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Case Report | DOI: https://doi.org/10.31579/2578-8965/285
1Obgyn resident at Dubai Health, United Arab Emirates (UAE).
2Consultant Obgyn at Dubai Health, United Arab Emirates (UAE).
*Corresponding Author: Asma Mohammed, Obgyn resident at Dubai Health, United Arab Emirates (UAE).
Citation: Malaz Hamid, Asma Mohammed, Ethar Mahmoud Nazal, Atif Fazari, (2025), A Brief Overview of Our Case Report and other Previous Studies About Pseudomyxoma Peritonei in Pregnant Case, J. Obstetrics Gynecology and Reproductive Sciences, 9(7) DOI:10.31579/2578-8965/285
Copyright: © 2025, Asma Mohammed. This is an open-access article distributed under the terms of The Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 22 September 2025 | Accepted: 29 September 2025 | Published: 07 October 2025
Keywords: large pelviabdominal mass; pseudomyxoma peritonei; pregnancy; dpam, pmca
Pseudomyxoma peritonei (PMP) is a rare clinical condition characterized by mucinous ascites and peritoneal implants, typically originating from the appendix or ovary. Its occurrence during pregnancy is exceedingly rare and presents significant diagnostic and therapeutic challenges. We present the case of a 36-year-old primigravida at 19 weeks gestation, presenting with progressive abdominal distension and jaundice. Imaging revealed a large pelviabdominal mass, initially suspected to be a degenerating fibroid. Exploratory laparotomy revealed a massive mucinous tumor. Histopathology confirmed pseudomyxoma peritonei. The patient underwent surgical management with a successful outcome. This case highlights the diagnostic dilemmas and surgical considerations in managing PMP during pregnancy.
In conclusion, pseudomyxoma peritonei in pregnancy is a diagnostic and management challenge. High clinical suspicion, careful imaging, and timely surgical intervention are crucial. This case adds to the limited body of literature and highlights the importance of considering rare diagnoses in atypical presentations.
Pseudomyxoma peritonei (PMP) often called ‘‘jelly belly’, is a rare cancer that generally presents as multifocal mucinous tumors in the abdominal cavity causing increased abdominal girth, pain and pressure on internal organs due to the accumulation of large amounts of mucinous tumor (Patrick-Brown et al., 2020; Garg et al., 2024). Pseudomyxoma peritonei (PMP) is a form of peritoneal malignancy. It originates from a perforated appendiceal epithelial tumor and affects 22 individuals per million worldwide (Patrick-Brown et al., 2020). The cancer spreads along the peritoneum, a thin layer that protects the abdominal organs, and can involve the surface of all abdominal organs. Without treatment, PMP is a fatal condition (Ionescu et al., 2024). The unlimited multiplication of peritoneum cells can fill the space needed in the abdomen for normal gastrointestinal functioning, leading to compression of bowel organs, disruption of their functioning, and starvation (Taher et al., 2024).
Initial presentation varies and consists of unspecified signs and symptoms that relate to the progression of the disease (García et al., 2019). These include increased abdominal girth, an appendicitis-like syndrome, a new-onset hernia, presence of a pelvic mass, or non-specific abdominal or pelvic pain (Awad et al., 2024). Progressive accumulation of mucinous material gradually fills and can compress vital organs within the peritoneal cavity, which can result in abdominal distention, ascites, bowel obstruction, and nutritional compromise (Arslan, 2023).
The prognosis with the histological features. These included disseminated peritoneal adenomucinosis (DPAM) and peritoneal mucinous carcinomatosis (PMCA), (Viloria and Amosco, 2023). DPAM consisted of peritoneal lesions composed of abundant extracellular mucin containing scant simple to focally proliferative mucinous epithelium with little cytologic atypia or mitotic activity, with or without an associated appendiceal mucinous adenoma (Ye and Zheng, 2022; Arrington, 2022). PMCA was composed of peritoneal lesions containing more abundant mucinous epithelium with the architectural and cytologic features of carcinoma, with or without an associated primary mucinous adenocarcinoma (Martín-Román et al., 2021).
The most common treatment for PMP is cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) (Papantoni et al., 2021). CRS entails removing the peritoneum and other affected tissues. CRS is an extensive and complex surgery. HIPEC is a therapy that uses chemotherapy that is applied directly to the abdomen (Karimi et al., 2024). Patients with PMP experience various stressful and traumatic events, including diagnosis with a rare disease, treatment with extensive and complex surgery, admission to intensive care for an average of 5 days, and then on a surgical ward for an average of 3 weeks (Taher et al., 2024).
For patients that cannot be cured by surgery, no effective treatments exist, and since PMP is a slow-growing cancer, patients may live for many years with active disease and worsening symptoms, presenting a substantial burden on the health-care system (Patrick-Brown et al., 2020). Estimation of prevalence is therefore essential for resource allocation. Prevalence estimates depend on the incidence rate, which for PMP have been widely quoted as approximately 1–2 people per million (Li et al., 2024).
A 36-year-old primigravida at 19 weeks gestation presented with acute abdominal distension, progressive discomfort, and jaundice. She had no previous surgical or medical history but was a known case of uterine fibroids. Physical examination revealed a markedly distended abdomen with a palpable pelviabdominal mass. Ultrasound and Magnetic Resonance Imaging (MRI) showed a large heterogeneous lesion measuring approximately 22×16×11 cm, suspected to be a degenerating fibroid, see figure 1a, b. Given the worsening symptoms, an exploratory laparotomy was performed, revealing a massive mucinous mass. The uterus was gravid and displaced by the lesion. Resection of the tumor was achieved, and samples were sent for histopathology, which confirmed pseudomyxoma peritonei.
Post operative course pregnancy follows up and delivery with outcome details
In our case there were no significant events observed in the postoperative course or pregnancy follow-up. Also, the patient was doing well and had no complaints; at the same time, the patient had received adequate analgesia, and she had passed urine and stool. Additionally, our case had tolerated an oral diet and mobilized adequately without assistance. Regarding the baby, it was admitted to the neonatal intensive care unit (NICU).
Figure 1a: Gross specimen of the resected mass showing a large, encapsulated lesion with a smooth, glistening surface and focal areas of vascularity and hemorrhage. The mass measures approximately 25 cm in greatest diameter.
Pseudomyxoma peritonei during pregnancy is extremely rare, and diagnosis can be delayed due to overlapping symptoms with pregnancy-related changes (Haase et al. 2009, Koyama et al. 2011). Imaging studies are limited due to fetal safety concerns, and definitive diagnosis often occurs intraoperatively (Sugarbaker, 2007).
Figure 1b: Another view of the same specimen is taken under different lighting to highlight its lobulated external surface. The scale below the mass shows the large size and irregular contour.
In our case, the mass was initially misinterpreted as a fibroid. Surgical exploration and resection during the second trimester proved safe and effective (Esquivel and Sugarbaker, 2000). Histological evaluation remains the gold standard for diagnosis (Ronnett et al., 1995). multidisciplinary planning, including gynecologists, surgeons, and pathologists, is essential for optimal outcomes (Bevan et al., 2010). In another case report in Egypt, by Mousa et al., (2021), A 27-year-old primigravida, at 30 weeks of gestation, was transferred to our tertiary care obstetric center. Her Gynecologists performed an US guided ovarian cyst aspiration five days ago with no improvement. Three-dimensional (3D) US showed a huge multilocular left ovarian cyst (20 cm) with smooth outline and contents showing heterogeneous echogenicity. No solid components or papillary projections were detected in the cyst. It also showed pelvi-abdominal ascites reaching the level of hepatorenal pouch. The patient had smooth postoperative recovery and was discharged on day 5 postoperative after her lab results approached normal values. She was counselled about comprehensive surgical staging with fertility preservation versus complete staging laparotomy (Maltaris et al., 2006, Marpeau et al. 2008).
Specimens were sent for tissue histopathology and fluid cytology examination. No intra-abdominal organs or peritoneal masses that might require cytoreduction were detected intraoperatively (Desai et al., 2014). However, in our case, Gross specimen of the resected mass showing a large, encapsulated lesion with a smooth, glistening surface and focal areas of vascularity and hemorrhage. Ultrasound and Magnetic Resonance Imaging (MRI) showed a large heterogeneous lesion measuring approximately 22×16×11 cm, suspected to be a degenerating fibroid. Indeed, 1% to 2% of pregnant women have an adnexal mass discovered on ultrasonography [9]. A review of the literature found only seven other cases of pseudo myxoma peritonei diagnosed during pregnancy (Table 1).
| Case | Our case | Ben Abdu2009 | Erika Haase 2009 | Shinsuke Koyama 2010 | Z. Manan 2010 | Sofia Jayi 2012 | Mousa et al. 2021 | Basso et al. 2022 |
| Age/yr | 36 years | 36 years old | 30 years old | 34 years old | 41 years old | 35 years old | 27-years-old | 34 years old |
| Diagnosis | Sepsis and disseminated Intravascular coagulopathy | Well-differentiated appendix mucinous adenocarcinoma with pseudomyxoma peritonei |
Well-differentiated appendix mucinous adenocarcinoma with pseudomyxoma peritonei | Transverse colon mucinous adeno Carcinoma with ovarian metastasis and pseudomyxoma peritonei | Well-differentiated appendix mucinous adenocarcinoma with pseudomyxoma peritonei | Mature teratoma and mucinous borderline ovarian tumor with pseudomyxoma peritonei | Sepsis and disseminated Intravascular coagulopathy | Well-differentiated appendix mucinous adenocarcinoma, with pseudomyxoma peritonei |
| Clinical presentation | Acute abdominal distension, progressive discomfort, jaundice | During cesarean section | Accidental finding in routine pre Natal ultrasound | Accidental finding in routine pre Natal ultrasound | During cesarean section | Abdominal pain | Acute Abdominal distension, discomfort and constipation | Abdominal pain |
| GA at presentation | 19 weeks | At delivery | 17 weeks | 24 weeks | At delivery | 22 weeks | 30 weeks | 29 weeks |
Management during pregnancy | Surgical exploration and resection during the second trimester proved safe and effective | Laparotomy with right salpingooophorectomy, appendectomy, Omental biopsy | Pararectus incision, Appendicectomy | Salpingooophorectomy, hysterectomy, omentectomy, appendicectomy, iliac lymphadenectomy | Huge multilocular left ovarian cyst (20 cm) | Laparotomy with right adnexa Tomy, omentectomy, Appendicectomy | ||
| Management delivery | Cesarean section at 36 weeks | Cesarean section for failure to induce labor 40 GW | Labor induction Vaginal delivery at 35 weeks | Cesarean section at 34 weeks | Labor induction for Macrosomia Cesarean section for failure to induce labor 40 GW | Pregnancy interruption at 22 WG | classical caesarean section (CS) | Labor induction Vaginal delivery at 37 weeks |
| Treatment | Complete cytoreductive surgery with HIPEC | Appendicectomy, right colectomy with HYPEC during cesarean | Complete cytoreductive surgery with HIPEC and systemic chemotherapy (8 cycles with Xeloda and oxaliplatin) | Complete cytoreductive surgery with bilateral salpingooophorectomy, partial resection of the transverse colons follow by chemotherapy (FOLFOX and bevacizumab) | Appendicectomy, mucus resection | Trial of conservative management with parenteral antibiotics, intravenous (IV) fluids, hemodynamic and respiratory support | Complete cytoreductive surgery with HIPEC | |
| Follow-up | Recurrence, 1 month after surgery | 5 years no recurrence | 6 months progressing | Lost of follow up | Recurrence, 4 weeks postoperative | Recurrence, 14 months after surgery |
Table 1: Cases of pseudomyxoma peritonei during pregnancy.
For this review, we included all studies on pseudomyxoma peritonei in pregnant women. We performed the search among articles in the PubMed database. The mesh terms used were “pseudomyxoma peritonei” and “pregnant women” or “pregnancy.” The search was extended to include the last 20 years. All types of studies were included. Titles and abstracts were read, and if the articles were relevant to the subject, they were selected. Pseudomyxoma peritonei syndrome is a peritoneal gelatinous disease associated in most cases with appendiceal adenocarcinoma intraperitoneal rupture. The discovery of an ovarian mass in pregnancy is often incidental during an obstetrical ultrasound (US) scan, as in the cases of E. Haase (2009) and S. Koyama (2011).
Therefore, it is important that the ovaries be examined during the first trimester with US scan. AUS scan is the first-line exam for the characterization of an ovarian mass. Pelvic MRI is useful during pregnancy in cases of uncertain diagnostics on US scans. It is the exam of choice when the pregnancy is advanced or when the tumor is large, as in our case [10]. The French recommendations for the management of ovarian masses and malignant tumors diagnosed during pregnancy allow us to propose management according to the diagnosis suspected on imaging and the term of the pregnancy, this is summarized in (Figs. 2) [10, 11, 15].
Figure 2: Suggested management strategy for ovarian mass discovery during pregnancy.
Of course, this management must be adapted according to the patient's age, the anatomopathological final diagnosis, the desire of future pregnancy and the current pregnancy. In the literature review, three cases of PMP were diagnosed before 28 weeks gestation. The other two cases were diagnosed at the time of Caesarean section [5, 6]. In E. Haase [4] and S. Koyama [8] cases, the pregnancy was continued until 34/35 weeks gestation where the risk to the premature infant is quite low. In the case of Sofia Jayi 2012 [7], the pregnancy was terminated at 20 weeks gestation to perform cytoreduction. It was patient wishes.
The prognosis of PMP depends on two main factors: the disease’s grade and the cytoreduction’s quality. The PMP can be classified as low grade or high grade PMP according to the 2010 WHO classification [1]. Low-grade appendicular PMP has a slower and less aggressive course than high-grade PMP [12, 13], with a better prognosis and a lower risk of recurrence. The low grade PMP natural history is very slow and progressive. For this reason, it seemed appropriate to induce delivery at 37 weeks gestation and wait 1 month postpartum before performing cytoreduction and HIPEC.
According to her, for high-grade PMP diagnoses at first or second gestation trimester the pregnancy termination must be considered. In the low-grade PMP because of the very slow progression disease, we can wait until 35 weeks whatever the diagnostic term. The delay in management induced by continued pregnancy certainly did not have a significant impact on the development of PMP. The PCI score in antepartum and postpartum remained quite the same (PCI at 21 in antepartum, without pelvis exploration, compared to 27 in postpartum after pouch of Douglas” +3, and left parametria peritoneum +2 exploration). Cytoreduction was macroscopically complete, which is the main prognostic factor. Finally, the 5-year survival of patients treated with cytoreduction and CHIP for low-grade PMP is 63%, compared with 23% for high grade PMP [12].
Pseudomyxoma peritonei in pregnancy is a diagnostic and management challenge. High clinical suspicion, careful imaging, and timely surgical intervention are crucial. This case adds to the limited body of literature and highlights the importance of considering rare diagnoses in atypical presentations.
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To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
