Influence of Feeding Baobab Seed Cake on Milk Production and Quality of Desert Goats

Research Article | DOI: https://doi.org/10.31579/2637-8914/312

Influence of Feeding Baobab Seed Cake on Milk Production and Quality of Desert Goats

  • I Bushara 1*
  • Dalia, A. M. Al Basheir 2

1 Department of Animal Production, Faculty of Natural Resources and Environmental Studies, University of Kordofan El-Obied, Sudan.
2 Faculty of Animal Production, University of East Kordofan, Sudan.

*Corresponding Author: Ibrahim Bushara, Department of Animal Production, Faculty of Natural Resources and Environmental Studies, University of Kordofan El-Obied, Sudan.

Citation: I Bushara and Dalia, A. M. Al Basheir, (2025), Influence of Feeding Baobab Seed Cake on Milk Production and Quality of Desert Goats, J. Nutrition and Food Processing, 8(6); DOI:10.31579/2637-8914/312

Copyright: © 2025, Ibrahim Bushara. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 15 April 2025 | Accepted: 22 April 2025 | Published: 30 April 2025

Keywords: desert goat; supplementation; baobab seed cake; milk production; Sudan

Abstract

The study was conducted in Al-Newala Village south ELObied town, Sheikan locality in North Kordofan state, Sudan. The milk production and composition of desert goats fed varying levels of baobab (Adansonia digitata) seed cake supplement was investigated over a period of 135 days. Twenty-four (24) adults pregnant does of Desert goats were randomly allotted to four dietary treatments with six animals per replicate in a completely randomized design to determine the quantity and quality of milk produced. The does were of similar initial body weight. They were randomly assigned to four supplementary feeding treatments. Group A was used as a control (un supplement as in farmer practice), the second group B was supplement with diet of 65% baobab seed cake, group C with diet of 55% baobab seed cake and group D was supplemented of 45% baobab seed cake. All does in all groups were subjected to natural grazing. The results indicated that supplementation with baobab seed cake had a highly significantly (P<0.05) effected milk production on 90 days, total milk production and daily milk yield. The does in group B had registered highest significantly (P<0.05) more milk (116.92 Lb) than those in group C and D as 114.15 Lb and 107.97 Lb respectively. The least milk was produced by the A group (control) of (79.73Lb) and which was significantly (P<0.05) less than supplemented groups. The daily milk production indicated that the does supplemented with baobab seed cake yielding significant (P<0.01) higher milk than control groups as 0.88,1.30, 1.27 and 1.20 Lb for group A, B, C and D respectively. The data indicated that supplementation had exerted a significant (P<0.05) effect on fat during 605-90 days with higher fat percentage in group C in 30-60 days as 3.75% and group D as 3. 57%. Protein % showed significant (P<0.05) effect during 0-30 and 60-90 days, where high percentages were in group C with 3.77%. Lactose and as content secured non-significant effected by baobab seed cake supplementation. In conclusion supplementation with baobab seed cake diet to Sudanese Desert goats during dry season improved milk production and inclusion of baobab seed cake at 65 % in the diet of Desert goats gave the highest milk yield.

Introduction

Goat production plays a very vital role in the livelihood of rural populations in Sudan as it contributes significantly to improvement of family nutrition and health. The Desert goat is indigenous goat breeds found in western Sudan. Records of its dairy performance in the natural environment it produces a low quantity of milk when compared with other goat breeds [1]. The nutritional role of milk and milk products in human diet is well documented [2]. Milk from ruminants is a good alternative to augment animal protein intake.  Increased awareness of the importance of milk in tropical areas has led to increased demand for milk and its products [3]. The rising demand for milk and its products in the tropics has made it imperative to find means for increasing local milk production, even outside their natural habitat/environment; this practice helps in performance evaluation of animals in locations outside their domain [4]. 

Milk quality and quantity is very dependent on the type of feed used in farming [5]. Generally, farmers in Sudan have minimal sources of feed for their domestic animals. Feeding system mainly depends on the use of forage, native grasses, legumes and field grass originating from the surrounding environment with limited sources and low nutritional quality (protein content) affect productivity.  Under such systems livestock production is constrained by scarcity and fluctuating quantity and quality of the year-round feed supply during the dry season [6 -7]. As a result, animals consume higher quantity of less palatable species and protein content, which consequently results in loss of body weight and low milk production. In order to maximize opportunities presented for milk production by goats, so it is significant to improve the quality of feed and explore new kind feed sources to increase the quality of milk. [8].

Promotion of concentrate feeding to improve low quality dry season feeds is limited by high competition with humans as well as soaring cost. It was reported that high competition for consumption of conventional protein sources between human beings and the livestock industry in the last two decades has resulted in an inadequate supply of dietary proteins [9]. Feeding of ruminant livestock generally becomes a challenge to farmers during dry season but due to their small herds the small scale farmers are the hardest hit given the high feed costs, especially energy and protein sources. So it is significant to improve the quality of feed and providing adequate good-quality feed and explore new kind feed sources to increase the quality of milk and maintain their productivity while mitigating climate change [8]. The problem of feed shortage can be addressed by the use of locally produced good quality alternative non- conventional feed materials which are nutritious and affordable [10].  Therefore, there is a need to exploit non-conventional protein sources. Research on low-cost and locally available indigenous protein sources is very important, especially those which do not attract competition with human beings and the ever-expanding intensive livestock production. The use of local indigenous multipurpose tree products and by-products, such as seed cakes and leaf meals is one such possible alternative. Utilization of non-conventional feedstuffs especially when it encourages a shift to other ingredients that are not edible to man but readily available will reduce the cost of feed and maximize the returns from small ruminant production [1].

Reports have indicated that one of the potential low-cost and locally available protein sources in small ruminant diets is Adansonia digitata (baobab) seed [11]. Baobabs trees are widespread all over the hot, drier regions of tropical Africa and are prevalent Sudan and are commonly considered as an African symbol [11-12]. Baobab seeds are rich in protein and contains substantial amount of energy [11]. Baobab seed cake (BSC) has a crude protein content of about 17% [13], which is inadequate for it to be used as a sole protein source in mid-lactating dairy cows. The supplementation of animal rations with a protein source is necessary to meet the protein and amino acid requirements of the animal for a better performance. Many studies have evaluated the effect of Baobab seed cake (BSC) on cows and ewes. To our knowledge, there are few published studies on the effects of Baobab seed cake (BSC) in the lactating goat. However, there is limited information about the feeding value of Adansonia digitata seedcake as feed for goats in Sudan. Furthermore, no studies have investigated the effect of the incorporation of Baobab seed cake (BSC) and ground nut cake mixture in the goats’ diet. In this study aims to evaluate the effects of diets supplemented with Baobab seed cake (BSC) on desert goat milk production performance and quality in North Kordofan state, Sudan.

Materials and Methods

The experiment was conducted in Al-Newala Village (Longitudes 30.34˚-30.05˚ N, Latitudes 12.93˚-13.34˚E), about 35 km south ELObied town, Sheikan locality in North Kordofan state. Average temperature varies between 30-35oC during most of the year with peaks of above 40oC during April, May and June. The rainy season extends from July to October with maximum rainfall in August. Long-term averages annual rainfall is about 280 mm.

Experimental design and duration 

The study involved three experimental groups and one control group, which made a total of four treatments. A completely randomized design was used for the experiment, with six replicates of pregnant doe's of Desert goats per treatment. animals were randomly distributed to 4 treatments. The experiment lasted for 135 days (7 days pre-experimental period, 45 days for last months of gestation period, and 90 days after kidding).

Experimental animals and feeding management

The study was carried out on Twenty four (24) adult pregnant doe's of Desert goats were used from the last month of pregnancy until 90 day of lactation. The goats were collected from small-scale farmers from in Al Newala Village. The does were of different in age with a range of >1 year to three years of age. The target goats were ear tagged, weighed and randomly divided into four groups A, B, C and D each group component of (6) does according body weight.  All groups were treated against endo-and ecto-parasites, and vaccinated against food and mouth disease, Anthrax and Hemorrhagic Septicemia. All goats were housed in partially shaded pens, constructed from local materials of woods and were equipped with clean water troughs. 

All goats depending on pasture to maintained their roughage and they were daily turned to grazing from 8.00A.m to 6.00p.m. These goats were fed experimental diets containing different levels of baobab seed cake in a formulated diet (Table 1). Group A were used as control with, and managed according to the prevailing traditional system which relies mainly on grazing with no supplementation. Group B, beside allowed to grazing similar to the control group were managed with ration 1. Group C, managed with grazing and supplementing with ration 2, last group D were managed with grazing and supplement with ration 3. Supplementation of groups B, C and D were performed during night after grazing time by rate of 200gm/head/day. Animals were hand milked twice daily.

Milk production

Collection of milk from each lactating doe commenced 7 days after parturition to allow for colostrums intake by the kids. Milking was done by hand twice daily at 7am and 5pm in the presence of the kids for 90 days. Milk let-down was stimulated by the suckling the kid for 5 minutes after which the doe was milked. The milk was weighed using a precision scale (with a sensitivity of 0.1 g). Weight of the kids was taken before and immediately after suckling to estimate milk intake. Kids were separated from does after milking. Milk yield was calculated as the summation of milk off-take and intake by the kid

Milk Composition 

Fresh milk samples were taken every 15 days interval for chemical analysis for 60 days. The Milk samples (20 ml) from each does in all group were collected in sterile containers and kept in a refrigerator adjusted at 5 C0 pending the analysis for chemical composition. The analysis has been done according to methods of [14]; the crude protein was determined by the Kjeldahl method as described by [14]. Crude fiber determination was carried out using trichloroacetic acid (TCA) method. Fat content of milk was analyzed by Gerber method as described by [15]. Ash was determined according to [14]. Lactose and solids, not fat contents, were determined by difference. Analysis was done in the laboratory of Animal Production of ELObied agricultural Research Station, North Kordofan state, Sudan.

Chemical composition of supplementation rations and feeds 

Proximate composition of the ingredients used in concentrated ration formulation, supplemented diets (ration 1, 2 and 3) and some grasses in wet and dry season samples were analyzed following standard procedures, according to Association of the Official Analytical Chemists, [16] (Table.1 and 2).

Components (%)Ration 1 (group B)Ration2 (group C)Ration 3 (group D)
Sorghum grains555
Baobab seed cake 655545
Groundnut Cake203040
Wheat Bran 999
lick salt0.250.250.25
Common salt0.750.750.75
Chemical composition of the experimental feed stuffs
DM%96.4096.4096.30
CP %30.5728.2026.30
CF%31.4828.4523.64
EE %6.206.005.07
NFE %48.2825.6835.66
Ash%5.305.045.00
 

Table 1: Ingredients of the experimental feed stuffs.

Plant speciesDMICPCFEENEFAshME(Mj/Kg
Cenchrus biflorus88.93.373.72911.311.15.93
Eragrostis termula93.32.980.50.89.006.85.95
Schoenefeldia gracilis93.32.279.20.811.16.76.03
Cenchrus setigrus96.34.780.81.09.83.76.29

Table 2: Chemical analysis of some grasses in dry season in the study area.

Statistical analysis:

The experimental design adopted for this study was the completely randomized design. All data collected were subjected to analysis of variance procedure using the General Linear Model (GLM) applicable to the experimental design and significant means were separated by Duncan’s multiple range tests, following the procedures of SPSS [17].

Results

Effect of supplementation of baobab seed cake on milk yield

The weekly milk yield of the goats for the 12 weeks of lactation is in (Table 3). Supplementation of baobab seed cake had significantly (P less than 0.05) more milk (116.92 Lb) (51.96 Kg) than those in group C and D as 114.15(50.73Kg) and107.07 Lb (47.59Kg) respectively. The least milk production was produced by group A of 79.73 Lb (35.44 Kg) and which was significantly (P less than 0.05) less than that produced by supplemented groups with baobab seed cake. 

Also, daily milk production was highly significant (P less than 0.05) affected by baobab seed cake where group B which with 65 percentage baobab seed cake had better milk production with 1.30 Lb (35.44 Kg). The daily milk production indicated that the does supplemented with baobab seed cake yielding significantly (P less than 0.01) higher milk than control groups.

The weekly milk yield of the desert goats for the 12 weeks of lactation is shown in (Figure 1). Milk yield increased steadily from the first week of lactation to the sixth week, then dropped for C, D and A groups, whereas sharp declined was noticed in group A. The supplemented groups showed better milk curve with long persistency yielding. The peak for the weekly milk yield was recorded at the 6th week of lactation for all the treatments except for the control (A).

Table 3: Effect of supplementation on milk production/Lb.

Figure 1: Effect of baobab seed cake on lactation curve of desert goats.

Effect of supplementation with baobab seed cake on milk composition

The effect of supplementation on milk chemical composition of experimental desert goats is illustrated in (Table 4). The data indicated that supplementation had exerted a significant (P less than 0.05) effect on fat and protein percentage during 60-90 days. Higher fat percentage during all period of 90 days was noticed in group C in 30-60 days as 3.75% and group D as 3.57%. Protein% showed significant (P less than 0.05) effect during 0-30 and 60-90 days, where high percentages were in group C with 3.77%.  Lactose and as content secured non-significant affected by baobab seed cake supplementation. Beside this, supplemented groups showed higher lactose and lower ash content compared with control group.

  FatCrude Protein
Animal GroupsNo.0-3030-6060-900-3030-6060-90
A63.303.623.18b3.40ab3.483.43b
B63.303.503.48ab3.45ab3.553.60ab
C63.383.753.22ab3.23b3.773.62ab
D63.123.523.57a3.65a3.603.75a
Overall means+SE243.28± 0.173.60±0.103.36±0.13*3.44±0.11*3.60±0.093.60±0.1*
abc  Values in same column with different superscripts differ at P less than 0.05

Table 4: Effect of supplementation on milk composition%.

Discussion

Milk production and composition are more depending on composition of the diet fed to animal, the energy balance and energy reserved of the animal. The average total milk production for Desert goats in this study was 104.69±3.36 Lb (46.53 Kg), with daily milk of 1.16±0.04 Lb (0.52 Kg) in a lactation period of 90 days, this level of production was comparable with that reported by [18]for Taggar goats, and lower than that reported by [1-4-8] and higher than that reported by [5]for West African Dwarf Goats Offered Moringa oleifera Herbage Supplement.

The present study indicated that there were highly significant differences in milk yield and daily milk yield between goats of different nutritional supplements with Baobab seed cake during early lactation. Milk yield was highest when baobab was fed at 65 % inclusion in the diet and least when no baobab (control) was fed. Although milk yield of goats fed baobab at 55% or 45 % inclusion was significantly different from each other, it was higher than that of control animals. Milk yield of goats in this study increased with addition of baobab to the diet and was directly proportional to protein intake by the supplemented animals compared to control group. This online with findings of [3-8-19]. Also [5] showed that nutrition improvement with multipurpose trees could be a means of increasing milk yield. Okunlola and Olorunnisomo [3] that the milk yield was significantly affected (P less than 0.05) with supplementation of Baobab seed cake. The supplementation that offered during third period of gestation had positive effect on sustain milk production since around 70% of fetal growth and most of glandular development and mammary tissue occur in this period. For this reason, a strategic supplement of high protein and energy quality should be offered, this fact agreed with [20-21] who reported that good nutrition is a prerequisite high milk yield and a successful rearing system. On the other hand, undernourishment in gestation and lactation in goats can have negative effects on milk yield [22]. Luana et al. [23] concluded that the diet nutritive value and nutritional planes during gestation affect tissue mobilization for support of milk production in early lactation. Generally, the nutritional plane and dietary composition during breeding and gestation (3 to 4 week before parturition) may affect milk yield and reproductive performances which on lines with [24]. Because it may also influence the ruminal microbiome and ruminal fermentation, which subsequently could impact milk production when switched to lactation diets. It was hypothesized that different nutritional planes during gestation may influence Lactational performance and energy utilization in lactating goats fed different lactation diets.

Contrary to the current results [25] found inclusion of Baobab seed cake in the diets of lactating cows reduces milk yield. Also, this result disagrees with the earlier reports of similar work on goats, [23-26] they found that the result from different supplementation showed no significant effect (P> 0.05) of milk production. The dietary concentrate level and nature of specific concentrate and forage feedstuffs impact level of milk production and characteristics of milk [23]. Does on framer's practice (control group) had lower milk yield compared with fed groups, this may be due to less nutrient requirements to meet mammary growth and milk production. Does on control flock began to mobilize their reserve more than does on fed group with baobo seed cake. This significant positive response in milk production observed in does supplemented due to sufficient energy intake by those females that allow for improved production, this agrees with the findings of [27] who reported that supplementing goat ration will increase milk production. This reinforces the argument for the good adaptive response of Desert local goats to erratic feeding conditions. Evidence has been found that under grazing conditions in difficult areas goats adjust their diet selection according to their nutritional needs, especially when the cost of gestation increases the demand for nutrients. The different in milk yield could be due the composition of the diet, type of livestock, and study area was responsible for the variations with the finding in this study, or may be attributed to feed intake and varying inclusion levels of baobab seed cake in the experimental diets.

The lactation curve characteristics of Desert goats showed that the milk production increased for all treatments during early lactation and reached its peak at the 6th week of lactation to reach mid lactation and then subsequently decreased until the 90th day of lactation. Daily milk yield showed significant decrease with advancing lactation, whereas, persistency of milk yield continued three weeks. This appears to be a genetic trait and may not be easily influenced by nutrition as reported by [28], where peak yield tended towards early lactation for local goats. The trend of lactation curve of Desert does in this study is similar to the report of [1-5], this was within the 2 to 5 weeks peak yield reported for Red Sokoto goats by [29] and comparable to 30 days reported for Saanen goats by Souza et al. [30], and not agreed with [4-28] who reported peak yield of milk occurred around 4th week of lactation during the 12-week. The increase in milk production is in line with the combination of several protein feed ingredients in the ration of donations from baobab seed cake and groundnut cake to maintain cells in the mammary gland and the production of hormones and enzymes that play a role in milk biosynthesis. The inclusion levels did not markedly affect yield in the Desert goats used because protein or energy supplements are usually more effective in enhancing milk yield in high genetic dairy goats such as Damascus than they do in low genetic non-dairy or non-selected breeds such as Desert goat. The Desert goat used in this study has not been selected and developed for dairy production.

In this study the values observed for milk components are within the normal range for the goat species, so the composition of the milk (fat and protein) was largely affected by the dry matter intake of the animals of baobab seed cake in the diet, this attributed to the impact of baobab seed cake on ruminal fermentation through enhancing small chain fatty acids and microbial nitrogen production. Similar results recorded by [3-4-8-19-26-31] that the quality of milk produced from these goats fluctuates according to the type of feed given. Also, Póti et al. [32] reported that different feeding strategies have different impact on the chemical composition of goat milk. Contrary to these results [20-33] stated that the composition of milk was not affected by the distributed diet. The absence of diet effects on milk chemical composition could be due to the lack of effects of long-chain unsaturated fatty acids of diets on ruminal bacterial activity [33]. The alternative feed resources are known for their high content in fiber and secondary compounds as phenols and tannins that could affect milk yield and quality by influencing chemical composition and fatty acid precursors in rumen and blood, which agreed with [33].

Fat content varied from 3.28 to 3.60 %, and significantly (P less than 0.05) milk fat yield, and he concluded these improvements followed Moringa oleifera inclusion might due to the high digestibility of dry matter intake, crude protein and crude fiber. Arief et al. [8] reported that enzymes help in the process of milk fat synthesis, where enzymes are proteins. An increased protecting protein supplement increases the number of enzymes to improve the process of milk fat synthesis. In the present study, however, milk fat content is lower at early lactation than at later stages probably because of declining milk yield which made the fat content more concentrated. This type of trend is characteristic of low yielding goats or non-dairy goats [34] or non-selected breeds of animals whose peak yield is usually the initial yield at the beginning of lactation which agreed with [23], where milk fat content decreased with advancing lactation. During early lactation, milk fat content is high not only because nutrients are partitioned towards mammary gland for milk production, but also because transfer of triacyglycerols to milk is more efficient at the beginning of lactation than at later stages. The significant of fat content in this study were not in line with many authors [20-23-35] they stated that milk fat content did not differ between supplemented groups.

The protein content in this study varied from 3.44 to 3.60 %. The protein and fat content of the milk increased with higher levels of baobab seed cake in the diet. This was influenced by the higher protein intake of goats as the level of baobab fruit increased in the diet, the range of protein reported her with in line with [3-4-19-36]. The milk protein content is a trait that changes during lactation and tends to behave inversely to milk yield, reaching minimum values in the second month of lactation, which coincides with the period of maximum milk production. The protein value across treatment contradicts report of [8-23] the result showed that the supplementation treatments did not significantly affect milk protein (P>0.05). Also [34-37] who reported that goats milk protein content was not markedly changed in responses to dietary energy (as fat) supplementation.

Milk lactose almost followed the trend of protein. The Lactose content in this study varied from 4.44 to 4.33 % and there were no significant differences in lactose content of the milk in goats fed different levels of baobab in the diet which on harmony with [3-8] who reported that it has been noted that lactose concentration in milk is not easily altered by nutrition. These results were not in line with the work of [19-35-37] who observed that addition of energy (as sunflower seeds) to goat's ration showed significantly higher lactose content through suckling and lactation. The levels of lactose in supplemented groups are the same as control, this is caused by the protein content of feed in the treatments are still able to meet the needs of the goat and the same as the control treatment. Feed protein will be remodeled into amino acids that are absorbed in the intestine to be converted into glucose in the liver through the process of gluconeogenesis, thereby increasing glucose levels in the blood and then increasing milk lactose levels. Ash content also varied from 0.77 -0.78%. Also, ash wan not affected by feeding baobab seed cake. These results were confirmed by [4-37] that ash values were not influenced (P>0.05) by graded level of baobab pulp and seed in the experimental diets. Disagreed with this El Otmani et al. [333] found that supplementation had significant effect on ash content. Baobab seed cake can be affordable to smallholder farmers who have access to it. Thus, baobab seed cake is a promising non-conventional protein source that has the potential to limit costs of livestock production to all farmers in the tropical region where it is found. However, there is need for sustainable harvesting of baobab to avoid negatively impacting on the environment or upsetting ecosystems especially wild animals which feed on the fruits.

Conclusion

Addition of baobab seed cake to the diet of desert goats increased milk yield of the lactating goats. Protein and fat content of goat milk increased while ash and lactose content were not altered with addition of baobab seed cake to the diet. Baobab seed cake enhanced milk production in desert goats.

References

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"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

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Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

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Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

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Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

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Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

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Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

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S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

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Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

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Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

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Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

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Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

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Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

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Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

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Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

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Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

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Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

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Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

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Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

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Zhao Jia

Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."

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Thomas Urban

I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.

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Cristina Berriozabal

To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.

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Dr Tewodros Kassahun Tarekegn

"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".

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Dr Shweta Tiwari

I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.

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Dr Farooq Wandroo

Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.

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Dr Anyuta Ivanova

We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.

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Dr David Vinyes

My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.

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Gertraud Teuchert-Noodt

To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina

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Dr Elvira Farina

Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.

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Dr Oleg Golyanovski

Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.

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Dr Susan Anne Smith

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.

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Dr Farahnaz Fallahian

Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.

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Dr Victor Olagundoye

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.

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Dr Susan Anne Smith

Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD

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Dr Eric S Nussbaum

Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.

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Hala Al Shaikh

Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.

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Dr Rakhi Mishra

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.

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Dr Walter F Riesen

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.

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Dr Jelle Lettinga

Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora

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Dariusz Ziora

Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.

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Dr Ravi Shrivastava

Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.

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Dr Aline Tollet

Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.

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Dr Chiara Giuseppina Beccaluva

Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti

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Dr Claudio Ligresti

Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.

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Dr Matteo Bonori

I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.

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Edouard Kujawski