AUCTORES
Globalize your Research
Review Article | DOI: https://doi.org/10.31579/2690-4861/086
*Corresponding Author: Habip Gedik, Department of Infectious Diseases and Clinical Microbiology, Ministry of Health Bakırköy Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Citation: H Gedik. (2020) Clinical complications and challenges during the follow-up of inpatients with COVID-19. International Journal of Clinical Case Reports and Reviews. 4(5);DOI: 10.31579/2690-4861/086
Copyright: © 2020 Habip Gedik, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 27 October 2020 | Accepted: 28 November 2020 | Published: 07 December 2020
Keywords: COVID-19; diagnosis; follow-up; complications
Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), affecting people. Turkey was reported to the public by COVID-19 first cases of the Ministry of Health on March 10, 2020; and 520,167 cases and 14316 deaths were reported on December 03, 2020, respectively. The survival of these patients is usually determined over a 7-day intensive care follow-up. The survivors begin to recover clinically after the 15th day. So the riskiest period in terms of mortality is between 7-14 days. The antiviral called Favipiravir was administered only to intensive care patients in the first period and then allowed to patients in the clinic with oxygen saturation below 90% to achieve an improvement in the early period of patients with impaired oxygen saturation. But, it did not benefit patients with support with mechanical ventilation in ICU and their mortality rates. The cause of death is generally a respiratory failure due to the functional loss of lungs. Antiviral treatment is certainly needed to administer in the early period of disease to prevent a severe inflammatory response.
COVID-19 (COVID-19), long coronavirus disease 2019; an infectious respiratory disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), affecting people [1]. The disease, first discovered in Wuhan, China's Hubei province in 2019, has spread worldwide. Since its discovery caused a 2019-20 coronavirus pandemic. As of 9 May 2020, more than 3 759 967 cases have been reported across 187 countries and territories, resulting in more than 259 474 deaths. More than 1.31 million people have recovered. [1, 2] Turkey was reported to the public by COVID-19.The Ministry of Health reported the first case with covid-19 on March 10, 2020, and 520,167 cases and 14316 deaths were reported on December 03, 2020 respectively. [3]
Super silent spreaders are active in the vial transmission. Because, super silent spreaders, whose immune response is insufficient or unreturned, allow the virus to reproduce silently and that is a major factor in the spread of the disease. [4, 5] According to our observation, the virus binds to the upper respiratory epithelium and reproduces itself. [6, 7] After that it makes its first viremia, infecting almost all organs such as lung, brain, intestine, muscles, vascular structure, after viremia, and revealing related clinical pictures. [8-11] In other words, we do not think that the virus reaches the lung and creates an infection. If this were the case, there would not be so many patients, due to the spread of the virus and the number of infected people. Since the amount of virus that would reach the lung was prevented by physiological barriers.
Clinical and radiological findings were more helpful in diagnosing patients, since the result of the PCR test was concluded 1-2 days after application. Although the PCR test was negative, we found that patients with clinical and thoracic tomography findings were predominant. CT is more sensitive in diagnosis than the PCR test (Another issue is the situation of people who have no clinical findings, but who have PCR positivity. First, the false positivity of the PCR test, unfortunately, did not allow questioning due to the severity of the pandemic during this period. It will be useful to evaluate samples, such as oropharynx, nasopharynx, sputum, etc. and to support the results with antigen screening tests to reveal false positivity of these individuals. [12, 13] We suppose that these people have the real PCR positivity, so is this action in the transmission? As we have the case of Tuberculosis disease, sputum PCR samples remain positive for some time in patients receiving tuberculosis treatment, although sputum culture and smear tests are negative. We know that the PCR positivity here is not infectious. In this case, can the PCR Covid-19 viral load value be taken into account? Because, how effective is it in transmitting low PCR positivity? Is it infectious?
The Republic of Turkey, Ministry of Health has published a COVID-19 treatment guideline to avoid treatment chaos in the management of patients with COVID-19. [14] According to the guideline, hydroxychloroquine + azithromycin + oseltamivir (due to the Influenza season) was initiated to patients with clinical and/or radiological findings and hospitalized in the first months of pandemi until the PCR test results were obtained. [14] Hydroxychloroquine did not prevent the development of infection, as COVID-19 developed in patients who receive that drug for the treatment of Systemics lower case lupus erythematosus. Moreover, that drug did not reduce the intubation need of patients whose oxygen saturation was impaired or subsequently deteriorated. These patients were over the age of 50 and had at least one chronic disease. [15, 16] Only one patient who was receiving azithromycin and hydroxychloroquine therapies developed a QT-prolonged arrhythmia. And another patient developed acute renal failure. Other patients tolerated these two drugs comfortably.
Favipiravir, which was later brought from China by the Ministry of Health and was administered only to intensive care patients in the first period, and then patients with oxygen saturation below 90% in the clinics to benefit in the early period. But it did not benefit patients followed up in ICU and reduce the mortality rates in patients supported with mechanical ventilation. [17] It is suggested that the impaired immune system and physiological barriers of patients due to chronic diseases and risk factors could not provide an adequate response against the virus facilitating the development of sepsis and causing the body defeated in the struggle against COVID-19 when the burden on the body caused by sepsis is added to the weak body. [18] Favipiravir is administered for a total of five days, but the clinical deterioration period develops in the next period. In spite of favipiravir the clinical deterioration does not end, as the inflammatory response or attack continues. It turns out that even if the proliferation of the virus is prevented by favipiravir. The virus related structures trigger the inflammatory response strongly and constantly.
There is a need for an antiviral treatment that could be administered in the early period and prevent a severe inflammatory response. Secondly, the virus causes different clinical presentations in patients with COVID-19. The severity of the disease may be related to not only viral load but also subtypes of the virus, as with Influenza viruses. Therefore, those subtypes cause a different virulence and immune response. The subdivision of the global SARS-CoV-2 population was defined well in sixteen subtypes by focusing on the widely shared polymorphisms in nonstructural cistrons (nsp3, nsp4, nsp6, nsp12, nsp13, and nsp14), structural (spike and nucleocapsid) and accessory (ORF8) genes. Six virus subtypes were reported to be predominant in the population, but all sixteen showed amino acid replacements which could have phenotypic implications. [19]
A significant portion of inpatients was male with rates of 60% at our hospital. The course of infection caused by COVID-19 was not serious in patients who were between 18 and 50 years old and had no underlying disease. The prominent features of the patients followed up in ICU is the age over 50 years old (80% of them), being male and possession of at least one underlying disease (such as chronic obstructive pulmonary disease (COPD), diabetes mellitus, heart failure, chronic kidney failure, obesity, Alzheimer's disease, etc.). The survival of these patients is usually determined over a 7-day intensive care follow-up, and the survivors begin to recover clinically after the 15th day. So the riskiest period in terms of mortality is between 7-14 days. The cause of death is generally a respiratory failure due to lung function loss. In the intensive care unit (ICU), almost all patients are older than 50 years old and have one or more risk factors. Therefore, almost all of the patients who do not have risk factors under the age of 50 recovers, even if the clinical presentation is severe. [20]
There was no relationship between increased D-Dimer values and a need for mechanical ventilation, high values of D- Dimer up to 80000 µg / L returned to normal during the follow-up. Before anticoagulant use was recommended by the Ministry of Health treatment guideline, patients with very high D-Dimer values did not develop a pulmonary embolism during the hospital follow-up period Two patients, who were younger than 50 years old, were admitted to the hospital with pulmonary embolism and COVID-19 infection. In one patient, a pulmonary embolism developed 5 days after discharge. Anticoagulant therapy was routinely performed on inpatients who were over 50 years of age and those with underlying disease, and pulmonary embolism was not detected. The diagnosis of pulmonary embolism was performed as a result of CT-Angiography and these patients were discharged with anticoagulant treatment without any complications. It was observed that increased D-Dimer value is a component of vasculitis caused by COVID-19. Those values returned to normal range with the recovery of the disease during the period when anticoagulant use was not routinely. However, it will be beneficial to start anticoagulants in terms of complications that may develop if this vasculitis table is more than 50 years old, with underlying disease, and with D- Dimer value above 2000 µg/ L. [21]
Neurological symptoms (such as agitation, personality changes, lower limb paresthesia, ataxic movements) are also observed due to the formation of meningoencephalitis and meningomyelitis together with the vasculitis table of this virus. [22, 23] The reporting of Guillain-Barre syndrome cases related to Covid-19 supports this. [24] The long duration of these neurological findings supports the fact that the PCR result of patients is negative during the periods when the PCR result is negative. Symptomatic treatment for neurological findings shows benefits in patients.
CRP values are generally above 50 mg/dl at first admission in patients with Covid-19 regardless of bacterial infections. Therefore, it would be appropriate to consider leukocytosis and elevated procalcitonin value more in terms of bacterial infection. If there is a history of COPD and asthma in patients with extensive lobar or lobular infiltration on thorax CT, care should be taken in terms of secondary bacterial pneumonia, and antibiotics should be initiated. Although azithromycin is in the Covid-19 treatment guideline of our country, a beta-lactam antibiotic (ceftriaxone or cefotaxime) should be started by evaluating the clinical findings in patients with leukocytosis due to macrolide resistance in pneumococci.
It has been observed that third-generation cephalosporins are sufficient for the treatment of bacterial pneumonia, which develops secondary to the development of complications due to extending the length of hospitalization in intubated patients. However, in patients with increased leukocytosis and higher procalcitonin values, tazobactam-piperacillin and carbapenem may be included in the selection of broader spectrum antibiotics for the treatment of complications during the prolonged intubation time. Also, in intensive care patients, fever is seen as a part of Covid-19 infection, and it is not necessary to start a broad-spectrum antibiotic. Fever rarely extended to 10-14 days after the 7th day and then spontaneously decreased. For this reason, in patients followed up with Covid-19 in intensive care, a fever could be encountered as a part of viral disease rather than a bacterial infection. Blood cultures of patients with fever yielded no bacteria in patients with fever, until the length of stay at the intensive care unit as being intubated prolonged and secondary infection as a complication of prolonged intubation.
Although there are high expectations regarding vaccination, the following two issues will probably come up: First, whether the immunization rate in Coronavirus vaccine will be at the expected level or not, even the efficacy rates of the Influenza vaccine did not exceed 40-60%. [25] It is also a known fact that antibody response to inanimate vaccines is weak in older people. Therefore, if a certain level of at least 60-70% of the population is obtained with a vaccine to be produced, at least the spread of the virus will decrease, but the risk will continue for those with advanced age and underlying disease. Therefore, the availability of a drug is more important in this age group because the disease is more mortal. Again, mutations are reported in Covid-19 with such high replication and spread rates. Therefore, it is known that the vaccine will not have any effect after some time with the accumulation of these mutations.
Finally, everybody asks ''When will this pandemic end? ''. I think this question could be answered in two sentences: First, let's not forget that the first SARS outbreak that occurred in 2003 ended in 2005, about a year and a half. Secondly, even though it is reported that the number of cases in a country has decreased or not, it should be noted that in a world where borders are almost removed by travel, this epidemic may have ended all over the world.
Acknowledgment:
This article includes my personal observations that I have performed during my duty in Taksim Training and Research Hospital with 200 clinic beds and 38 intensive care beds, were covid-19 patients were followed, and published studies.
Conflict of Interest
There is no conflict of interest.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
