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Research Article | DOI: https://doi.org/10.31579/2693-4779/278
Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlanepantla, Mexico.
*Corresponding Author: Avila Hernández Nelly Julieta, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlanepantla, Mexico.
Citation: Avila Hernández Nelly Julieta, (2025), Association Between Covid-19 Vaccination and Alterations in The Menstrual Cycle, Clinical Research and Clinical Trials, 13(1); DOI:10.31579/2693-4779/278
Copyright: © 2025, Avila Hernández Nelly Julieta. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 30 May 2025 | Accepted: 16 June 2025 | Published: 20 July 2025
Keywords: COVID-19; vaccination; women; menstrual cycle; menstrual alterations; bleeding
The COVID-19 pandemic, declared in March 2020 by the WHO, prompted global health strategies, including mass vaccination campaigns. In record time, vaccines were developed with various biotechnological platforms (mRNA, viral vectors and inactivated viruses), which demonstrated high efficacy in reducing hospitalizations and deaths from SARS-CoV-2. Its adverse effects were mostly mild and transient. However, as immunization progressed, anecdotal reports emerged about possible alterations in the menstrual cycle, such as changes in the duration, intensity of bleeding, frequency between cycles and atypical premenstrual symptoms. Although in cases such as the HPV vaccine this possibility had already been raised, a direct causal relationship has not been established.
Objective: To analyze the possible association between vaccination against COVID-19 and menstrual alterations in Mexican university women.
Materials and methods: Observational, longitudinal and analytical study by means of a digital survey applied between August and December 2024 to women over 18 years of age, active or graduated from the FES Iztacala, with regular cycles and at least one dose of COVID-19 vaccine. Those who had factors that altered their menstruation were excluded. The survey collected general data, pre- and post-vaccination menstrual characteristics, lifestyle, and vaccine type.
Results: 59.8% of the participants reported menstrual alterations. The main changes were in bleeding intensity (82.6%), period length (55.4%), and frequency (31.5%). Physical and emotional symptoms were also reported.
Conclusions: The results suggest a possible temporal association without serious clinical consequences.
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, a type of coronavirus (Image. 1)
Image 1: Viral structure of the Coronavirus. Reproduced from "COVID-19, the viral disease that spread in the world" (Cedillo-Barrón, 2020).
(Table. 1) that mainly affects the respiratory tract and can cause flu-like symptoms. At the end of December 2019, in the city of Wuhan, China, multiple cases of pneumonia of unknown origin were reported, which were later attributed to this new viral agent. The high transmission capacity of the virus [1] —mainly through respiratory droplets and contaminated surfaces— led to its rapid spread worldwide, which triggered a health emergency in a short period of time.
| NAME: | "Coronavirus", Coronaviridae, subfamily Orthocononavirinae. |
| OF MEDICAL IMPORTANCE: | Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus. |
| VIRAL STRUCTURE: | Spherical structure (11-13nm in diameter) surrounded by an envelope with projections in the form of peaks or spikes, which gives them an appearance similar to that of a crown - hence their name coronavirus. |
| PROTEIN STRUCTURE: | They maintain a helically symmetrical capsid formed by the nucleocapsid protein (N) and are surrounded by a lipid envelope in which three proteins are found: protein E (envelope), protein M (membrane) and protein S (spike). |
| TRANSMISSION: | Respiratory droplets when coughing, talking or sneezing, aerosols, contaminated surfaces. |
| INCUBATION PERIOD: | 1-2 to 12 days. |
| COMMON SYMPTOMS: | Runny and runny nose, cough, fatigue, sore throat and headache, fever, chills and malaise, shortness of breath (dyspnea). |
| DIAGNOSIS: | Preliminary diagnosis: Present the picture of symptoms and have been exposed to contagion. Confirmatory diagnosis: By real-time RT-PCR. |
Note. Made from: Weiss-Leibowitz, (2020); Gibson (2022); Valverde-Temoche, (2021) [2-4]
| |
Table 1: General information about the Coronavirus.
The rapid spread of SARS-CoV-2 affected millions of people on all continents, causing the collapse of numerous health systems, profound economic disruptions, and significant transformations in social life. On March 11, 2020, the World Health Organization (WHO) officially declared COVID-19 a pandemic, with more than 118,000 cases in 114 countries and a growing number of deaths.[5]
Given the urgency to find effective solutions, care measures were implemented to stop the spread of the virus – such as confinement, mandatory use of face masks and distancing – which drastically modified social dynamics. Subsequently, the scientific community and technological development managed to authorize and distribute various vaccines from different pharmaceutical companies in less than a year around the world; This advance not only marked a key event in the history of vaccinology, but also demonstrated the potential of global scientific cooperation in the face of health emergencies.
In Mexico, according to the Ministry of Health, between 2020 and 2023, at least six waves of COVID-19 infections were recorded. Each one presented different clinical and epidemiological characteristics, evidencing changes in the transmission capacity of the virus, mainly due to the appearance of new variants, with Delta and Omicron being the most predominant in the population.[6] (Table 2) The vaccination process against COVID-19 in Mexico began in December of that same year (2020), with the application of the first doses to health personnel in Mexico City. The strategy was implemented in stages, prioritizing the most vulnerable groups and was extended by age phases until May 2022. As of March 2021, more than 75 million vaccines against COVID-19 had been administered in Mexico. Of these, 85%, that is, 64 million have a complete scheme, and 11 million have at least one dose, which represents 15%. [7
| VARIANT | PLACE OF IDENTIFICATION | GLOBAL CIRCULATION PERIOD | DESIGNATION ACCORDING TO IMPACT ON POPULATION | |
| Alpha | United Kingdom | December 2020 - mid-2021 | VOC | |
| Beta | South Africa | Late 2020 - Mid 2021 | VOC | |
| Gamma | Brazil | Early 2021 - Mid 2021 | VOC | |
| Delta | India | April 2021 - end of 2021 | VOI: April 2021 VOC: June 2022 | |
| Omicron | South Africa | November 2021 - present | VUM: November 2021 VOC: March 2023 | |
*Variant under monitoring (VUM): Investigate whether this variant may pose an additional threat to global public health. *Variant of interest (VOI): Describe a variant with changes that are known to affect the behavior of the virus and its potential impact on people's health (increased ability to spread). *Variant of concern (VOC): This is a variant defined as VOI but also meets the following criteria: a.) It can cause a detrimental change in the severity of the disease. b.) can have a substantial impact on the ability of health systems to care for COVID-19 patients. C.) significant decrease in the effectiveness of available vaccines to protect against severe disease. | ||||
| Note. Adapted from: Historical working definitions and primary actions for SARS-CoV-2 variants, 2023. [8] | ||||
Table 2: Variants of the SARS-CoV-2 virus that occurred during the pandemic.
Vaccines, as fundamental tools in health care, represent an immunological strategy that allows the body to generate specific defenses against infectious agents without exposing itself to the effects of the disease. In the context of the COVID-19 pandemic, the different vaccine platforms (mRNA, viral vectors, inactivated viruses, and protein subunits) demonstrated high efficacy in preventing severe forms of the disease (95%–85%) depending on the dosage regimen and population. (5, 6, 7) (Table 3)
| VACCINES | DIGITAL PLATFORM | MECHANISM OF ACTION |
| Pfizer-BioNTech and Moderna | Messenger RNA (mRNA) | They introduce genetic instructions for cells to produce the virus's S protein, triggering an immune response. |
| AstraZeneca, Sputnik V, Janssen and Patria | Non-replicating viral vector | They use a harmless modified virus to carry genetic information from SARS-CoV-2. |
| Sinovac | Inactivated virus | It contains the complete virus that has been inactivated (killed) although it cannot cause disease, the immune system recognizes it and generates defenses. |
| Abdala and Soberana* | Protein subunit | It includes specific fragments of the virus (such as the S protein) along with adjuvants that enhance the immune response. |
| *The Abdala, Soberana 02 and Soberana Plus vaccines are vaccines that have been produced externally but have been authorized for use in Mexico. | ||
| Note. Made from: "Vaccine Information," Ministry of Health, Mexico. [12]. | ||
Table 3: Types of COVID-19 vaccine authorized and applied in Mexico and their mechanism of action.
Due to the little experience with these vaccines, the health authorities established a surveillance system from the beginning to identify possible adverse effects. Although most of the reported symptoms were mild and temporary — such as pain at the injection site, fever, fatigue, headache, muscle aches —[13,14] the speed of the process also showed less common side effects, particularly with regard to variables related to female reproductive health, as testimonies began to emerge related to changes in the duration, frequency and characteristics of their menstruation after receiving one of the vaccines against COVID-19.
The lack of scientific studies at the Mexican population level on the relationship between the vaccine and the modification of menstrual cycles reduces the ability to address the concerns expressed and provide adequate guidance to menstruating people regarding the possible effects of vaccination. Therefore, the objective of this study is to analyze whether there is an association between the application of the COVID-19 vaccine and menstrual alterations in Mexican university women, particularly those linked to the university community of the Iztacala Faculty of Higher Studies
2.1 Type And Design Of The Study
According to the Supo taxonomy (2012) [15], the present study corresponds to an observational, longitudinal, analytical and prospective design, with a relational level of research.
2.2 Population And Sample
The population was composed of Mexican women between 19 and 35 years old, active or graduated from a bachelor's degree from the Iztacala Faculty of Higher Studies (UNAM).
A simple random sampling was used with a convenience technique, recognizing the possibility of self-selection bias, since participation was voluntary and through an online form. To reduce biases, strict inclusion and exclusion criteria were established (Table 4), and any participant with a history that could affect their menstrual pattern was excluded.
The sampling was random, with a convenient technique.
2.3 Inclusion And Exclusion Criteria
These were defined based on literature that points to various factors capable of modifying the menstrual cycle, such as the use of contraceptives, emotional alterations or hormonal disorders.[16].
Data collection was carried out through a digital survey of our own elaboration, not standardized, specifically designed according to the objectives of this study. The questionnaire was implemented through the Google Forms (https://forms.gle/grS5p2YiV2jXiGez6) platform under the title "Association between the COVID-19 vaccine and alterations in the menstrual cycle of students of the Iztacala Faculty of Higher Studies". The dissemination of the instrument took place between August and December 2024, through social networks such as Facebook, Instagram and WhatsApp. The survey was made up of eight sections:
The instrument used was previously validated by expert judgment, in order to ensure its conceptual relevance and clarity in the wording of the items. Subsequently, an internal consistency analysis was performed using Cronbach's alpha coefficient, obtaining a value of 0.932, which indicates a statistically excellent reliability. However, the questionnaire did not incorporate objective clinical indicators or validated psychometric scales for the assessment of specific emotional symptoms, such as anxiety or depression.
In the development of the research, the ethical and legal principles that govern the participation of human beings in academic studies were fully respected. Each participant was duly informed about the objectives, procedures, expected benefits and possible risks of the study, thus guaranteeing their right to make free and conscious decisions about their participation. As a fundamental part of the ethical process, each participant signed a digital informed consent, which recorded voluntary participation, the possibility of withdrawing at any time without consequences, the confidentiality of the information provided and the exclusive use of the data for academic and scientific purposes. In this way, compliance with the ethical standards of respect, autonomy and confidentiality in the treatment of information was ensured.
Using the IBM SPSS Statistics software platform, an internal validation analysis was performed, which included construct and reliability analysis of the instrument, obtaining a Cronbach's alpha of 0.932, which indicated excellent reliability. Subsequently, a descriptive analysis was applied using measures of frequency, central tendency and variability. For the inferential analysis, the Chi-square test of Independence was used. A value of p ≤ 0.05 was considered statistically significant.
Due to the exploratory nature of the study, non-probabilistic convenience sampling was used. Participation was voluntary and only those people who met the inclusion criteria and completed the survey in its entirety during the data collection period were considered. In this context, data from 176 Mexican women in an average age range of 19 to 35 years (mean age 22.98) were analyzed. Most of the responses came from residents of Mexico City (48.3%) and the State of Mexico (46.6%), which together represented 94.9% of the sample.
Following the exclusion criteria1, the following were excluded from the total (n=176) (Table 4)
Thus, the final sample was composed of 92 women who met the inclusion criteria.
| PARTICIPANTS | INCLUSION CRITERIA | EXCLUSION CRITERIA 1 |
|
| |
| n= 176 | n= 92 | n= 84 |
| Note. 1 These were defined based on literature that points to various factors capable of modifying the menstrual cycle, such as the use of contraceptives, emotional alterations or hormonal disorders.[17]. | ||
Table 4: Participating population based on inclusion and exclusion criteria.
Of the 100% of the population, 39.2% of the women who responded to this survey are graduates and 60.8% are studying one of the bachelor's degrees taught at the Iztacala Faculty of Higher Studies, of which nursing (47.7%), psychology (21.6%) and medicine (10.8%) are the careers in which there were the largest number of participants.
Distribution of vaccines applied
Of the sample analyzed (n=92) and who reported having been vaccinated against COVID-19, the following were applied: I. Messenger RNA vaccines 27.2% (n=25): such as Pfizer-BioNTech 15.2% (n=14) and Moderna 12% (n=11). II. Viral vector vaccines 65.2% (n=60): AstraZeneca 21.7% (n=20), Sputnik V 42.4% (n=39) and Janssen with 1.1% (n=1) and III. Vaccines with inactivated virus such as Sinovac with 7.6% (n=7). (Table 5). Regarding the dosage schedule, 64.1% have a complete dose schedule (3-4 doses), 34.8% with 1-2 doses and only one person (1.1%) reports having received a 5th dose. (Table 6.)
| VACCINE | FREQUENCY | PERCENTAGE | VALID PERCENTAGE | CUMULATIVE PERCENTAGE | |
| VALID | PFIZER BIONTECH | 14.0 | 15.2 | 15.2 | 15.2 |
| ASTRAZENECA | 20.0 | 21.7 | 21.7 | 36.9 | |
| SPUTNIK V | 39.0 | 42.4 | 42.4 | 79.3 | |
| SINOVAC | 7.0 | 7.6 | 7.6 | 86.9 | |
| JANSSEN | 1.0 | 1.1 | 1.1 | 88.0 | |
| MODERN | 11.0 | 12.0 | 12.0 | 100.0 | |
| 92.0 | 100.0 | 100.0 |
Table 5. Distribution of vaccines applied as first and second doses.
| DOSE | FREQUENCY | PERCENTAGE | VALID PERCENTAGE | CUMULATIVE PERCENTAGE | |
| VALID | 1-2 DOSES | 32 | 34.8 | 34.8 | 34.8 |
| 3-4 DOSES | 59 | 64.1 | 64.1 | 98.9 | |
| 5 OR MORE DOSES | 1 | 1.1 | 1.1 | 100.00 | |
| 92.0 | 100.0 | 100.0 |
Alterations in the menstrual cycle
Table 6. Distribution of application of dosage schedule.
After the administration of the COVID-19 vaccine, 59.8% (n=55) of the women surveyed consider that there were alterations in their menstrual cycle. Specifically, 55.4% (n=51) of the women reported changes in the duration of menstruation, 31.5% (n= 29) in the frequency between cycles, and 82.6% (n=76) in bleeding intensity. After comparing the menstrual pattern of the participants prior to vaccination with the changes reported after vaccination, significant differences were recorded in the duration of menstruation (p=0.000), the frequency between cycles (p=0.000) and the intensity of bleeding (0.001). (Table. 7).
| REPORTED CHANGES | VALUE OF SIGNIFICANCIA1 | |
| DURATION OF MENSTRUATION | .000 | |
| FREQUENCY BETWEEN CYCLES | .000 | |
| INTENSITY OF BLEEDING | .001 | |
| Note. 1 Chi-square test of independence – Statistical significance value p ≤ 0.05 | ||
Table 7. Comparison between normal menstruation pattern versus changes reported after COVID-19 vaccinationWhen comparing the intensity of physical and psychoemotional symptoms before and after COVID-19 vaccination, significant changes were observed in the significance variables (p<0>emotional symptoms, significant differences were found before vaccination in anxiety (p=0.005), depression (p=0.002), crying (p=0.046), mood swings (p=0.009), anger (p=0.001), appetite change (p=0.007) and changes in libido (p=0.035). In the post-vaccination period, only crying (p=0.033), insomnia (p=0.030), and lack of concentration (p=0.001) were present. In physical symptoms, prior to vaccination, differences were found in breast sensitivity (p=0.000), acne (p=0.000) and constipation (p=0.003). In the post-vaccine period, significance was observed in headache (p=0.011), weight gain (p=0.036), abdominal swelling (p=0.013), breast tenderness (p=0.018) and diarrhea (p=0.000) (Table 8)
| BEFORE AND AFTER MENSTRUATION | PRE-VACCINE | POST-VACCINE | |
| EMOTIONAL | ANXIETY | .005 | .858 |
| DEPRESSION | .002 | .579 | |
| CRYING | .046 | .033 | |
| IRRITABILITY | .203 | .310 | |
| MOOD CHANGE | .009 | .359 | |
| ANGER | .001 | .178 | |
| APPETITE CHANGE | .007 | .346 | |
| INSOMNIA | .675 | .030 | |
| SOCIAL ISOLATION | 1.000 | .436 | |
| LACK OF CONCENTRATION | .346 | .001 | |
| CHANGES IN LIBIDO | .035 | .650 | |
| PHYSICAL | NAUSEA, DIZZINESS | .458 | .263 |
| HEADACHE | .290 | .011 | |
| FATIGUE | .428 | .916 | |
| WEIGHT GAIN | .366 | .036 | |
| ABDOMINAL BLOATING | .379 | .013 | |
| BREAST SENSITIVITY | .000 | .018 | |
| ACNE | .000 | .053 | |
| CONSTIPATION | .003 | .087 | |
| CRAMPS | .949 | .712 | |
| DIARRHOEA | .826 | .000 | |
| COLITIS | .225 | .752 | |
| Note. 1 Chi-square test of independence – Statistical significance value p ≤ 0.05 | |||
Table 8: Symptoms related to the menstrual cycle: Comparison between pre-vaccine and post-vaccine symptoms.
The rapid production and distribution of biologics against COVID-19 as a strategy to face the global health emergency limited the time available to comprehensively evaluate their possible side effects in different population groups, particularly women. Historically, similar concerns have been documented about the possible influence of certain immunogens on the menstrual cycle. Such is the case of the vaccine against the human papillomavirus (HPV) reported in 2013[18] , the typhoid vaccine in 1913 and the Hepatitis B vaccines in the mid-80s. (13,14) These studies agree that these modifications tend to be mild and transient and a conclusive cause-and-effect relationship has not been found, so they do not imply a long-term risk or affect fertility.
Although the physiological mechanisms involved are not yet fully understood, several studies have documented transient modifications in the menstrual cycle associated with vaccination. For example, research published in JAMA Network Open (18) identified slight (<1>
The data obtained in this research show that a considerable proportion of the participants manifested menstrual alterations after receiving the COVID-19 vaccine: Approximately 6 out of 10 participants experienced modifications in their menstrual cycle. The most frequent changes included variations in bleeding intensity (82.6%), period length (55.4%), and frequency between cycles (31.5%). The fact that more than half of women experienced some modification in their menstruation underscores the importance of including menstrual health as a component in post-vaccination surveillance, especially considering the emotional and physical impact these changes can have on women's quality of life.
Although the reported symptoms do not imply serious clinical consequences, their frequency and distribution allow us to observe a possible common response at the population level. In addition, the magnitude of the effects reported in this sample seems slightly higher than that observed in other national studies, for example, in a cross-sectional study carried out at the ABC Hospital in Mexico City it showed that 48.1% of vaccinated women reported some menstrual alteration. Among the most frequent were menorrhagia (20.7%) and increased menstrual pain (27.4%).[19] In this context, the results of this study provide additional evidence from a specific population – Mexican university women – that until now has been underrepresented in the scientific literature.
From an emerging perspective, research has emerged that has begun to explore the role of regulatory proteins such as Sirtuin 1 [20] involved in key cellular functions, including hormonal stability. It has been suggested that this protein may be affected by SARS-CoV-2 and, possibly, by the immunological stimuli associated with vaccination, which opens up new routes to understand menstrual alterations from a molecular approach. Although this line is still in its infancy, it could have therapeutic implications in the future.
In short, although the documented menstrual alterations seem transitory, it is essential that they are recognized and incorporated into post-vaccination surveillance systems because the menstrual cycle is a sensitive indicator of body balance, and their study contributes not only to improving the quality of clinical follow-up, but also to strengthening the confidence of the female population in immunization campaigns.
The results of this study support the existence of a temporal association between vaccination against COVID-19 and alterations in the menstrual cycle in Mexican university women. The main modifications reported included variations in bleeding intensity, period length, and frequency between cycles, with statistical significance. Although these alterations do not imply a serious clinical risk nor have they been shown to affect fertility, they can produce significant functional, emotional and social impact that should not be underestimated. Its high prevalence in the sample analysed highlights the importance of including menstrual health as part of post-vaccination pharmacovigilance, especially in young populations and those of reproductive age in order not to generate alarm or reduce confidence in vaccination campaigns.
This study has several limitations that must be considered when interpreting its results. First, the observational and cross-sectional design, based on a self-administered survey, carries an inherent risk of memory bias and subjectivity in the responses, since it depends exclusively on the individual perception of the participants regarding the changes in their menstrual cycle. Objective clinical measurements were not included, such as hormone levels, ultrasounds, or gynecological evaluations, that would validate the symptoms reported from a biomedical point of view.
Likewise, the lack of longitudinal follow-up represents an important limitation, since it was not possible to evaluate the duration, recurrence or resolution of menstrual alterations over time. The research was conducted retrospectively, without collecting data at the time the changes occurred, which may have affected the accuracy of the information obtained.
Another relevant aspect is the variability in exposure conditions. The participants received different types of vaccines (with different biotechnological platforms), at different times of the cycle and with variable intervals between doses, which makes it difficult to establish a clear relationship between a specific biological and the alterations observed. In addition, each dose was considered as a unit of exposure, without homogeneity at the time of application or control over previous hormonal factors, which introduces heterogeneity in the risk periods evaluated.
The sample was made up exclusively of young women, university students and belonging to a single academic institution (FES Iztacala – UNAM), which restricts the generalization of the findings to other population groups, such as older women, women with pre-existing gynecological conditions or from diverse socioeconomic contexts. The use of convenience sampling may also have generated self-selection bias, since those who experienced menstrual alterations were able to feel more motivated to participate in the survey. On the other hand, the exclusion of women with emotional disorders, inadequate diet, or hormonal diseases – conditions that are common during the pandemic – reduces the possibility of observing how these factors interact with the effects of vaccination on the menstrual cycle. Finally, the absence of a control group (unvaccinated women or women with different schedules) prevents direct comparisons that allow a stronger association between immunization and menstrual changes to be established.
Taken together, these limitations underscore the need for larger studies, with long-term follow-up, objective clinical assessment, and diverse population representativeness, in order to better understand the relationship between COVID-19 vaccines and menstrual health.
There is no conflict of interest.
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We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
