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Research Article | DOI: https://doi.org/10.31579/2693-2156/136
*Corresponding Author: Elizaveta I Bon, Candidate of biological science, Assistant professor of pathophysiology department named D. A. Maslakov, Grodno State Medical University, 80 Gorky St,230009, Grodno, Belarus.
Citation: Bon E.I, Maksimovich N.Ye, Kazlouski D.А (2025), Neuroses in Children, J Thoracic Disease and Cardiothoracic Surgery, 6(4); DOI:10.31579/2693-2156/136
Copyright: © 2025, Elizaveta I Bon. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 10 June 2025 | Accepted: 24 June 2025 | Published: 08 July 2025
Keywords: neurosis; psychotic phenomena; emotional-affective; somatovegetative disorders
Purpose of the work: to analyze the characteristics of neuroses in children, identify their main symptoms and study the factors influencing their occurrence
Neurosis is a psychogenic (usually conflictogenic) neuropsychiatric disorder that occurs as a result of disruption of particularly significant life relationships of a person and manifests itself in specific clinical phenomena in the absence of psychotic phenomena.
Neurosis is characterized by: reversibility of pathological disorders, regardless of its duration; psychogenic nature of the disease, which is determined by the existence of a meaningful connection between the clinical picture of neurosis, the characteristics of the relationship system and the pathogenic conflict situation of the patient; specificity of clinical manifestations, consisting in the dominance of emotional-affective and somatovegetative disorders.
What is neurosis?
Neurosis is a psychogenic (usually conflictogenic) neuropsychiatric disorder that occurs as a result of disruption of particularly significant life relationships of a person and manifests itself in specific clinical phenomena in the absence of psychotic phenomena.
Neurosis is characterized by: reversibility of pathological disorders, regardless of its duration; • psychogenic nature of the disease, which is determined by the existence of a meaningful connection between the clinical picture of neurosis, the characteristics of the relationship system and the pathogenic conflict situation of the patient; • specificity of clinical manifestations, consisting in the dominance of emotional-affective and somatovegetative disorders.
Currently, the concepts of polyfactorial etiology of neuroses are most widely used in world literature. The unity of biological, psychological and social mechanisms is recognized. When assessing the role of a particular etiological factor in neuroses, significant difficulties arise.
Psychotraumatization is the leading cause of neurosis, but its pathogenic significance is determined by the most complex relationships with many other predisposing conditions (genetically determined "soil" and "acquir ed predisposition"), which are the result of a person's entire life, the history of the formation of his body and personality. It is difficult to take into account all the congenital and lifetime circumstances, to obtain valid data, because for this it is necessary to compare with similar characteristics in healthy people. In addition, in the origin of neurosis in a particular patient, the ratio of etiological factors has a unique peculiarity, and averaging etiological indicators often leads to the opposite result. Neuroses can occur in people who do not suffer from psychopathies, as well as without psychopathic character traits. One of the main etiological factors of a social nature is improper upbringing in the family. Patients with hysterical neurosis were characterized by an atmosphere of pampering, fawning upbringing, unprincipled compliance with the patient, unjustified emphasis on existing and non-existent virtues, positive qualities, which leads to to an inadequate overestimation of the level of aspirations. Character traits inherent in hysteria can be formed, on the other hand, with an indifferent attitude of the "rejection" type, as well as in an environment of crudely despotic suppressive education. The formation of personality traits predisposing to the development of obsessive-compulsive neurosis is facilitated by improper education in an environment of excessive care, protection, intimidation, suppression of independence and deprivation of one's own initiative. Of particular importance is the presentation of contradictory demands. In the genesis of psychogenic disorders, a special place is occupied by psychological conflict (external or internal), the pathogenicity of which is due to the patient's inability to resolve it. External conflict is determined by the clash of disturbed relationships of the individual with the demands of the environment. Internal (intrapersonal) conflict is determined by the existence of contradictory desires, tendencies, motives and positions of the individual.Hysterical conflict is determined primarily by excessively inflated claims of the individual, combined with underestimation or complete disregard for objective real conditions or demands of others. It is distinguished by an excess of demands on others over demands on oneself and a lack of critical attitude to one's behavior. Due to improper upbringing, such individuals have a weakened ability to inhibit their desires that contradict social demands and norms. The obsessive-psychasthenic type of neurotic conflict is caused primarily by contradictory internal tendencies and needs, the struggle between desire and duty, between moral principles and personal attachments. At the same time, even if one of them becomes dominant, but continues to meet resistance from the other, favorable opportunities are created for a sharp increase in neuropsychic tension and the emergence of obsessive-compulsive neurosis.
Of particular importance is the presentation of contradictory demands on the individual, which contributes to the formation of a sense of inferiority, contradictory life relationships and leads to a break from life, the emergence of unrealistic, unrealistic attitudes
The neurasthenic type of conflict is a contradiction between the capabilities of the individual, on the one hand, his aspirations and inflated demands on himself, on the other. The specified types of neurotic conflicts to a certain extent correspond to three main forms - hysteria, obsessive- compulsive disorder and neurasthenia. Patients with neuroses are characterized by such personality traits as weakness, indecisiveness, a tendency to reflection, dependence on the environment, the search for approval, the desire for normativity.
A patient with neurosis is characterized not by the presence of one or two leading, most significant conflicts, but by the existence of a wide range of them, caused by disturbances in the system of relationships, among which an emotionally unfavorable, inadequate attitude towards oneself acts as the most pathogenic, causing many subjectively unresolvable contradictions. It is possible to identify personality disorders common to patients with neuroses, among which infantile and egocentric traits are the main ones and determine the emotional, behavioral and social deficits of the personality of a patient with neurosis. The relationship between a doctor and a patient with neurosis has certain characteristics depending on the methods of treatment used.
Types of neuroses:
Neurasthenia.
The word "asthenia" in Greek means "impotence, weakness". Asthenia is understood as pathological fatigue after normal activity, accompanied by a decrease in energy, which is necessary to ensure normal life and attention, a sharp decrease in performance. Asthenia is usually accompanied by lethargy, drowsiness, irritability; a feeling of fatigue and exhaustion prevails.
The main symptom of neurasthenia is irritable weakness, i.e., increased excitability and easy exhaustion. Asthenic complaints proper (general weakness, fatigue, exhaustion, lethargy, daytime sleepiness) are combined with headaches, attention and memory impairment. These complaints do not go away after rest. In addition, children often suffer from various sleep disorders: difficulty falling asleep, superficial and restless sleep with an abundance of dreams, easy awakening under the influence of minor external stimuli.
Anxiety-phobic disorders.
Anxiety is an emotional state characterized by strong negative affect, symptoms of muscle tension, and a premonition of danger or failure in the future. This definition includes two main signs of anxiety: strong negative emotions and an element of fear. Neurotic phobias are an obsessive experience of fear with a clear plot in the presence of sufficient criticism. They are exacerbated in certain situations and are vivid, figurative, and sensory in nature.
In preschool and primary school age, anxiety disorder associated with separation anxiety in childhood is common. It manifests itself in excessive anxiety that is inappropriate for development, associated with being outside the home or with the fear of separation from parents and other people to whom the child is attached, as well as in a constant reluctance (refusal) to go to school or go anywhere from home for fear of being separated from loved ones. The child experiences persistent and excessive anxiety about the possible loss of people to whom he or she is strongly attached, or about an expected accident with them, and does not want to go to bed if they are not nearby. The reason for visiting a doctor is often complaints of malaise (headache, stomach ache, etc.), as well as the appearance of nausea or vomiting when separation from loved ones occurs or is expected. If the child refuses to go to school or leaves lessons, then later the child often develops “test anxiety” - strong experiences in situations where knowledge is tested (tests, exams).
Children with generalized anxiety disorder experience chronic or excessive anxiety and emotional tension, which are often accompanied by somatic symptoms.
Children with specific phobias are characterized by strong fear associated with certain objects or situations (fear of heights, vaccinations, spiders, etc.). Anxiety can be expressed in crying, whims, freezing in place, seeking protection from adults. Specific phobias can develop at any age, but most often occur in children aged 10-13. Phobias associated with animals, darkness, insects, blood, and injuries usually appear between the ages of 7 and 9, making them similar to fears characteristic of normal development. Like normal fears, clinical phobias weaken over time, but, unlike fears, phobias tend to persist for a much longer period of time. Symptoms of social phobia include fear of speaking in public, blushing, excessive anxiety about actions and deeds, and extreme shyness.
Obsessive-compulsive disorder
Obsessive-compulsive disorder is characterized by the appearance of obsessive thoughts and ritualistic behavior. Obsessions are persistent, intrusive, and irrational thoughts, ideas, impulses, or images. The most common obsessions in children are fear of contamination and fear of harming themselves or others.
Research on children's mental health problems
Studies of Child Mental Health Problems There is growing interest in child and adolescent mental health problems [1]. Mental disorders affect a significantly higher proportion of children and adolescents in the child welfare system than in the general population. A pooled prevalence of 49% for any mental disorder has been estimated using meta-analysis [2]. In the United States, 43,283 parents of children aged 3 to 17 years responded to a national survey that found that 7.4% of the children had current conduct problems, 7.1% had current anxiety problems, and 3.2% had current depression [3]. The survey, which relied on parent reports, estimated that the prevalence of anxiety or depression among children aged 6 to 17 years increased from 5.4% in 2003 to 8.4% in 2011–12 [4]. Based on a meta-analysis report summarizing the prevalence of common mental disorders among adolescents aged 10 to 19 years, the global prevalence of common mental disorders measured by the 12-item General Health Questionnaire with cut-off points of 4 and 3 were 25% and 31%, respectively [5]. The Seoul Child and Adolescent Mental Health Survey reported the estimated prevalence of full syndrome and subthreshold Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) disorders as 16.2% and 28.1%, respectively [6]. Interestingly, the prevalence rate of mental disorders estimated through epidemiological studies and the diagnostic prevalence rate observed in clinical practice may differ. The prevalence rate of mental disorder diagnosis was found to be 1.95–2.38
During the study period, gender, grade, and diagnosis were retrospectively analyzed using the medical records of first-time patients by year. To analyze the factors affecting treatment continuity, participants with fewer than three outpatient visits were classified as the early dropout group, while participants with three or more outpatient visits were considered as the treatment continuity group; this was based on a study on early dropout factors [11]. Patients were diagnosed by child psychiatrists and a clinical psychologist using the Korean Standard Classification of Diseases (KCD) [12], which is based on the International Classification of Diseases [13].
Age groups were analyzed using three-year intervals (grades 1–3, 4–6, 7–9, 10–12) based on a previous study reporting the prevalence of mental disorder diagnoses in the 0–18-year-old age group [7].
To compensate for the limitations of individual hospital data, the diagnostic rates for the entire population were calculated by reflecting the total population at mid-year [14]. In other words, the clinical diagnosis of mental disorders was analyzed based on the total population aged 6–18 years per year.
The KCD codes for diagnosis were limited to mental disorders, symptoms and signs, abnormal clinical and laboratory findings not elsewhere classified, and factors affecting health status and contact with health services. For mental disorders, six higher diagnostic groups were established in order of frequency based on sample data from the HIRA study [9] and a preliminary analysis of these data. Hyperkinetic disorders (F90) and tic disorders (F95) were assigned to the same diagnostic group. The remaining four diagnosis groups were classified together with related disorders: neurotic disorders (F40–48), depressive disorders (F32, 33), disruptive behaviour disorders (F91–94), and mental retardation (F70–79). Disorders that affect a small number of patients were classified as 'other', which included the following diagnoses: psychotic disorders (F20–29), bipolar disorders (F30, 31), eating and sleep disorders (F50, 51), personality disorders (F60–65), learning and developmental disorders (F80–84), and unspecified mental disorder (F99). The per-person diagnosis analysis allowed for redundancy.
Statistical analysis
Changes in the prevalence of mental disorders from 2009 to 2016 by gender, grade, and year were examined according to the rate of increase or decrease in the average annual rate, and the significance of trends was assessed using a trend test. The prevalence rate was converted to the percentage of F codes diagnosed by psychiatrists per 100,000 population included in each group, as indicated by the general population at mid-year.
To examine factors affecting continuity of care, patients were divided into groups based on the number of outpatient visits, and the best-fit logistic regression model was selected using a stepwise method based on gender, grade, implied diagnosis, and number of excess diagnoses. A generalized linear model with an interaction term for year and grade was estimated to compare the annual growth rate of each class by gender.
Statistical significance was set at 0.05 for all analyses and data were analyzed using R 4.0.2 in SAS 9.4 (Statistical Analysis System version 9.4, SAS Institute, Cary, NC, USA).
Of the 1467 participants, 931 (63.5%) were male and 536 (36.5%) were female. Between 2009 and 2016, the overall number of cases per 100,000 population by age group (6–18 years) significantly decreased from 3.24 to 1.88, and the number of male patients significantly decreased from 4.14 to 2.03. The number of female patients decreased from 2.24 to 1.72, which was not statistically significant. The overall ratio of male to female patients decreased from 1.87 to 1.29 during the study period, which was not statistically significant. In the overall distribution of participants by class, the highest proportion of patients was in classes 1–3. In terms of annual changes, the changes in classes 1–3 were higher than in other classes in 2009, 2011, and 2013, and the changes in classes 10–12 were higher than in other classes in 2010, 2012, and 2014– 2016. The number of males decreased significantly in classes 1–3, 7–9, and 10–12. The number of females showed a significant decrease in classes 4–6 and 7–9. Using a generalized linear model with year and grade as interaction terms, the number of female participants in grades 10–12 showed a significant increase compared to participants in grades 1–3. In terms of the distribution of diagnostic codes in male participants, hyperkinetic disorders (F90) were the highest, followed by neurotic disorders (F40–48), tic disorders (F95), psychotic disorders (F20–29), bipolar disorders (F30, 31), eating and sleep disorders (F50, 51), personality disorders (F60–69), specific developmental disorders of speech and language (F80), specific developmental disorders of scholastic skills (F81), pervasive developmental disorders (F84), unspecified mental disorder (F99), intellectual disability (F70–79), depressive disorders (F32, 33), and disorders disruptive behavior (F91–94). F90 had the highest diagnostic rate during the data collection period, but this has been declining. F91–94 diagnoses have decreased significantly with each passing year. In women, the diagnostic distribution was F40–48, F90, F32, F33, other, F70–79, F95, and F91–94. The most common single diagnosis in women was other anxiety disorders (F41), followed by depressive episodes (F32), somatoform disorders (F45), and F90. F70–79 diagnoses have decreased significantly with each passing year.
Discussion
In this study, a significant decrease in the total number of newly diagnosed patients and male patients was observed even when the statistics were adjusted for the declining birth rate in the Republic of Korea. These results are consistent with the decreasing prevalence of mental disorder diagnosis in children and adolescents aged 0–19 years reflected in the HIRA statistics [7]. These trends are in contrast to the increasing prevalence of mental disorders in children and adolescents in screening-oriented epidemiological studies [15]. This suggests that there may be differences in the estimated prevalence and diagnosis rates in clinical practice depending on the epidemiological study methods or national health systems. Two factors may have influenced this trend: first, the Adolescent Personality and Mental Health Problems Screening Questionnaire, which has been administered to 1st, 4th, 7th, and 10th grade students nationwide in the Republic of Korea annually since 2012 and the increased number of treatment-related cases; Secondly, the awareness of parents about mental disorders in young people through mass media or public education [1]. The gender ratio of mental disorders changes during the transition from childhood to adulthood due to biological and environmental factors. According to the 2011 HIRA data, in a population study of under 19 years old, the ratio of males to females with mental disorders was
1.68:1 [16]. This study also showed that the percentage of male patients was higher than the percentage of female patients. The HIRA sample data of 1,375,842 individuals in 2011 showed that the ratio of males to females in 19–30 years old was 48.1 to 51.9 [17]. A cross-national meta- analysis of mental disorders in the World Health Organization World Mental Health Surveys also showed that the prevalence of mental disorders was 1.1 times higher in females than in males [18]. The reason for this change in gender ratio should be noted here. One of the reasons for such a significant narrowing of the gender difference was related to depressive disorders and changing traditionalism of gender roles [18].
In this study, the number of male patients from grades 1 to 12 and female patients from grades 1 to 9 decreased. Interestingly, the increase in the number of female patients in grades 10–12 was statistically significant compared to other grades when the number of patients in grades 1–3 was the reference, although the increase in the number of female patients in grades 10–12 per year was not statistically significant. One of the factors contributing to the trend observed in this study was the different distribution of mental disorders in female patients compared to males. The most common diagnosis in female patients in this study was F41, followed by F32, F45, and F90. The lifetime diagnosis of anxiety or depression among children aged 6 to 17 years has increased based on a survey of parents in the United States [4]. While current anxiety increased significantly, current depression did not change. In a study on the prevalence of childhood mental disorders in Taiwan, anxiety disorder had the highest lifetime prevalence, followed by ADHD, sleep disorder, and tic disorders [19]. Comorbidity and homotypic and heterotypic continuity from ages 9 to 16 were more pronounced in girls than in boys, and girls had a higher incidence of depressive disorders as they grew older [20]. In Kim’s study [21], the number of patients in grades 1–3 was higher than in any other grade from 2004 to 2009, and in grades 10–12 was higher than in any other grade from 2010 to 2013. During this period, the incidence of depressive disorders increased among grades 7–12.
The most common diagnosis in male patients in this study was F90. One of the reasons why the class 1–3 group is larger than other classes in the psychiatric outpatient clinic may be that this group has a higher diagnosis and treatment rate of patients with ADHD [7]. From three population cohorts and a meta-analysis, it is evident that children and adolescents who are relatively younger than their classmates have a higher risk of being diagnosed with ADHD [22]. According to the Centers for Disease Control and Prevention in the United States, ADHD was the most common mental disorder among children under 18 years of age [23]. ADHD was the most common mental disorder among the population under 19 years of age based on the HIRA sample data, followed by other anxiety disorders (F41), depressive episodes (F32), somatoform disorders (F45), reaction to severe stress, and adjustment disorders (F43) [16]. A longitudinal comparison over a 26-year period (1980–2005) in a tertiary care centre for child and adolescent psychiatric services in India found an increase in the reporting of affective illnesses at ages 10–15 years, reflecting the global trend towards earlier onset and increasing prevalence of affective illnesses [24]. In a study of the prevalence of common mental disorders among adolescents over three consecutive years in Taiwan, rates of ADHD and phobias decreased, while rates of major depression and substance use disorders increased [25]. Conduct disorder and ADHD were more common among boys, while major depression and phobias were higher among girls.
A significant decrease in F91–94 was observed among male patients over the years, while F70–79 showed a decreasing trend in female patients in this study. A comparison of clinical profiles of patients in child psychiatry in Bahrain between 1981–82 and 2011–12 showed that the prevalence of conduct disorder and anxiety disorders was lower [26]. The reason for this decrease in prevalence is most likely due to reasons other than a real decrease, such as those diagnosed with ADHD or learning disorders instead of conduct disorder. In this study, if conduct disorder and ADHD coexisted in the same patient, they could be diagnosed with ADHD. The prevalence of conduct disorder also decreased between 1998 and 2013–14 among young men, according to a study in Australia, primarily due to a decrease in prevalence among men living in two-parent families [27]. The significant decrease in F70–79 may be due to earlier identification and intervention among individuals with intellectual disabilities in the preschool years compared to the past, resulting in improved adaptability [16]. However, the reason for the significant decrease only among women in this study should be investigated in future studies. In this study, significant factors for treatment continuity were female, higher grades, one or more clinical diagnoses, and disorders such as depressive disorders, hyperkinetic disorders, and tic disorders. One of the reasons influencing treatment continuity among those in higher grades and among women may be the increased anxiety and depressive disorders in the respective gender and age group [9]. A study based on inpatient adolescents showed that being female predicted change in global functioning [28]. Pelkonen et al. [11] also reported that the absence of a mood disorder and non- use of psychotropic medications were associated with early dropout from outpatient psychiatric treatment in adolescents. The younger the patients, the more likely they were to drop out of the study early without starting pharmacotherapy for ADHD [29]. Young children are at higher risk of receiving suboptimal care with psychotropic medications [30], and their treatment adherence may be reduced by their parents' adherence [31]. These findings suggest that factors in treatment adherence may differ depending on target disorders, culture, age and gender of subjects, or study design.
This study has several limitations. First, as a descriptive study, the results and conclusions are limited to this sample. The participants in this study are outpatients of a single university hospital, and caution should be exercised in applying the results of this study to the entire general population. However, since it is based on the medical records of the same medical staff at a single institution, consistency in care may be an advantage.
Second, this study is a retrospective review of medical records and does not administer planned diagnostic instruments as in prospective studies. Therefore, it has limitations in application and difficulty in determining the causes of the results. In the future, it may be better to conduct a prospective study to estimate prevalence. Although this study adopted a retrospective perspective, the fact that the same child psychiatrists and the same clinical psychologist performed the diagnostic procedures also provides the advantage of increasing diagnostic accuracy and consistency.
Third, the results may reflect some bias. It is possible that patients referred to a university hospital psychiatric clinic have more severe symptoms or other associated characteristics than those who do not require a university hospital clinic. Moreover, such patients may be more likely to have pre- existing psychiatric disorders due to referral bias.
Despite these limitations, this is the first study in Korea in which trends among outpatients were verified by reflecting changes in the general population. Identifying predictors of treatment continuity in first-time patients is also a strength of this study. The study is meaningful because patients with treatment continuity were followed for approximately eight years in the same outpatient clinic.
To overcome these limitations and apply the results of this study to extrapolate mental health problems to the general child and adolescent population, follow-up studies involving other university hospitals and private clinics are needed.
Treatment of neuroses
Sedatives and tranquilizers are used to treat neuroses in children. The former include herbal preparations based on valerian, lemon balm, St. John's wort: Dormiplant, Gelarium Hypericum, etc. The group of tranquilizers (anxiolytics) includes psychopharmacological agents that reduce manifestations of anxiety, emotional tension, and fears. In addition, tranquilizers are characterized
by hypnotic, anticonvulsant, and muscle relaxant effects. In the treatment of neuroses in children, it is advisable to use non-benzodiazepine tranquilizers (Phenibut, Tenoten, Atarax), since they have fewer side effects. One of such drugs is Adaptol. Adaptol can have a metabolic effect, normalizing metabolic processes disrupted by stress, and also affect the functioning of neurotransmitter systems. According to the literature, Adaptol exhibits antagonistic activity in relation to the excitatory adrenergic and glutamatergic systems and enhances the functioning of the inhibitory serotonin- and GABA-ergic mechanisms of the brain. It has moderate anxiolytic activity, eliminates or reduces anxiety, anxiety, fear, internal emotional stress and irritability. The tranquilizing effect of the drug is not accompanied by muscle relaxation and impaired coordination of movements. Adaptol does not cause emotional dullness, deterioration of attention and memory, inhibition, muscle relaxation, drowsiness, etc. The drug has a dopamine-positive effect, clinically manifested in its activating component of action, which is very important in the treatment of neurasthenia. Based on this, it is classified as a daytime tranquilizer. In addition, Adaptol is characterized by a nootropic effect. The drug is prescribed to children aged 5–7 years at a dose of 0.5 g/day, 7–10 years — 0.75 g/day, 10–14 years — 1.0 g/day, 14 years and older — 1–1.5 g/day in 2–3 doses. The course of treatment is 1–2 months, but improvement can be observed already in the 1st week of therapy.
Recommendations for the prevention of neuroses in children
Do not focus on the child's weaknesses and help him develop those good and respectable qualities. The girl is not a beauty? So what, but what a smile she has, how sociable, kind and smart she is. You cannot get by with general phrases like "this is not the main thing" when talking about a child's shortcomings, be sure to provide some of his real positive qualities as an alternative.
Try to be objective about the child and form a healthy attitude towards himself. Do not attribute non-existent qualities to him, do not praise him for what the parent wants to see and certainly do not scold him for "not wanting" to do what the parents think he is capable of. But do not keep silent about the merits - any talent of the child is valuable and only life will show which of them was the most important.
Develop social behavior skills in the child. It is necessary to teach the child the rituals of greeting, farewell, and introduction accepted in society, not to allow the child to be ignored or alienated, to ensure that the child is sufficiently informed - in order to communicate with others, it is necessary to have common topics for discussion with them.
Do not allow manifestations of overprotection. Only if you give the child the opportunity for independence - within reasonable limits, of course - will he take advantage of this opportunity.
To sum up, we can say with confidence that neurosis does not occur in self-confident people, in those prepared for real life, in those who are able to adapt to life normally and with dignity, and most importantly, in people who are devoid of egocentrism. A child should love himself, some egoism is natural in him, but he should also love his environment - mom, dad, friends, city, nature, his daily activities,
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"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
