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Research Article | DOI: https://doi.org/10.31579/2578-8965/268
Lecturer at the University of Duhok, College of Medicine, Specialist at Duhok OBGYN Teaching Hospital, Kurdistan Region, Duhok city, Iraq.
*Corresponding Author: Banav N Muhammed, Lecturer at the University of Duhok, College of Medicine, Specialist at Duhok OBGYN Teaching Hospital, Kurdistan Region, Duhok city, Iraq.
Citation: Banav N Muhammed, (2025), Maternal Outcomes in Women Complicated with sickle Cell Disease, J. Obstetrics Gynecology and Reproductive Sciences, 9(4) DOI:10.31579/2578-8965/268
Copyright: © 2025, Banav N Muhammed. This is an open-access article distributed under the terms of The Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 28 May 2025 | Accepted: 10 June 2025 | Published: 16 June 2025
Keywords: hemoglobinopathy; maternal outcomes; maternal morbidity; maternal mortality; sickle cell disease; vaso-occlusive crisis
Background: Sickle cell disease is an autosomal recessive hemoglobinopathy that is characterised by vaso-occlusive complications, and pregnant women with this condition are more likely to experience adverse consequences for both the mother and the fetus.
Objective: The study design is to evaluate the maternal outcomes in women with sickle cell disease.
Methods: This case-control study was carried out at the Duhok Obstetrics and Gynaecology Teaching Hospital in Iraqi Kurdistan between March 2020 and March 2025 .The 77 pregnant women in the study were divide d into two groups: the study group, also known as the SCD group, consisted of 30 pregnant women with SCD and was compared to the control group, also known as the non-SCD group, which consisted of 47 pregnant women without SCD who gave birth at the same time for study group .The inclusion criteria were ,Pregnant women who had been previously diagnosed with homozygous SCD (HbSS), the diagnosis was determined through hemoglobin electrophoresis or genetic testing which relied on documented physician notes .The individuals with sickle cell trait or other SCD genotypes , smoker and twin pregnancy were excluded.
Results: Over the course of the study, the mean maternal age in the SCD patients was 23.14 ± 4.21 years, compared to 22.11 ± 3.11 years in the control group (P=0.221). Twenty-seven SCD patients (90 %) were primigravid, compared to 38.29 percent of the women in the control group. The mean number of admissions was 2.02 ± 1.01 for the SCD group, compared to 1.01± 0.01for the non-SCD group. There was a statistically significant difference (p < 0.0001).Vaso-occlusive crises were responsible for 14 cases (46.6%) of hospitalisations in the sickle cell disease group. The study discovered the following about the mode of delivery: Ten patients (33.33%) in the SCD group had birth vaginally. Only one patient (3.33%) had an operational vaginal delivery (OVD), while eleven patients (36.66%) needed an emergency caesarean delivery (CD). Forty-four patients (93.61%) in the control group had vaginal births.
Conclusions: sickle cell disease is still a significant factor in pregnancy and delivery-associated problems. A planned pregnancy with early scheduled antenatal care would be essential to provide sufficient healthcare in a tertiary hospital,
Sickle cell disease (SCD) describes any of the syndromes in which the sickle mutation is co-inherited with a mutation at the other beta globin allele that decreases or eliminates normal beta globin production.
Obstetrical and fetal complications, as well as SCD-related medical complications, are more likely to occur in pregnancies due to metabolic needs, hypercoagulability, and vascular stasis morbidity and mortality can be considerably reduced by having access to a multidisciplinary care team that is educated on sickle cell disease and high-risk obstetrics [1,2].
The main characteristics of sickle cell disease (SCD) are haemolytic anaemia and vaso-occlusion, which can result in tissue ischaemia or infarction as well as acute and chronic discomfort. Early in life functional hyposplenism brought on by splenic infarction raises the risk of infection. Morbidity and mortality are significantly impacted by these consequences [3, 4].
Preconceptional evaluation and counselling should be carried out due to the risks of pregnancy for both the fetus and women with sickle cell disease (SCD). This includes testing the patient's partner for hemoglobinopathy to determine the type and risk of inherited disease in the offspring, followed by genetic counselling, stopping the use of medications that are contraindicated during pregnancy (such as hydroxyurea, iron chelation, angiotensin converting enzyme inhibitors, and angiotensin II receptor blockers), updating immunisations, and providing information on the course of SCD during pregnancy, the impact of SCD on pregnancy, and the outcome of the infant [4,5,6,7].
SCD can be identified either prenatally or preimplantation. Many assisted reproductive methods can help prevent an impacted pregnancy.During pregnancy, severe anaemia and painful or vaso-occlusive crises are more frequent. Opioids should be used to treat extreme pain, just like in nonpregnant women. More frequent screening for asymptomatic bacteriuria, ultrasound screening for foetal growth restriction, foetal assessment in the third trimester, checking ferritin levels, and only administering iron supplements or prenatal vitamins with iron if the patient is iron deficient are some of the changes made to prenatal care for women with sickle cell disease. The first prenatal visit should be used to evaluate alloimmunisation, typically repeat such testing at 24 to 28 weeks and again at the time of birth if the results are initially negative.Foetal and neonatal haemolytic disease risk should be assessed in women with alloantibodies and treated appropriately. In order to ensure that appropriate blood is available for transfusion, if necessary, the blood bank should also be informed [4,8,9,10,11].
To lower the risk of vaso-occlusion, it's critical keep warm, hydration and oxygen, and take precautions against infection. With the exception of nonsteroidal anti-inflammatory medicines (NSAIDs), which are often avoided after 30 weeks of gestation due to an increased risk of premature closure of the ductus arteriosus, the therapy of painful vaso-occlusive episodes is the same as that for women who are not pregnant.The cornerstone of treatment for both pregnant and non pregnant women is opioids. It is ecommend prophylactic transfusion therapy for SCD patients who are at high risk of complications. A multidisciplinary team should be involved in customising transfusion therapy. Transfusion is also beneficial for expectant mothers with acute SCD problems [4,11,12].
Vaginal delivery is not medically contraindicated in SCD patients. It is reasonable to wait for spontaneous labour if there are no risk for either the mother or the fetus. Only the standard obstetrical indications are used to induce labour and conduct caesarean delivery. It is recommend postpartum preventive anticoagulation for women with sickle cell disease (SCD) who have caesarean deliveries. Additionally, Low molecular weight heparin (LMWH)is given following vaginal birth [4,13,14].
The length of postpartum therapy following caesarean delivery is depend on the individual. Patients with a HbSS genotype, a history of moderate to severe sickle cell disease, advanced age, pulmonary disease, an indwelling central venous catheter, a high platelet count, a history of VTE, or other VTE risk factors are typically administered LMWH for six weeks. Pharmacologic thromboprophylaxis should be administered for five days following vaginal delivery; however, patients who stay in the hospital should continue taking anticoagulants. For women with sickle cell disease, hormonal contraceptives and the copper-releasing intrauterine device (IUD) are safe and efficient options. [4.15,16,17].
Between March 2020 and March 2025, this case-control study was carried out at the Duhok Obstetrics and Gynaecology Teaching Hospital in Iraqi Kurdistan. The Duhok Obstetrics and Genecology Teaching Hospital's Committee of Scientific Research Unit gave its approval to this work. All participants gave their informed consent. The 77 pregnant women in the study were divided into two groups: the study group, also known as the SCD group, consisted of 30 pregnant women with SCD and was compared to the control group, also known as the non-SCD group, which consisted of 47 pregnant women without SCD who gave birth at the same time for study group. The Duhok Obstetrics and Genecology Teaching Hospital, which offers specialised care to mothers referred from primary or secondary centers that are unable to offer such services, is where these mothers gave birth.
The inclusion criteria were, Pregnant women who had been previously diagnosed with homozygous SCD (HbSS), the diagnosis was determined through hemoglobin electrophoresis or genetic testing which relied on documented physician notes. The individuals with sickle cell trait or other SCD genotypes, smoker and twin pregnancy were excluded.
These patients' baseline characteristics, such as maternal age, parity, gestational age (GA) at delivery, and race, were all recoded following a thorough history, clinical examination, and investigations. For both groups, data was also collected on the mode of birth and antenatal complications. Baseline characteristics, antenatal complications and mode of delivery were compared between the two groups.
A software program current versions IBM (SPSS) Statistic, was used to statistically analyse the data. Quantitative variables were expressed as mean ± standard deviation while, descriptive statistics for nominal variables were expressed as numbers and percentages (%). The difference in the means of the quantitative variables was examined using the Student's t-test. To compare categorical data, the chi-square distribution test was employed. Results were interpreted as significant if the p-value was less than 0.05.
Over the course of the study, between March 2020 and March 2025, thirty pregnant women with homozygous SCD (HbSS) were compared to the control group, which included forty-seven pregnant women without SCD.
Maternal characteristics | SCD Group (n=30) | Non-SCD group (n=47) | P-Value |
| Maternal age (years) | 23.14 ± 4.21 | 22.11± 3.11 | 0.221 |
Parity Primigrav Multigravida |
27(90%) 3(10%) |
18(38.29%) 29(61,70%) | < 0.0001
|
Race White Non-White |
7(23,33%) 23(76.66%) |
31(65,95%) 16(34.04%) | < 0.0003
|
| GA at delivery (weeks) | 36.21±1.12 | 39.11±1.13 | < 0.0001 |
Table 1: Summarises the baseline characteristics of the mothers with SCD and the non-SCD groups.
Quantitative variables presented as mean ± SD, nominal variables as number (percent), P < 0.05 = Significant, P< 0.001 =highly significant, P > 0.05 = Not significant
The mean maternal age in the SCD patients was 23.14 ± 4.21 years, compared to 22.11 ± 3.11 years in the control group (P=0.221). The women in the two groups did not differ significantly in terms of maternal age.
Twenty-seven SCD patients (90 %) were primigravid, compared to 38.29 percent of the women in the control group.Ten percent of the SCD group and sixty-one percent of the control group were multigravida; P< 0.0001.The two groups' differences in parity were statistically highly significant.
In terms of race for both groups, the majority of SCD patients (76.66%) were not white, compared to (34.04%) of the control group, with a p-value less than 0.0001, this difference was statistically highly significant.
The SCD group's mean gestational age at delivery was 36.21± 1.12 weeks, whereas the other group's was 39.11± 1.13 weeks. With a p-value of less than 0.000, this difference was statistically highly significant.
| Antenatal complications | SCD Group (n=30) | Non-SCD group (n=47) | P-Value |
| Number of admissions | 2.02 ± 1.01 | 1.01± 0.01 | < 0.0001 |
| Vaso-occlusive crises | 14(46.6%) | 0(%) | |
| Anemia | 15(50 %) | 1(2.12 %) | 0.033 |
| UTI | 4(13.3 %) | 2(4.25%) | 0.150 |
| GDM | 2(6.6%) | 5(10.6%) | 0.553 |
| PE | 9(30%) | 3(6.38%) | 0.005 |
| blood transfusion | 11(38.6%) | 1(2.12 %) | 0.0001 |
| FGR | 9(30%) | 2(4.25%) | 0.001 |
| VTE | 0(%) | 0(%) | |
| PPH | 0(%) | 0(%) | |
| Maternal mortality | 0(%) | 0(%) | |
| IUFD | 0(%) | 0(%) | |
| Congenital anomalies | 0(%) | 0(%) |
Table 2: provides a summary of antenatal complications for the mothers with SCD and the non-SCD groups.
Quantitative variables presented as mean ± SD, nominal variables as number (percent), P < 0.05 = Significant, P < 0.001 =highly significant, P> 0.05 = Not significant
The mean number of admissions was 2.02 ± 1.01 for the SCD group, compared to 1.01± 0.01for the non-SCD group. There was a statistically significant difference (p< 0.0001).
Vaso-occlusive crises were responsible for 14 cases (46.6%) of hospitalisations in the sickle cell disease group. Only one case in the non-SCD group had anaemia, compared to 15 cases (50%) in the SCD group. There were statistically significant differences between the two groups.
Four cases (13.3%) of the SCD group had urinary tract infections (UTIs) that required hospitalisation, compared to two cases in the non-SCD group. The two groups' differences were not statistically significant.
Compared to 5 out of 47 patients (10.6%) in the control group, 2 out of 30 patients (6.6%) in the SCD group developed gestational diabetes. There was no statistically significant difference (p = 0.553).
Two cases (4.25%) in the non-SCD group and nine cases (30%) in the SCD group had pregnancies complicated by fetal growth restriction (FGR). There was a statistically significant difference. (p =0.001).
Nine cases (30%) had preeclampsia in SCD group, Only one case developed eclampsia. There were no cases of eclampsia in the non-SCD group, however three cases (6.38%) experienced preeclampsia. The two groups' differences were statistically significant (p =0.005).
There were no reports of maternal death, venous thrombo-embolism (VTE), postpartum haemorrhage (PPH), congenital abnormalities, or intrauterine foetal death (IUFD).
Mode of delivery | SCD Group (n=30) | Non-SCD group (n=47) | P-Value |
| Spontaneous vaginal delivery | 10(33.33%) | 44(93.61%) | < 0.0001 |
| IOL | 7(23.33%) | 1(2.12%) | 0.003 |
| Elective CD | 0(%) | 8(26.66%) | |
| Emergency CD | 11(36.66%) | 2(4.25 %) | 0.0002 |
| OVD | 1 (3.33%) | 1(2.12 %) | 0.746 |
Table 3: provides a summary of the mode of delivery for the mothers with SCD and the non-SCD groups.
Nominal variables as number (percent), P < 0.05 = Significant, P < 0.001 =highly significant, P > 0.05 = Not significant
The study discovered the following about the mode of delivery: Ten patients (33.33%) in the SCD group had birth vaginally. Only one patient (3.33%) had an operational vaginal delivery (OVD), while eleven patients (36.66%) needed an emergency caesarean delivery (CD). Forty-four patients (93.61%) in the control group had vaginal births. Eight patients (26.66%) underwent elective caesarean sections, whereas two patients (4.25%) needed an emergency caesarean section. OVD was performed on one patient (2.12%). Crucially, the statistical analysis revealed notable variations in the two groups' delivery methods.
Sickle cell disease during pregnancy are more likely to experience maternal morbidity and mortality. However, multidisciplinary care can result in positive outcomes for both the mother and the fetus [18,19,20,21].
According to our data, the majority of SCD patients were primigravida, as women with SCD have a long inter-pregnancy interval and low parity due to pregnancy complications associated with the disease but pregnancy rates did not differ, according to a prior study on reproductive issues in SCD in Brazil [22].
In our study the majority of SCD patients were non-white, which is consistent with a study that indicated the most of SCD patients were black [23]. The study's mean gestational age at delivery for SCD patients was ( 36.21±1.12), which is similar to the Koshy et al [24].
According to our findings, the SCD group experienced a considerably higher number of antenatal hospital hospitalisations than the non-SCD group. For the SCD group, anaemia and vaso-ooclusive crises were frequent reasons for hospitalisation. Vaso-ooclusive crises accounted for the majority of antenatal admissions, according to one study [25]. Anaemia was the most common cause, followed by sickle cell crises, according to a 10-year retrospective research [26].
Our investigation found that there was a significant difference in the incidence of preeclampsia between the two groups. This is in line with the results of many other investigations that found a significantly higher incidence of preeclampsia in women with sickle cell disease [27–29]. This contrasts with three previous studies conducted in Bahrain [30–32]. There is no conclusive evidence in the literature or published research linking gestational diabetes and sickle cell disease. Interestingly, our results revealed that the SCD group had a considerably lower incidence of gestational diabetes mellitus than the non-SCD group. Women had significantly higher rates of UTI during their pregnancy than controls.
While there was no significant difference in the prevalence of UTIs between mothers with SCD and controls in our investigation, a meta-analysis study conducted in Bahrain revealed a statistically significant elevated risk of UTIs in pregnant women with SCD [31,33].
Compared to the controls, the prevalence of blood transfusions was substantially greater among SCD women. The findings of a systematic review that demonstrated a statistically significant elevated risk of blood transfusions are in line with this [31].According to our research, we found increasing the risk of fetal growth restriction , utero-placental vascular stasis, a history of preeclampsia, and a history of severe anaemia all increase the likelihood of fetal growth restriction [34–35].In the SCD group, no congenital anomalies were seen, also SCD did not raise the risk of IUFD in our investigation; this could be because of timely delivery and antenatal fetal surveillance , which was similar to what was discovered in another study [31].
In our investigation, there was no maternal mortality among the SCD patients. There was no significant difference in maternal fatalities between the SCD and control groups, according to our study and the one study [31]. However, a number of additional investigations have discovered that SCD patients had a markedly higher maternal death rate [36,37].
Our findings showed a significant difference in the two groups' modes of delivery, including caesarean sections, which is in line with researches showing that individuals with sickle cell disease have a greater rate of caesarean deliveries [28,29,33]. In contrast, with one study's findings [31].
It should be noted that this study had three limitations. First, the sample size was too small. The second limitation of the study was that it was limited to short-term maternal outcomes during delivery. The third limitation, we were unable to study the impact of treatment on pregnancy outcomes. The study's main Strengths were that it was carried out at a tertiary center in Duhok city that the patient was delivered by a skilled obstetrician and where care was regularly and freely provided lastly it was able to choose a comparable group of pregnancies that were unaffected by SCD and matched on year of delivery.
sickle cell disease is still a significant factor in pregnancy and delivery-associated problems. A planned pregnancy with early scheduled antenatal care would be essential to provide sufficient healthcare in a tertiary hospital,it need a multidisciplinary team of skilled pediatricians, obstetricians, and hematologists to closely monitors these pregnancies.
'Not applicable'
The author would like to express gratitude to every member of the Duhok OBGYN Teaching Hospital, involved in the trial of this hard work including: operation team, laboratory staff, anesthetist's team, postgraduate students and everyone involved in the collection and interpretation of the data.
The datasets used and/or analysed during the current study available from the corresponding author on reasonable request
There was no source of funding for this research. All coasts were be covered by the author.
Contributions: Banav N Sulevanay (manuscript writing/editing, Data analysis, data collection collection., design of the study and revised the manuscript for intellectual content).
Ethics declarations
The ethical approval of the study protocol was received from the Duhok OBGYN Teaching Hospital Scientific Committee. In compliance with ethical guidelines, involving human populations, Informed Consent was obtained from all patients. All procedures were carried out in accordance with the Helsinki Declaration. patient confidentiality was safeguarded by anonymizing personal data. All required permissions were obtained from relevant institutional authorities before data collection.
The authors declare no competing interests.
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Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
