AUCTORES
Globalize your Research
Research Article | DOI: https://doi.org/10.31579/2637-8914/292
Department of Animal Biochemistry and Nutrition, Sumitra Research Institute, Gujarat, India.
*Corresponding Author: Alagbe John Olujimi, Department of Animal Nutrition and Biochemistry, Sumitra Research Institute, Gujarat, India.
Citation: Alagbe J. Olujimi, (2025), Effect of Heliotropium Indicum Leaf Powder Supplemented Diets on growth Performance and Carcass Characteristics of Weaned Pigs, J. Nutrition and Food Processing, 8(3); DOI:10.31579/2637-8914/292
Copyright: © 2025, Alagbe John Olujimi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 17 January 2025 | Accepted: 17 February 2025 | Published: 03 March 2025
Keywords: Antibiotics; growth; heliotropium indicum; phytocomponents; performance
A 60 day experiment was carried out at Sumitra Research Institute, Gujarat, India to examine the effect of Heliotropium indicum leaf powder supplemented diets on growth performance and carcass characteristics of weaned pigs. A total of 50 crossbred male pigs (Landrace × Duroc) with initial body weight of 9.06 ± 0.44 kg weaned at 30 days of age were randomly divided into five treatments with six replicates (1 pig per replicate) and fed three experimental diets. Treatment 1; corn-soybeal mean (regular diet) without Heliotropium indicum leaf powder (control), treatment 2: regular diet with 0.50 g neomycin/kg diet while treatment 3, 4 and 5 received regular diet supplemented with Heliotropium indicum leaf powder at 100 g, 200g and 300 g per kg diet. A completely design was adopted and animals had unrestricted access to clean water and feed. Experimental results revealed that average daily body weight and average daily feed consumption varied from 0.14 to 0.26 kg and 0.71 to 0.82 kg respectively were higher among pigs in treatment 3, 4 and 5, intermediate in treatment 2 and lower in treatment 1 (p˂0.05). Increasing the dietary supplementation of Heliotropium indicum leaf powder decreased the feed to gain ratio from 5.25 to 3.15 (p˂0.05). Dressing percentage and weights of hind limbs, fore limbs, head, back, belly, heart, lungs and kidney were significantly (p˂0.05) influenced except for the spleen (p˃0.05). It was concluded that supplementing Heliotropium indicum leaf powder up to 300 g/kg in the diet of weaned pigs influenced their growth and pose no negative effect on the health status of animals.
Global concern over potential antibiotic resistance risks related to human health has driven interest in pig nutrition over the adoption of antibiotic free feeding systems (Caroline, 2022). Despite these debates on the role of antibiotics use in conferring antimicrobial resistance to human pathogens, many countries in Europe have issued a ban on the approval for antibiotics as growth promoters since January 2006 on precautionary grounds (Woodward, 2005; Jenny, 2022). Currently, there is an increasing interest to find alternative substances and strategies to improve the health status of farm animals for human consumption and the use of medicinal plant is considered as one of the potential alternative with no withdrawal period, no drug resistance, no environmental pollution and no toxic residue in final products (Jenny, 2021; Alagbe, 2024).
Heliotropium indicum is one of the underutilized perennial medicinal plant belonging to the family Boraginaceae and order Boraginales consisting of over 200 species distributed globally (Roy, 2015; Owolabi et al., 2015). The plant is found in many countries including, India, Pakistan, Bangladesh, Philippines, Nigeria, Kenya, Zambia, South Africa amongst others (Boye et al., 2012; Kumar et al., 2012). Heliotropium indicum can reach up to about 50 cm in height and its leaves are opposite or sub-opposite, alternate or sub-alternate and straight forward, sheet-shaped from ovate to elliptical, hairy, and sharp and 5 to 10 cm long in length (Pianowski et al., 2011; Kumar et al., 2014).In traditional system of medicine, the aqueous leaf extract and stem bark of Heliotropium indicum are used for the treatment of fever, stomach ache, arthritis, malaria, diarrhea, snake bite, kidney disease, sexually transmitted disease, urinary disease, cough, asthma, high blood pressure, epilepsy, convulsion, dysentery, cancer and general body pain (Ghosh et al., 2018; Suroowan et al., 2019).
Several phytochemicals or bioactive compounds have been identified in the plant including, tannins, triterpenoids, alkaloids, (example: heleurine N-oxide, cynoglossine, retronecine, helindicine and indicine, indicinine), saponins, steroids, flavonoids, triterpenoids, volatile oils amongst others (Odugbemi et al., 2007). The presence of these compounds makes the plant act as antimicrobial, antioxidant (Dash and Murthy, 2011), anti-inflammatory, cytotoxic (Veda et al., 2016), antibacterial, anti-helminthic, anticancer (Reddy, 2002), anti-diabetic, immune stimulator (Boye et al., 2012), digestive stimulator, antinociceptive (Chunthorng- Orn et al., 2016), analgesic, anti-hyperglycemic, anti-cataract (Abdel-Sattar et al., 2009), anti-plasmodial, antitussive (Odugbemi et al., 2007), antitumor, anti-allergic (Boye et al., 2012), larvicidal and pesticidal properties.
Previous studies have shown that supplementation of herbs or medicinal plants in the diet of animals could enhance the activities of endogenous enzymes in the gastrointestinal tract, thereby promoting absorption of nutrients and efficiency of feed utilization (Shittu et al., 20024). However, outcome from most of these studies have not been consistent, these discrepancies could be influenced by several factors such as, levels of supplementation (Daniel et al., 2023), processing method (Musa et al., 2020), composition of phyto-components amongst others. For instance, a study carried out by Alagbe et al. (2024), revealed that dietary supplementation of Heliotropium indicum leaf powder up to 80 g/kg in the diet of weaned pigs did not influence their growth performance. There is need to establish an optimum level and also provide scientific basis for the use of Heliotropium indicum leaf powder in animals feed. This research will not only address the increasing rate of antimicrobial resistance, it will also promote food safety and environmental sustainability.
Therefore, this study was designed to evaluate the effect of Heliotropium indicum leaf powder supplemented diets on growth performance and carcass characteristics of weaned pigs.
Experimental location, duration, collection and preparation of Heliotropium indicum leaf powder
Sumitra Research Institute’s Piggery unit in Gujarat, India was used for the experiment and animals were cared for following the guidelines and management procedures approved by Animal Production department of Sumitra Research Institute, Gujarat. The whole experimental period is eight weeks.
Heliotropium indicum leaves were collected within the premises of Sumitra Research Institute, Gujarat, India before it was sent to the institute’s taxonomy department for proper identification and a registration number GH/008/2023 was assigned after authentication. Collected leaves were shade dried for 13 days until the leaves turns pale brown and a constant weight was achieved before it was grounded into powder using an electric blender. The powdered leaf was collected into a labeled air tight plastic bucket before it was taken to the laboratory for further evaluation.
Management of experimental animals, diet and design
A total of 50 crossbred male pigs (Landrace × Duroc) with initial body weight of 9.06 ± 0.44 kg weaned at 30 days of age were randomly divided into five treatments with six replicates (1 pig per replicate) and fed three experimental diets. The feed used for this experiment was corn-soy bean meal based diet which was consistent with the National Research Council’s requirement for growing pigs (NRC, 2012) as presented in Table 1. Treatment 1; corn-soybeal mean (regular diet) without Heliotropium indicum leaf powder (control), treatment 2: regular diet with 0.50 g neomycin/kg diet while treatment 3, 4 and 5 received regular diet supplemented with Heliotropium indicum leaf powder at 100 g, 200g and 300 g per kg diet. The dietary treatment began on day eight after one week adjustment period and pigs were fed thrice daily (6:30, 12:00 and 15:00 H). They also had unrestricted access to clean fresh water and a completely randomized design model was adopted. Average initial body weight was taken immediately upon the arrival of pigs using a digital scale and thereafter on a weekly basis. Average body weight gain, daily weight gain, average total feed consumption and daily feed consumption were all calculated. Average body weight gain (expressed in kg) = Average final body weight minus average initial body weight.
Daily weight gain (in kg) = Average final body weight minus average initial body weight divided by the experimental period in days.
Total feed consumption = Left over minus feed served (expressed in kg)
Daily feed consumption (kg) = Left over minus feed served divided by the experimental period in days
Ingredients | Inclusion (%) |
Maize | 50.00 |
Rice bran | 5.50 |
Soy bean meal | 33.00 |
Oyster shell | 3.00 |
Bone meal | 6.00 |
HL-Lysine | 0.25 |
DL-Methionine | 0.25 |
*Growers premix® | 0.25 |
TNRoxin binder® | 0.02 |
Sodium chloride | 0.30 |
Total | 100.0 |
Determined analysis (expressed in %) | |
Crude protein | 23.18 |
Crude fibre | 5.05 |
Ether extract | 3.98 |
Ash | 3.62 |
Metabolizable energy (Kcal/kg) | 2800.6 |
Table 1: Composition and nutrient levels of experimental diets
Carcass characteristics evaluation
At the end of the experiment five pigs were selected per treatment and their average body weight was measured. Pigs were feed starved for 12 hours and given access to water before they were stunned, bled and their hair was removed after using sharp kitchen knife, eviscerated and cut into different parts. Weights of head, belly, fore limb, hind limb, back and those of organs (heart, lungs, kidney and spleen) were measured. Dressing percentage was estimated using the following formula:
Dressing % = Carcass weight divided by Live weight multiplied by 100
Phytocomponents in Heliotropium indicum leaf powder
Portable GriffinTM G510 gas chromatograph mass spectrometer was used to evaluate the various phytocomponents in Heliotropium indicum leaf powder. Quantification of various compounds was carried out at different optical densities. For tannins, saponins, alkaloids, flavonoids, steroids, glycosides, triterpenoids and anthraquinones at 310 nm, 450 nm, 280 nm, 520 nm, 660 nm, 360 nm, 570 nm and 640 nm respectively.
Proximate determination of experimental diet
Determination of proximate components was carried out using Perkin Elmer benchtop near infra-red analyzer (Netherlands). Kit was adjusted at an optical bandwidth, spectral resolution, wavelength range, and wavelength precision of 10.44 nm, 0.5 nm/data point, 1700 nm and 0.5 nm respectively according to the manufacturers’ recommendation.
Data obtained on growth performance and carcass characteristics was subjected to one -way analysis of variance using Statistical Package for Social Sciences (version 25). Significant differences among the treatments were subjected to comparisons using the Duncan multiple range test of the same software. All differences were considered to be statistically significant when p < 0>
Experimental Results
Composition and nutrient levels of experimental diets is presented in Table 1. The diet contains crude protein (23.18 %), crude fibre (5.05 %), ether extract (3.98 %), ash (3.62 %) and energy (2800.6 Kcal/kg).
As presented in Table 2, phytocomponents in Heliotropium indicum leaf powder. Result revealed the presence of flavonoids (609.7 mg/g), triterpenoids (258.9 mg/g), tannins (196.7 mg/g), alkaloids (102.6 mg/g), steroids (90.50 mg/g), saponins (85.31 mg/g), anthraquinones (30.65 mg/g) and glycosides (25.11 mg/g) in their order of abundance.
Phytocomponents | Composition (expressed in mg/g) |
Tannins | 196.7 |
Alkaloids | 102.6 |
Saponins | 85.31 |
Flavonoids | 609.7 |
Steroids | 90.50 |
Glycosides | 25.11 |
Anthraquinones | 30.65 |
Triterpenods | 258.9 |
Table 2: Phytocomponents in Heliotropium indicum leaf powder
As displayed in Table 3, growth performance of weaned rabbits fed with Heliotropium indicum leaf powder. Average daily weight gain and average daily feed consumption of pigs fed treatment 3 (100 g Heliotropium indicum leaf powder/kg diet), treatment 4 (200 g Heliotropium indicum leaf powder/kg diet) and treatment 5 (300 g Heliotropium indicum leaf powder/kg diet) were similar (p˃0.05) but significantly higher (p˂0.05) than those which received treatment 2 (0.25 g neomycin/kg diet) and treatment 1 (without Heliotropium indicum leaf powder/kg diet). Increase in the dietary supplementation of Heliotropium indicum leaf powder significantly decreased (p˂0.05) feed to gain ratio of pigs compared with treatment 2 and treatment 1.
Parameters | Treatment 1 | Treatment 2 | Treatment 3 | Treatment 4 | Treatment 5 | SEM |
Initial body weight (kg) | 9.09 | 9.08 | 9.06 | 9.07 | 9.06 | |
Final body weight (kg) | 17.21c | 19.58b | 24.10a | 24.45a | 24.67a | |
Average body weight gain (kg) | 8.12c | 10.50b | 15.04a | 15.38a | 15.61a | |
Average daily weight gain (kg) | 0.14c | 0.18b | 0.25a | 0.26a | 0.26a | |
Average feed consumption (kg) | 42.65c | 44.32b | 49.33a | 49.04a | 49.22a | |
Average daily consumption (kg) | 0.71c | 0.74b | 0.82a | 0.82a | 0.82a | |
Feed: gain ratio | 5.25a | 4.22b | 3.27c | 3.18c | 3.15c |
Values followed by different letters were significantly different (p˂0.05); treatment 1: basal/regular diet without Heliotropium indicum leaf powder (control); treatment 2 (Neomycin 0.25 g/kg diet), treatment 3, 4 and 5: basal diet supplemented with Heliotropium indicum leaf powder at 100 g, 200 g, and 300 g per kg respectively; SEM: standard error of mean.
Table 3: Growth performance of weaned rabbits fed with Heliotropium indicum leaf powder
Carcass characteristics of weaned rabbits fed with Heliotropium indicum leaf powder (Table 4). Carcass and dressing percentage follow similar trend as Heliotropium indicum leaf powder increased these parameters compared to the other groups. Dressing percentage values were lowest in treatment 1, intermediate in treatment 2 and highest in treatment 3, 4 and 5 (p˂0.05). Weights of head, back, fore limb, hind limbs, belly, kidney, lungs and heart were highest in treatments supplemented with Heliotropium indicum leaf powder (treatment 3, 4 and 5), intermediate in treatment 2 and lower in treatment 1 except for those values recorded for spleen which was not influenced (p˃0.05) by the treatment.
Variables (kg) | Treatment 1 | Treatment 2 | Treatment 3 | Treatment 4 | Treatment 5 | SEM |
Live weight (kg) | 18.06c | 20.76b | 25.87a | 25.90a | 25.98a | |
Carcass weight | 11.31c | 13.87b | 19.10a | 19.15a | 19.21a | |
Dressing percentage | 62.62c | 66.81b | 73.83a | 73.93a | 73.94a | |
Head | 2.41b | 2.67b | 3.39a | 3.42a | 3.48a | |
Back | 3.04b | 3.56b | 4.04a | 4.11a | 4.15a | |
Hind limb | 4.02b | 4.56b | 5.00a | 5.02a | 5.05a | |
Fore limb | 3.97b | 4.43b | 5.06a | 5.18a | 5.26a | |
Belly | 2.11b | 2.53b | 3.07a | 3.18a | 3.22a | |
Kidney | 0.03c | 0.12b | 0.19a | 0.20a | 0.21a | |
Lungs | 0.18b | 0.20b | 0.37a | 0.40a | 0.41a | |
Spleen | 0.03 | 0.04 | 0.04 | 0.04 | 0.04 | |
Heart | 0.16c | 0.25b | 0.42a | 0.48a | 0.49a |
Values followed by different letters were significantly different (p˂0.05); treatment 1: basal/regular diet without Heliotropium indicum leaf powder (control); treatment 2 (Neomycin 0.25 g/kg diet), treatment 3, 4 and 5: basal diet supplemented with Heliotropium indicum leaf powder at 100 g, 200 g, and 300 g per kg respectively; SEM: standard error of mean.
Table 4: Carcass characteristics of weaned rabbits fed with Heliotropium indicum leaf powder
The outcome on average daily body weight showed that pigs which received Heliotropium indicum leaf powder had higher values compared to the other group. This suggests that the presence of phytocomponents in Heliotropium indicum leaf powder could stimulate or enhance digestive enzyme activities and absorption of nutrients leading to a better nutrient utilization which in turn translates to a higher weight gain in pigs (Alagbe, 2024). Though there was similarity in average weight gain among pigs fed diet supplemented with Heliotropium indicum leaf powder (treatment 3, 4 and 5) followed by those which received neomycin (treatment 2) and lowest in treatment 1 suggesting that neomcycin was also an effective synthetic growth promoter. Previous reports by shown that phytocomponents in medicinal plants possess vital nutritional and medicinal properties (Singh et al., 2022; Ojediran et al., 2024a). The presence of flavonoids, tannins, alkaloids, saponins, triterpenoids, steroids, amthraquinones and glycosides in Heliotropium indicum leaf powder indicates multiple pharmacological functions such as, anti-inflammatory (Musa et al., 2020), antioxidant, antiviral, antifungal (Ojediran et al., 2024b), immune-stimulators (Adewale et al., 2021), gastro-protective (John, 2024e), anticancer, anti-diabetic, antimicrobial (Daniel et al., 2023), anti-helminthic, antidiarrheal (John, 2024d), antibacterial amongst others. Result on average weight gain was similar to the earlier report by (). Conversely, (Alagbe et al., 2024) found out supplementation of Heliotropium indicum leaf powder at 30 g/kg diet did not influence daily body weight of growing pigs. The discrepancies in results could be attributed to levels of supplementation, nature of bioactive compounds in the test material as well as method of preparation (Adewale et al., 2021). Increase in daily feed consumption especially among pigs fed with Heliotropium indicum leaf powder aligns with the notion that dietary supplementation of medicinal plants can improve palatability of diet thereby facilitating taste receptors in pigs. This result conforms to the earlier report by (John, 2024a; Omokore and Alagbe, 2019) when phytogenics was fed to growing rabbits. Feed to gain ratio which varied from 3.15 to 5.25 decreased as the level of Heliotropium indicum leaf powder increased in the diet of pigs suggesting efficiency in feed utilization in the treatment. This further reaffirms that phytocomponents in Heliotropium indicum leaf powder have the capability to stabilize gut against proliferation by pathogenic organisms (Shittu et al., 2024; John, 2024b). Result obtained is in agreement with the reports by Upadhaya (2016a, 2016b) who discovered that growing pigs fed blend of phytogenics had a feed to gain ratio of 3.23 - 5.50.
Dressing percentage are useful indices to determine meat yield in animals. Findings of this present study (62.62 to 73.94 %) was similar to the result of a study by Zhou et al. (2013) who showed that dressing percentage of growing pigs fed Coptis chinensis herb extract varied from 61.94 to 74.05 % as well as those reported by Yan et al. (2012) who discovered that dressing percentage of weanling pigs fed diet supplemented with Houttuynia cordata and Taraxacum officinale varied from 60.09 to 73.00 %. The present experiment revealed that weights of back, belly, fore limb, hind limb, kidney, lungs and heart was influenced by Heliotropium indicum leaf powder in the diet which was a result of the increase in dressing percentage. This result suggests that Heliotropium indicum leaf powder is non-toxic and can modulate the retention time of feed in the gastro intestinal tract of pigs (Muritala et al., 2022). Lei et al. (2018); Ao te al. (2020); Jeong and Kim (2015), discovered that weights of head, back, fore limb and hind limb varied from 2.00 - 3.80 kg, 3.00 -5.00 kg, 3.80 - 5.50 kg and 3.90 - 5.70 kg respectively in growing pigs fed diet supplemented with natural and fermented herbs. The higher values recorded in heart and lungs of pigs fed Heliotropium indicum leaf powder compared to the other group suggests sufficient supply of oxygen in the system of pigs (Olafadehan et al., 2020). The kidney plays a key role in the waste removal as well as extra water to make urine (John, 2024d). Supplementation of Heliotropium indicum leaf powder did not influence weight of spleen suggesting that the integrity of the immune system was not compromised (Daniel et al., 2023). Heliotropium indicum leaf powder is known to contain flavonoids which possess antioxidant properties and scavenging the activities of free radicals (Singh et al., 2022).
It was concluded that Heliotropium indicum leaf powder has both nutritional and medicinal properties. It also contains compounds that has no toxic side effects. Results on growth revealed that supplementing Heliotropium indicum leaf powder up to 300 g/kg had no deleterious effect on the growth performance as well as organs in the animal’s body. The supplementation of Heliotropium indicum leaf powder can also help to address multidrug resistance and promote food safety.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.