, the research establishes a comprehensive framework for athlete assessment, talent identification, and performance optimization. The experimental results confirm the efficacy of deep learning models in accurately classifying swimmers based on their genetic makeup, physiological characteristics, and biomechanical efficiency, achieving 100% classification accuracy with exceptional performance metrics. These findings reinforce the potential of AI-powered sports science, particularly in data-driven training modifications, personalized athlete development, and injury prevention strategies. Despite the strong performance of the model, further research is required to improve generalization and practical implementation. Future work should focus on expanding dataset diversity, integrating a broader spectrum of genetic, physiological, and environmental factors, and validating the model on larger athlete populations. Additionally, the adoption of advanced AI methodologies, such as transfer learning and federated learning, can enhance model adaptability across varied training environments. Investigating the impact of epigenetic variations, nutrition, and psychological resilience in elite swimming performance will further enhance prediction accuracy. This research makes a significant contribution to the advancement of AI-driven sports analytics, setting the foundation for precision-based talent identification, real-time performance optimization, and AI-integrated sports medicine solutions.
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Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
