AUCTORES
Globalize your Research
Short Communication | DOI: https://doi.org/10.31579/2690-8808/225
*Corresponding Author: Leonchuk Sergey Lvovich, Clinical
Citation: Leonchuk Sergey Lvovich, (2024), On the Issue of the Nature and Definition of Depression, J, Clinical Case Reports and Studies, 5(9); DOI:10.31579/2690-8808/225
Copyright: ©, 2024, Leonchuk Sergey Lvovich. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 26 September 2024 | Accepted: 07 October 2024 | Published: 17 October 2024
Keywords: depression; adaptation; unresponsiveness
Currently, there is no common understanding of the nature of depression or its strict scientific definition, which leads to mistakes in the diagnosis and treatment of depressive conditions. The existing definitions of depression do not reflect its internal nature and are of an external descriptive nature, which leads away from the essence of the problem. The article offers the author's view on the nature of depression, as a state of ancient nonspecific adaptation - unresponsiveness, and gives its scientific definition.
The definition of scientific concepts is of great importance for the development of science. Their free interpretation leads away from the essence of the matter. The definition reflects the depth of knowledge of the subject. The development of science goes from one definition to another. Meanwhile, in scientific and practical Guides, little attention is often paid to the definitions of concepts; the definitions of concepts are vague and have a pseudo-scientific descriptive nature. WHO: Depression is persistent sadness, loss of interests, low self-esteem, feelings of guilt, and inability to do usual work. Wikipedia: Depression is a mental disorder, the main symptoms of which are low mood, anhedonia, feelings of melancholy, anxiety, and in severe cases - the depressive triad. In ICD-10, the diagnosis of depression is determined by a long list of typical clinical syndromes.
Currently, there is no common understanding of the nature of depression, which leads to errors in the diagnosis and treatment of depressive conditions. Some authors associate depression with hypothymia [12,13], others with a complex affective symptom complex [11], confirmed by path psychological research, and others - with phase protective states, complex neurobiological syndrome [1,3,4]. A number of authors propose more than 18 criteria for depression (Hamilton and Beck depression scales), which is labor-intensive and does not clarify the understanding of the phenomenology of depression. The neurotransmitter model of depression is simplified [14, 16], reveals its neurochemical mechanisms, but does not reflect its evolutionary path physiological essence. Meanwhile, any psychopathological phenomenon has its own phylogenetic basis, historical roots, and is a clinical expression of evolutionary processes, adaptation genesis, driven by natural selection, and not a simple consequence of dysfunction or breakdown of biological structures [16].
The binary (two-level) concept of depression is relevant, revealing the nature of depression, where negative affectivity in the form of alexithymia, anhedonia, dysphoria, anesthesia and apathy is primary, axial and reflects the nature, register of depression, and positive affectivity is secondary, reflecting reciprocal arousal adjacent to depressive focus of central structures [11]. With apathetic depression, there is no development of clinical depressive disorders, since apathy is the bottom of the depressive register disorders [11, 15]. Apathy is implied with abulia. The clinical picture of apathetic depression is reminiscent of apatoabulic syndrome in schizophrenia, but its dynamics are reversible, phase-specific. However, the outcome of long-term severe depression can be atrophy of depressive tissue, diseases of its disintegration, asthenic and somatoform syndromes, which expands the understanding of depressive disorders [11, 16].
In schizophrenia, the presence of apatoabulic syndrome indicates about the completion of the pathological process [7, 12, 13, 17]. It is also the bottom of negative register disorders, but is irreversible, has the character of a neuropsychic defect and has other pathogenetic roots. Apatoabulic states are a form of nonspecific adaptation of the body - unresponsiveness. The biological meaning of these conditions is to prevent disorganization and decay of the body under pathological conditions [7, 16, 17].
The aim of the article is to use the methods of scientific generalization, logic, systemic evolutionary analysis and theoretical modeling to understand the internal nature of depression and formulate its scientific definition. The relevance of the article is beyond doubt, because depression is widespread in the world and is a common cause of disability and mortality in the population.
An organism is an open biological system that expresses and preserves itself through the constancy of its internal environment, homeostasis. Regulation of homeostasis occurs at all its levels - cellular, tissue, systemic. Homeostasis is the moment of integrity and independence of the organism from the ecosystem, which dictates its morph functional structure through natural selection. Disruption of homeostasis is the essence of destruction and death. The organism, as a whole, a system, is formed through the reflection of internal needs and the reciprocal launch of self-regulation processes aimed at satisfying the reflected need, which leads to homeostasis and preservation of the body.
A cell is a biological system of a lower order. Cells are rigidly integrated into the macroorganism as an integral system, subject to its requirements, but have a certain independence, which ensures the plasticity and flexibility of its regulation.
Reactivity is the main property of life. Reactivity is the body’s ability to internally respond to changes in the demands of the ecosystem, the form of its interaction with it, a special type of reflection associated with the regulation of homeostasis.
The integrative factor of the life activity of a macroorganism, as a biological system of a higher order, is the reflected need, and the system-forming reactive structure is the basal nuclei of the brain and emotional centers [16].
The development of emotions comes from the reflex ring and the basal nuclei regulating homeostasis, working on the feedback principle [2]. Emotions, as a form of the psyche, reflect the body’s needs for matter, energy and information necessary to maintain homeostasis, and carry an energetic charge of self-regulation. Evolutionarily – genetically, according to the “stimulus-response” type, they are associated with effectors processes and form a single complex of the body’s reactivity with them. Emotions are the center of adaptive reactivity, goal setting and integration of the body. Being a system-forming reactive structure, they regulate in the body the movement of energy flows (metabolic, hormonal and vegetative) [16]. In humans, reactivity is differentiated, which is associated with the development of higher emotions, consciousness and intelligence.
The central nervous system has various adaptive energy modes of operation, which increases its functional plasticity. The energy regime is the ability of nervous tissue and the entire organism, as a whole system, to change the energy range of its functioning. Its change is observed with changes in motivation, biorhythms, and fluctuations in affect [6]. A low adaptive energy mode of the body's vital activity with an increase in the threshold of its reactivity is postulated as depression.
The equivalents of depression, like the equivalents of other clinical phenomena, are projected into the animal world, for nothing arises from nothing, and each clinical phenomenon has its own evolutionary history. It is known that higher mammals often suffer from typical types of depression. In lower animals, states of unresponsiveness—anabiosis—are observed. If we draw well-known physiological parallels, then depression is the equivalent of suspended animation. Ancient adaptations do not disappear in the process of evolution, but are suppressed and appropriated by new young adaptations, acquiring a different internal content.
Central adaptive mechanisms for regulating the reactivity of the body operate at all its levels - cellular, tissue, systemic, but autonomous regulation of reactivity is also possible. The cell, being a lower-order biological system, can exhibit the capabilities of autonomous parafunctional regulation when the central regulation of the body is weakened [16].
Adaptation can be specific or nonspecific [10]. Nonspecific adaptation is associated with ancient generalized undifferentiated defense mechanisms: hyperthermia, phagocytosis, general adaptation syndrome, suspended animation, muscle numbness, psychomotor agitation, blackout, autism, trance, pain. The evolution of the living world follows the path of creating differentiated protection associated with the development of higher forms of neuropsychic activity. However, the ancient adaptive regulations of the organism do not disappear during the process of evolution, but are suppressed and appropriated by new young forms. When phylogenetically young functions are damaged, ancient relationships begin to manifest themselves. In the dynamics of the body's reactions to damaging factors, one should see not arbitrary dysfunctions and broken structures, but a natural retreat of the body to past stages of development with the exposure of ancient defense mechanisms. The plasticity of the body's regulation lies in the fact that when it is difficult to manifest new specific functions, nonspecific relationships again appear on the scene. When homeostatic systems are weakened and internal constants change, the body's cells begin to find themselves in harsh survival conditions; Young specialized brain structures responsible for specific adaptation are especially affected. As a result, the mechanisms of ancient nonspecific adaptation again come to the fore. Ancient adaptive nonspecific regulations of the body continue to operate at higher stages of evolution of the living world, but in the form of their equivalents [16]
Anabiosis is a form of ancient nonspecific adaptation, consisting in the body's unresponsiveness; common in viruses, bacteria, worms, fish, amphibians, and reptiles. In some higher animals (bears, badgers, rodents) it is seasonal, observed in the form of periods of hibernation. As an equivalent, suspended animation can be observed in humans in the form of Seasonal Affective Disorder.
Depression is a state of unresponsiveness, adaptive suppression of vital processes, a low adaptive energy mode of functioning of the body in order to preserve its internal organization in conditions of pathology. Depression is a form of ancient nonspecific adaptation, the equivalent of suspended animation, provides time for rest, restoration of impaired functions, and reflects plasticity and flexibility of regulation [16].
Depressive tissue is a pathological tissue in which protective inhibition of vital processes, a low adaptive energy mode of functioning, an adaptive increase in the threshold of reactivity, and systemic disintegration are observed in order to prevent its disorganization and decay in pathological conditions.
It is known that in the presence of central depression, neuropsychiatric disorders have a benign course (TBI, encephalitis, stroke, schizophrenia, Alzheimer's disease, Parkinson's disease, etc.) in contrast to lucid states. Depression acts as a biological defense factor. It is likely that somatic diseases in the presence of autonomic depression also have a benign course.
The regulation of the body's reactivity is associated with the regulation of the energy modes of its functioning. A low energy mode of life with an increase in the threshold of the body's reactivity is postulated as endogenous depression.
The following types of regulation can be distinguished [16]:
A. Central regulation of the body’s reactivity:
1. Cyclic form - ancient, associated with the basal structures of the brain, nonspecific generalized adaptation, reflecting natural cycles and rhythms.
With depression, disturbances in the rhythmic functioning of the hypothalamic-pituitary and limbic systems are observed and pineal gland, which manifests itself in the rhythm of release of releasing hormones and melatonin. This form of regulation is associated with daylight photons, which affects the total rhythm of the body, including the rhythms of wakefulness and sleep, sexual activity and food intake [8]. The cyclic form of regulation of the body's reactivity is generalized and nonspecific. In the pathology of the cyclic form of regulation, bipolar affective disorder with a clinical picture of negative affectivity is observed. There are no symptoms of positive affectivity due to the systemic, generalized nature of depression.
2. Affective form – phylogenetically younger emotional regulation of reactivity, dictated by the action of the environment and reflected need. The progressive evolution of the body's reactivity consists in the development of differentiation of basic emotions. Emotions, reflecting current needs and being the system-forming reactive center of the body, regulate the energy regimes of its life activity. The affective form of regulation of reactivity is partial and specific. In pathology of the affective form of regulation, a recurrent affective disorder with a negative clinical picture is observed and positive affectivity.
B. Autonomous regulation of reactivity.
When the central regulation of the body is weakened, peripheral cells and tissues of the body can exhibit the possibility of autonomous, parafunctional regulation. In the clinical picture of autonomic depression, adaptive inhibition of the functions of pathological tissue, its systemic disintegration and systemic compensatory processes are observed.
It is necessary to differentiate between central depression and hypothymia. Depression is the unresponsiveness of the soil on which the pathological process grows; it is deep and necessary, has the character of a condition and is associated with the central regulation of reactivity. Hypothymia is superficial, random and transient; it is not a condition of adaptive soil movement. Depression is treated with biological methods, hypothymia – with psychotherapy [9].
The distinction between neurotic, including tearful depression, is hardly justified, since tears are a form of relieving neuropsychic tension during fear and its clinical equivalents - anger, anxiety, stress and physical pain [18]. Patients with depression note "dry tears" and lack of tension relief. Tearfulness is usually found in the structure of astheno-neurotic syndrome, depression belongs to a deeper register of neuropsychic disorders.
The regulation of the body's reactivity is associated with the regulation of the energy regimes of its life activity. A low adaptive energy mode of the body's vital activity with an increase in the threshold of its reactivity is postulated as depression.
Depression is a state of unresponsiveness, adaptive suppression of vital processes, a low adaptive energy mode of functioning of the body in order to preserve its internal organization in conditions of pathology. Depression is a form of ancient nonspecific adaptation, the equivalent of suspended animation, provides time for rest, restoration of impaired functions, and reflects plasticity and flexibility of regulation.
The cyclic form of regulation of the body's reactivity is generalized and nonspecific. In its pathology, bipolar affective disorder is observed with symptoms of negative affectivity, which are primary, axial and reflect the internal nature, the register of depression. At the same time, secondary positive affectivity is not observed due to the systemic, generalized nature of depression.
The affective form of regulation of the body's reactivity is partial and specific. In its pathology, recurrent affective disorder is observed with symptoms of negative and positive affectivity. At the same time, positive symptoms of depression are not obligate, but are a consequence of reciprocal excitation of central structures adjacent to the depressive focus with phenomena of secondary hyperesthesia.
With autonomous depression, adaptive inhibition of the functions of pathological tissue, its systemic disintegration, and systemic compensatory processes are observed.
There is no conflict of interest.
The article was written without sponsorship.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
