Mediation of Executive Functions in the relationship between Internet Addiction and Early Maladaptive Schemas among Iranian university students: A structural equation modeling approach

Review Article | DOI: https://doi.org/10.31579/2767-7370/123

Mediation of Executive Functions in the relationship between Internet Addiction and Early Maladaptive Schemas among Iranian university students: A structural equation modeling approach

  • Soosan Mohammadkhah 1*
  • Elham Taheri 2
  • Maedeh Kamrani 3
  • Azadeh Saki 4

1 M.Sc. Student in Clinical Psychology, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
2 Assistant Professor, Department of Clinical Psychology, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
3 Assistant professor of psychiatry, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Associate Professor, Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

*Corresponding Author: Soosan Mohammadkhah, Ege University, School of Physical Education and Sports, Faculty Member.

Citation: Soosan Mohammadkhah, Elham Taheri, Maedeh Kamrani, Azadeh Saki, (2025), Mediation of Executive Functions in the relationship between Internet Addiction and Early Maladaptive Schemas among Iranian university students: A structural equation modeling approach, J New Medical Innovations and Research, 6(1); DOI:10.31579/2767-7370/123

Copyright: © 2025, Soosan Mohammadkhah. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 20 December 2024 | Accepted: 26 December 2024 | Published: 20 January 2025

Keywords: internet addiction; early maladaptive schemas; executive functions

Abstract

Internet Addiction is a global public health issue among university students that is associated with a range of negative outcomes. Although previous studies have indicated that the Early Maladaptive Schemas have important effects on Internet Addiction, the mechanisms underlying these associations are still unclear. To fill this gap in the literature, this study investigated the mediating role of Executive Functions in the association between Early Maladaptive Schemas and Internet Addiction following the Interaction of Person-Affect-Cognition-Execution model. The data were collected from 826 university students aged 18 to 30 years. Using structural equation modeling, it was found that schemas of the domains of disconnection/rejection, impaired autonomy/performance, and impaired limits had a significant relationship with Internet Addiction both directly and indirectly through executive functions. While other-directedness domain schemas were only directly associated to Internet Addiction. The study’s findings provide new insight into the development of specific psychological approaches aimed at preventing and treating Internet Addiction

Abbreviations

IA: Internet addiction
I-PACE: Interaction of Person-Affect-Cognition-Execution
EFs: Executive Functions
EMSs: Early Maladaptive Schemas
CFA: Confirmatory Factor Analysis
SEM: Structural Equation Modeling
VIF: Variance Inflation Factor
ω: McDonald’s Omega Coefficient
α: Cronbach’s Alpha Coefficient
AVE: Average Variance Extracted
HTMT: Heterotrait-Monotrait Ratio
CI: Confidence Interval
CMIN/DF:Chi-square to Degrees of Freedom Ratio
GFI: Goodness of Fit Index
CFI: Comparative Fit Index
TLI: Tucker-Lewis Index
RMSEA: Root Mean Square Error of Approximation
SRMR: Standardized Root Mean Square Residual

Introduction

During the past two decades, with the rapid development of information technology, access to the Internet has become more widespread and has revolutionized the way individuals communicate with each other. Furthermore, it has become an integral, popular, and essential part of many individuals’ daily lives [1, 2]. More than 66% of all the people on Earth now use the Internet, with the latest data putting the global user total at 5.35 billion [3]. Internet usage in developing countries has also increased from 7.7% to 45.3

Method

2.1. Data collection procedure

The data were collected as part of an unpublished master’s thesis by the first author, supervised by the second author [61]. The study design was cross-sectional, and a combination of random multi-stage cluster and convenience sampling methods was used to collect the data. The data were collected between October 2023 and April 2024, using printed surveys in Persian. The study’s participants were 18- to 30-year-old university students from Tehran, Iran. Data collection took place at universities under the supervision of researchers and their assistants, and on average, it took about 25 min to answer the questionnaires. Participation in the survey was voluntary and anonymous and could be canceled at any time. No personal information was collected. Informed consent was required. First, the participants were informed of the objectives and scope of the study, and confidentiality was also guaranteed. All participants were then asked to indicate that they agreed to participate in the study and to use the data for scientific purposes. Incentives were also used to increase participation (Five 10,000,000 IRR credit gift cards were raffled among respondents, each being worth about 25 USD). The study was conducted following the principles of the Declaration of Helsinki and ethical approval was obtained from the Ethics Committee of Mashhad University of Medical Sciences, Iran (Reference IR.MUMS.MEDICAL.REC.1402.238).

2.2. Participant

The participants were recruited from the selected classes of 10 randomly selected universities using convenience sampling. These classes were chosen through a random multi-stage cluster sampling process, and within each class, participants were recruited using convenience sampling. A total of 1100 surveys were completed by the participants. After excluding 274 surveys (208 surveys that were not fully answered, 57 surveys that showed excessively patterned responses, and 9 surveys that were identified as multivariate outliers), the final sample for data analysis consisted of 826 valid surveys, meeting the requirements for structural equation modeling [62]. Of the 826 respondents, 15.3% were males and 84.7% were females, whose age range was 18-30 years (M =22.79, SD =3.28). Regarding education level, most participants had a bachelor’s degree (81.96%), 15.98% had a master’s degree, and 2.06% had a doctoral degree. Regarding marital status, 24.5% of the participants were married and 75.5% were single.Finally, regarding employment status, 50.8% of the participants were employed, while 49.2% were unemployed.

2.3. Measures

2.3.1. Young Schema Questionnaire-Short Form (YSQ-SF)

The Young Schema Questionnaire-Short Form was utilized to evaluate EMSs. This questionnaire is a self-report measure with 75 items developed to assess the presence of 15 different EMSs in 5 domains, with 5 items per EMS [63]. Some examples of items are as follows: "For much of my life, I haven’t felt that I am special to someone, I worry about being attacked, and I have rarely been able to stick to my resolutions". Items are scored on a 6-point Likert scale ranging from 1 (Completely untrue of me) to 6 (Describes me perfectly). Each EMS is scored by summing the responses to its corresponding items, ranging from 5 to 30, with higher scores representing a greater possibility of the presence of that EMS for that individual. In this study, we obtain the total score of each domain by summing the scores of its corresponding EMSs. The psychometric properties of the short form of this instrument also appear to be on par with those of the full (205-item) scale, demonstrating similar levels of reliability, validity, and clinical utility [64, 65]. This scale has been validated in Iran, and the findings have indicated good reliability and validity for subscales among the Iranian population [66]. The scale showed appropriate reliability in the current study (α = 0.978; ω = 0.978). Table 1 presents the reliability estimates for each domain.

2.3.2. Barkley Deficits in Executive Functioning Scale (BDEFS)

The Barkley Deficits in Executive Functioning Scale was used to assess EFs. This questionnaire, which was developed by Barkley [67], assesses one’s degree of deficits in EFs on a 4-point Likert scale ranging from 1 (Never or rarely) to 4 (Very often). It comprises 89 items and is divided into five subscales measuring 5 EFs. Some examples of items are as follows: "I make decisions impulsively, I have trouble doing what I tell myself to do, and I remain emotional or upset longer than others". The total score is determined by summing all 89 items, ranging from 89 to 356, with higher scores reflecting lower EFs. This questionnaire has good validity and reliability [68, 69]. Its Persian version also shows good internal consistency and validity in Iranian individuals [70]. The questionnaire demonstrated good reliability in the present study (α = 0.988; ω = 0.988).

2.3.3. Young Internet Addiction Test (IAT)

IA was measured using the Young Internet Addiction Test developed by Kimberly Young [71]. The IAT is a self-reported measure consisting of 20 questions. Some examples of items are as follows: "How often do you find yourself saying “just a few more minutes” when online? How often do you check your email before something else that you need to do? How often do others in your life complain to you about the amount of time you spend online?". Items are rated on a 5-point Likert scale from 1 (Rarely) to 5 (Always). The total score is calculated by summing the scores of the 20 items, ranging from 20 to 100. Higher scores reflect a higher degree of IA. This scale has demonstrated good reliability and validity [72]. The Persian version of this questionnaire has been shown to have good psychometric properties among Iranian individuals [73]. The scale indicated adequate reliability in the present sample (α = 0.942; ω = 0.941).

2.4. Data analysis

We used IBM SPSS Statistics version 28 for statistical analyses and IBM AMOS version 24 for confirmatory factor analysis (CFA) and structural equation modeling (SEM).

Before testing the proposed conceptual model and hypotheses, a preliminary screening and assessment of the dataset were conducted to identify potential issues and to ensure the validity of the data, such as missing data, the presence of multivariate outliers, the normality of the variables, the linearity of the relationships, and the absence of multicollinearity. The Mahalanobis-squared distance was used to determine multivariate outliers [62]. Additionally, skewness and kurtosis values were employed to assess the normality of the variables [74]. Also, the linearity of the relationships through scatterplot analysis was assessed [75]. Furthermore, the absence of multicollinearity was checked by examining the variance inflation factor (VIF) [76]. Then, descriptive statistics and Pearson’s correlation analysis were examined.

SEM with the maximum likelihood estimation method based on CFA was employed to test the proposed conceptual model and hypotheses. First, CFA was utilized to test the validity and reliability requirements of the constructs within the model. Both McDonald’s omega (ω) coefficient [77] and Cronbach’s alpha (α) coefficient [78] were employed to evaluate the reliability of the constructs included in the model. Convergent validity was assessed by examining the average variance extracted (AVE) values [79]. The discriminant validity of the latent variables was tested using the Fornell-Larcker criterion [80] and the heterotrait-monotrait (HTMT) ratio [81]. Second, once a valid estimation of the constructs was confirmed, the structural model was tested using SEM. Third, the mediating role of EFs in the relationship between EMSs and IA was tested using a bootstrapping process with 5000 bootstrap samples and a 95% bias-corrected confidence interval (CI). CIs excluding zero indicated significant effects [82].

Given that the chi-square to degrees of freedom ratio (CMIN/DF) is sensitive to sample size, the following indices were used based on the mentioned acceptance thresholds to evaluate the model fit to the data. [83, 84]): goodness of fit index (GFI; ≥0.90), comparative fit index (CFI; ≥0.95 for excellent, ≥0.90 for good), Tucker-Lewis index (TLI; ≥0.95 for excellent, ≥0.90 for good), root mean square error of approximation (RMSEA; <0>

Results

3.1. Preliminary and Descriptive analyses

Preliminary screening and assessment of the dataset was conducted before the Statistical Analysis. Surveys with missing data and multivariate outliers were excluded from the final dataset. In Addition, the results indicated that all variables’ skewness and kurtosis values were between ±1, suggesting an approximate normal distribution [74] (see Table 1). Also, through scatterplot analysis, it was ensured that the relationships between the variables were linear. Furthermore, the results showed no VIF equal to 5 or larger, indicating a lack of multicollinearity in the variables [76]. Overall, all assumptions necessary for conducting SEM were satisfied.

The means and standard deviations of the measured variables are shown in Table 1. On average, participants in our study reported low to moderate levels in the domains of EMSs and low levels of deficits in EFs and IA. Also, Table 1 presents the bivariate Pearson’s correlations between variables included in the study. All of these correlations were statistically significant. All five domains of EMSs were positively correlated with IA and the highest correlation was observed between the Impaired Autonomy/ Performance domain and IA. Also, the results showed that IA and the domains of EMSs have a positive correlation with deficits in EFs, meaning that IA and the domains of EMSs are negatively correlated with EFs.

                                                          Table 1: Descriptive statistics, reliability, AVE, and correlation coefficients (n = 82)

Notes: D1 = Disconnection/ Rejection; D2 = Impaired Autonomy/ Performance; D3 = Impaired Limits; D4 = Other-Directedness; D5 = Over-Vigilance/ Inhibition; EFs = Deficits in EFs. M = Mean; SD = Standard deviation; Ske = Skewness; Kur = Kurtosis; α = Cronbach’s alpha reliability coefficient; ω = McDonald’s omega reliability coefficient; AVE = Average variance extracted. All square roots of the AVE values are shown in bold on the diagonal. **p ≤ .01.

3.2. Confirmatory factor analysis and reliability

This study employed a CFA to assess the measurement model’s fit and the reliability and validity of the research constructs. The results showed that the measurement model had an appropriate fit to the data (χ² (625) = 1735.683; CMIN/DF = 2.777; GFI = 0.916; CFI = 0.958; TLI = 0.953; RMSEA = 0.046; and SRMR = 0.065). These indices suggest that the model adequately represents the relationships between the observed and the latent variables.

Figure 2: Final results of conceptual model. Notes: Values are standardized coefficients. ***p ≤ .001; **p ≤ .01; *p ≤ .05; ns not significant.

The CFA analysis also confirmed the validity and reliability requirements for SEM. As shown in Table 1, all values ​​of Cronbach’s α and McDonald’s ω coefficients were above the suggested threshold of 0.70, 

indicating appropriate reliability for all constructs [85]. Also, Table 1 shows the AVE values exceeded the suggested cut-off value of 0.50, confirming acceptable convergent validity levels in the constructs [79]. All factor loadings were also statistically significant (p < 0.001) and items with factor loadings < 0>

consistently higher than its correlations with all other variables included in the model [80]. In addition, the HTMT ratios were below the cut-off value of 0.85 [81]. These results confirm discriminant validity.

3.3. Hypothesis testing

A structural model was estimated using the maximum likelihood method to evaluate the proposed conceptual model and hypotheses. The results are shown in Fig. 2. According to the results, the model presented an acceptable fit to the data (χ² (635) = 2033.604; CMIN/DF = 3.203; GFI = 0.909; CFI 

The results support both hypotheses. H1 hypothesized that EMSs (i.e. Disconnection/ Rejection, Impaired Autonomy/ Performance, Impaired Limits, Other-Directedness, and Over-Vigilance/ Inhibition domains) would predict IA. As shown in Fig. 2, the analyses determined that Disconnection/ Rejection, Impaired Autonomy/ Performance, Impaired Limits, and Other-Directedness domains predicted IA (β = 0.202; SE = 0.008; p < 0 xss=removed xss=removed xss=removed xss=removed xss=removed xss=removed xss=removed xss=removed>

Besides the direct links, the mediating effects were also tested. To determine whether EFs mediate the relationship between EMSs and IA, H2 was tested using a bootstrapping process with 5000 bootstrap samples and a 95% bias-corrected CI. The results of bootstrap analyses indicated that Disconnection/ Rejection, Impaired Autonomy/ Performance, and Impaired Limits domains were indirectly and positively associated with IA via EFs (See Table 2). Therefore, H2 was supported, providing evidence of the mediating role of EFs in the relationship between EMSs and IA.

                                                                             Table 2: Summary of mediation effect analysis (n = 826)

Notes: Bootstrap sample size = 5000; CI = Confidence interval; β = Standardized coefficient; SE = Standard error.These results indicated that Disconnection/ Rejection, Impaired Autonomy/ Performance, and Impaired Limits domains can, directly and indirectly, predict IA. While the Other-Directedness domain can only predict IA directly and the Over-Vigilance/ Inhibition domain is neither directly nor indirectly associated with IA.

Discussion

The present study examined the impact mechanism of EMSs on IA through EFs among Iranian university students by applying the I-PACE model. This section is structured based on the hypotheses analyzed in this study, and the limitations and conclusions of this study are presented at the end. Three important findings can be derived from the results. First, there was a significant relationship between the four domains of EMSs and IA. Second, the mediating role of EFs in the relationship between EMSs and IA was confirmed. Finally, the results supported the I-PACE model among Iranian university students. The findings of this study extend previous studies about the effect of EMSs on IA and explore the mediation mechanisms among these variables, which help understand the mechanism of IA more accurately and provide more effective guidance for IA intervention among university students. In the first part of this section, we discuss the main findings following the hypotheses proposed in this study. Next, we explain the limitations of the study.

4.1. Associations between EMSs and IA

The results of the present study showed that there is a significant positive relationship between schemas of the domains of Impaired Autonomy/ Performance, Impaired Limits, Disconnection/ Rejection, and Other-Directedness with IA. These findings are in line with the previous studies [39, 43, 44] and are consistent with the theory of Young et al. [26] and Ball [86] who have explained that EMSs underlie several psychopathologies. In fact, schemas are designed to help us survive in adverse environmental conditions [87], in other words, negative experiences in early childhood reinforce negative emotions and cause individuals to avoid their emotions when faced with similar situations. This avoidance in turn can lead to negative emotional states and maladaptive coping strategies [26]. Therefore, IA can be conceptualized as a maladaptive coping mode utilized for emotional regulation through which individuals cope with their negative thoughts and emotions. Furthermore, the existence of EMSs can lead to reduced cognitive flexibility [53, 54], which makes individuals unable to direct their attention to other ways away from themselves and their problems [88], which in turn may lead to an increase in Internet use, as the most accessible method, in facing problems. Previous studies have shown that the stronger the maladaptive schemas, the more likely addiction to substance use, Internet use, or obsessive behaviors [89]. Impaired Autonomy/ Performance domain schemas are associated with a low sense of personal agency which may lead to feelings of entrapment and hopelessness [26]. Therefore, Internet use becomes like a tool that a person uses to cope with their negative emotions, which are caused by a pattern of perceived personal flaws. Individuals with schemas of the Impaired Limits domain are vulnerable in regulating their emotions, managing their impulses, and engaging in goal-orientated behaviors [26]. As a result, despite the negative consequences across different contexts in their lives, they often engage in impulsive and behavioral addictions and tend to use the Internet as a quick solution to regulate their mood. Disconnection/ Rejection domain schemas, which are intrinsically associated with insecure attachment style and neglected core emotional needs such as love, support, and belonging [26], often lead to the development of several coping mechanisms to reduce psychological distress and emotional pain, including maladaptive self-soothing strategies such as problematic Internet use. Individuals with schemas of the Other-Directedness domain, who seek to gain others’ approval, are afraid of being abandoned, and their sense of self-worth depends on the response of others [26], may take any action to satisfy their needs (others’ approval, continuous emotional relationships, sense of value induced by others, etc.), and naturally, the Internet is one of the most accessible and easy solutions for these people.

4.2. EFs as mediators

The results demonstrated that EFs serve as a mediator between EMSs and IA. First, EMSs of the Impaired Autonomy/Performance, Impaired Limits, and Disconnection/Rejection domains predicted deficits in EFs significantly, which is in line with previous studies [52-55]. As previously mentioned, schemas are designed to help us survive in adverse environmental conditions [87], and when faced with new challenges, different types of them may be activated to effectively deal with the difficult situation and the resulting emotions [90].  A key component of EMSs includes emotions, and differences in the expression and regulation of emotions account for a large range of individual personality differences [91]. Individuals with high levels of EMSs in mentioned domains tend to believe that they are unworthy of love and connection, incapable of achieving success, and unable to control their lives [26]. This negative self-worth can lead to strong negative emotions [26, 92, 93] that interfere with EFs. This result can be interpreted using the dual competition model [94, 95], which attempts to explain the interaction between emotion and EFs in terms of shared processing resources. The model describes EFs as capacity-limited processes engaged in evaluating the behavioral relevance of stimuli and tasks in question. The behavioral interference of emotion often observed when high-arousal items are processed can be interpreted in terms of competition for finite available resources. According to the model, task performance is typically impaired in the presence of a task-irrelevant emotional stimulus because resources needed for the primary task are utilized, at least in part, toward the processing of the emotion-laden stimulus. Second, deficits in EFs were positively linked to IA, which is consistent with previous research [56-60]. EFs are control systems that allow us to regulate our behavior in a planned, goal-oriented, flexible, and effective manner [51, 96, 97]. Poor EFs are associated with deficits in goal setting, reduced self-control capacity, difficulty in shifting attention, etc. [98]. Control processes and EFs may significantly influence one’s cognition, especially coping style and expectations of Internet use. Therefore, deficits in EFs, especially in situations where a person is confronted with Internet-related cues, may lead to difficulties in developing other coping strategies than turning to the Internet to deal with negative mood [99]. As a result, the reduction of EFs leads to disadvantageous decision-making in the face of Internet-related cues. In this regard, Brand et al. [24] propose a dysfunctional interaction between poor executive control and situationally accelerated reward-seeking, which may promote disadvantageous decision-making to use certain Internet applications/sites to reduce craving and increase mood, that may increase the risk of IA in university students with deficits in EFs.

4.3. Implications for theory and practice

From a theoretical perspective, extending previous studies on the influence mechanism of EMSs on IA among university students, the present study provides empirical support for the I-PACE model of IA among university students in the context of Iranian culture as well as a reference for further research on the formation mechanism of IA. From a practical perspective, our findings may help guide the prevention and intervention of IA among university students. In general, further attention should be given to developing IA prevention and intervention programs. First, when screening and choosing a target population for further prevention and intervention programs, the population with schemas of domains of Impaired Autonomy/Performance, Impaired Limits, and Disconnection/Rejection and with deficits in EFs should be of particular concern. Second, and even more importantly, our results could offer invaluable knowledge on how to prevent and intervene in IA among university students. Specifically, schema therapy could have the potential to decrease IA in university students. Therefore, clinicians can apply the schema model with their clinical assessment to identify the EMSs that contribute to IA and to develop case conceptualization for treatment planning. In addition, the finding that EFs mediate the associations between EMSs and IA provides important implications for practice. Since EMSs are resistant to change [26, 45], to prevent and intervene in IA in university students, training techniques should be used to improve students’ EFs skills because this may be more efficient than directly altering EMSs.

4.4. Limitations and further directions

The present study had some limitations. First, as the results were obtained based on cross-sectional data, the structural relationships analyzed in this study should be interpreted with caution. Thus, future studies should use longitudinal data and clinical trials to better understand the structural relationships between Brain-Behavioral Systems, EFs, and IA. Second, all data were collected through self-report questionnaires, which may have increased bias. Future measures of peer nomination and behavioral tasks could be added, and data could be collected from multiple sources of information to make the data more realistic and reliable. Third, this study did not distinguish IA into specific subtypes. Previous research has shown that it is important to distinguish generalized IA from specific IA [100, 101]. Therefore, more information on Internet use needs to be included in future studies to verify whether the current findings are appropriate for generalized IA or specific IA. Fourth, the data were not obtained from a completely random sample, which did not lead to generalization. Finally, factors such as not considering gender differences, the study population, and temporal context might limit the generalizability and external validity of the findings of this study.

Conclusion

The present study extends the literature on EMSs and their impact on IA. In summary, this study explored the relationship between EMSs and IA among Iranian university students by using the I-PACE model. The results indicated that EMSs influence IA either directly or indirectly through EFs. Given that IA is not only harmful to the physical and mental health of university students but also places a large burden on their families and society, this study suggests that further attention should be given to developing IA prevention and intervention programs, especially in populations with schemas of domains of Impaired Autonomy/Performance, Impaired Limits, and Disconnection/Rejection and with deficits in EFs. Also, schema therapy and training techniques to improve EFs should be put on the agenda of clinicians and therapists.

Funding

This study did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Declaration of competing interest

The authors report there are no competing interests to declare.

References

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I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

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Baheci Selen

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

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Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

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Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

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Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

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Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

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Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

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S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

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Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

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Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

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Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

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Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

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Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

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Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

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Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

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Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

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Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

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Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

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Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

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Zhao Jia

Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."

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Thomas Urban

I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.

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Cristina Berriozabal

To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.

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Dr Tewodros Kassahun Tarekegn

"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".

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Dr Shweta Tiwari

I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.

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Dr Farooq Wandroo

Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.

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Dr Anyuta Ivanova

We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.

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Dr David Vinyes