Anemia among under five years of age suffering from malnutrition in Sana’a city, Yemen

Research Article | DOI: https://doi.org/10.31579/2690-4861/727

Anemia among under five years of age suffering from malnutrition in Sana’a city, Yemen

  • Ahmed Mohammed Al-Haddad 1
  • Hajar Razzaz Qaid Saif Alhaj 2
  • Amel Abdullah Almagrami 2,5
  • Khaled Abdulkarim Al-Moyed 3
  • Hassan Abdulwahab Al-Shamahy 3*
  • Ibrahim Ali Al-Arashi 5

1Department of Medical Laboratories, College of Medicine and Health Sciences, Hadhramout University, Al-Mukalla, Republic of Yemen.

2Yemeni Board for Medical and Health Specialties, Ministry of Health and Population, Republic of Yemen.

3Medical Microbiology and Clinical Immunology Department, Faculty of Medicine and Health Sciences, Sana’a University, Republic of Yemen.

4National center of Central Public health Laboratories, Ministry of Health and Population.

5Medical Microbiology and Clinical Immunology Department, Faculty of Health Sciences, Thamar University, Republic of Yemen.

*Corresponding Author: Hassan A. Al-Shamahy, Medical Microbiology and Clinical Immunology Department, Faculty of Medicine and Health Sciences, Sana’a University, Republic of Yemen.

Citation: Al-Haddad AM, Saif Alhaj HRQ, Amel A. Almagrami, Al-Moyed KA, Al-Shamahy HA, et al, (2025), Anemia among under five years of age suffering from malnutrition in Sana’a city, Yemen, International Journal of Clinical Case Reports and Reviews, 24(4); DOI:10.31579/2690-4861/727

Copyright: © 2025, Hassan A. Al-Shamahy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 03 March 2025 | Accepted: 18 March 2025 | Published: 27 March 2025

Keywords: anemia; malnutrition; pre-school children; sana’a; yemen

Abstract

Background: Anemia, a condition characterized by low red blood cell count or hemoglobin levels, is a significant public health issue, particularly among undernourished children under five years of age. Anemia is a significant public health problem in many low- and middle-income countries, with young children being especially vulnerable. In almost every nation on Earth, a sizable portion of the populace suffers from anemia. 

Objective: The main objective of this study was to assess the prevalence of anemia and identify other blood parameters among children under five years suffering from malnutrition.

Methods: A cross-sectional study was carried out among 50 children from Sana’a city suffering from malnutrition from 1st of October 2023 until the end of February 2024. Data on socio-demographic, dietary, blood samples for hemoglobin level, and other blood markers were collected and then tested by automated methods.

Results: The study included 36% males and 64% females, with a mean age of 11.8 months and a range of 1-60 months. The mean RBC count was 4.2 cells x 106/μl with a SD of 0.72 and ranged from 2.6 to 5.5 cells x 106/μl. The mean WBC count was 10.3 cells x 109/L with an SD of 4.3 and ranged from 2.8 to 24 cells x 109/L. The mean hemoglobin level was 10.4 mg/dL and ranged from 6.2 to 12.9 mg/dL. (<11.1 mg/dL) was reported in 54% of all malnourished children. 

Conclusion: The prevalence of anemia in children under five years is a pressing public health issue that necessitates urgent attention in the study area. The most important predictors are suboptimal child feeding practices, food insecurity, and a poor diet. Multi-sectoral efforts are needed to improve health, and interventions targeting nutritional security are recommended.

1.Introduction

Anemia where there is a deficiency in red blood cells or the hemoglobin concentration within them falls below the normal levels [1]. This blood disorder, characterized by a reduced hemoglobin level, poses a significant public health threat to individuals in both developed and developing nations [2, 3]. 

Anemia in children under five years of age is a significant public health concern globally, particularly in low- and middle-income countries. It is characterized by a reduction in hemoglobin levels, which can lead to various health complications, including impaired cognitive and physical development, increased susceptibility to infections, and higher mortality rates. The World Health Organization (WHO) estimates that approximately 43% of children under five are affected by anemia, with iron deficiency being the most prevalent cause [4, 5].

Anemia is a significant global health concern, affecting millions of individuals worldwide. In 2019, an estimated 30% of non-pregnant women and 37% of pregnant women aged 15-49 years were anemic, representing 539 million and 32 million women, respectively [6, 7]. Furthermore, a substantial proportion of children under five years old face nutritional challenges: 149 million are stunted, 45 million are wasted, and 38.9 million are overweight or obese in 2020 [3]. 

These figures underscore the urgent need for global efforts to address anemia and improve nutritional outcomes for vulnerable populations. Research from various studies consistently identifies multiple factors contributing to anemia within vulnerable populations. In developing countries, iron deficiency stands out as a primary cause, often accompanied by factors like malaria, parasitic infections, nutritional deficiencies, and genetic conditions such as hemoglobinopathies [4, 5, 6, 7].

Iron deficiency serves as the leading factor behind anemia, which is why anemia prevalence is frequently used as a proxy for insufficient iron levels. Iron deficiency anemia (IDA) and anemia are hence used interchangeably [8]. Cognitive performance decline has been associated with iron-deficient anemia. Symptoms like weakness, fatigue, difficulty concentrating, and decreased work capacity can result from impaired tissue oxygen supply. Children, in particular, may face challenges in their mental and physical growth. Severe IDA may predispose individuals to infections and heart failure and increase the risks of preterm labor, low birth weight, and maternal and child mortality [9, 10].

Yemen's situation is dire, with an estimated 47% of children under five experiencing stunting and 15% suffering from wasting, showcasing the country's severe chronic malnutrition crisis [11]. The United Nations estimates that 22.2 million Yemenis are in need of humanitarian aid. Approximately 16.4 million individuals lack access to quality healthcare, and 17.8 million people grapple with food insecurity. Around 462,000 children are affected by severe acute malnutrition, and 1.8 million children suffer from acute malnutrition [12]. Due to escalating violence in Yemen, approximately 2 million people are being forcibly displaced from their homes at alarming rates, according to reports [13].

According to data from Ministry of Public Health and Population, the prevalence of anemia among children under five in Yemen saw a significant increase, despite a decrease from 54% in 2005 to 40% in 2011 [13]. The government's inaction in addressing the escalating anemia rates poses a serious public health challenge in Yemen. To determine the prevalence of anemia among malnourished children aged 6-60 months in Sana'a, Yemen, along with associated factors, a study was conducted. The WHO defines anemia variations based on factors such as altitude, race, smoking status, age, sex, and pregnancy status: Hb level < 11g>

Internally displaced persons are dispersed within communities and are challenging to identify or assess due to the absence of dedicated camps for them. Even before the conflict intensified in March 2015, Yemen faced considerable humanitarian needs [15]. Nearly 100,000 children under five in Hodeida are at risk of severe acute malnutrition, a stark increase from 23,000 before 2015. In Aden, this number has more than doubled from 3000 before 2015 to 7700 presently [16].

The objective of this cross-sectional study was to assess the prevalence of anemia and identify the contributing factors among malnourished children in Sana'a city, Yemen.

2. Subjects and Methods

2.1. Study design

This cross sectional active laboratory study was carried out in the children malnutrition centers in Sana'a, Yemen in the period from 1st of October 2023 until the end of February 2024.

2.2. Sample size

A sample size of 50 was calculated using the following parameters: confidence level = 95%, margin of error = 13.8%, and frequency of anemia among malnourished children = 54% [pilot study].

2.3. Data collection

Individual data were collected in a pre-designed questionnaire, including nutritional statistics, clinical data, demographic data, and laboratory results.

2.4. Statistical analysis

By using Epi Info statistical program version 6 (CDC, Atlanta, USA), the analysis of the data was performed. Expressing the quantitative data as mean values, or standard deviation (SD), when the data was normally distributed. Expressing the qualitative data as percentages.

2.5. Ethical consideration

Prior to gathering data, the institution's ethical review committee gave its approval. All participants or/and their guardians received an explanation of the study's goals and advantages prior to involvement, and their verbal informed agreement was obtained. Participants and their families were also told that their participation was optional and that they might decline it without giving a reason.

3. Fields and Laboratory Works

First clinical investigations of malnutrition was done by doctors in the hospitals and recorded in the pre-designed questionnaire. Then, a venous blood sample were taken for blood parameters testing with standard laboratory methods. 

4. Results

The male children counts 36% and female children was 64%. The mean age of our patients was 11.8 months with SD equal to 12.1 months and ages ranged from 1-76 months. Most of our patients were in the age group of 7-12 months (44%), followed by the group of 1-6 months (28%), while other age groups were less frequent (Table 1). The mean RBC count was 4.2 cells × 106/μl with a SD of 0.72 and ranged from 2.6 to 5.5 cells × 106/μl. The result showed that 36% of our patients had a value lower than normal for children. Most of our patients were at 4.0-4.9 cells x 106/μl (44%) followed by 20% for a level of >4.9 (Table 2). Table 3 shows the mean WBC count was 10.3 cells × 109/L with an SD of 4.3 and ranged from 2.8 to 24 cells × 109/L. The result showed that 4% of our patients had a value lower than normal for children. Most of our patients were at 4.5-10 cells x 109/L (54%) followed by 34% for a level of ≥11.1. The mean hemoglobin level of the children patients was 10.4 mg/dL, the SD level was 1.6 mg/dL and ranged from 6.2 to 12.9 mg/dL. Anemia (<11>40 PCV (Table 5). Table 6 shows the mean MCV was 75.9 fl with SD equal to 8.3fl, and the MCV ranged from 52 fl to 91 fl. Most patients had <80>84 fl. Table 7 illustrates the mean corpuscular hemoglobin/picograms (pg) per cell (MCH) of our patients was 24.6 p/cell, with standard division of 3.3 p/cell and ranged from 18 to 37 pg/cell. Most patients had less than 27 pg/cell (826%) indicating iron deficiency anemia while 6% had 27-28 pg/cell and 12% had more than 28 p/cell indicating anemia due to low levels of folic acid or vitamin B12. The mean MCHC of our patients was 32 g/dl, with SD of 2.1 g/dl and ranged from 29 to 37 g/dl. About 58% of patients had less than 32 g/dL anemia while 16% had 32-33.9 g/dL and 26% had >33.9 g/dL (Table 8). The mean RDW for our patients was 14.9%, with an SD of 2.3% and ranged from 10 to 22%. About 4% of patients have a level of <12> 16 level. All of these findings indicate anisocytosis which is common in nutritional anemia (Table 9). The mean platelets counts for our patients was 372.2 cell x 109/L  with an SD of  183.7 cell x 109/L  and ranged from 16 to 883 cell x 109/L. About 4% of patients have a level of <150>

CharactersN (%)
Sex
Male18 (36)
Female32 (64)
Age groups (months)
1-614 (28)
7-1222 (44)
13-2413 (26)
25-363 (6)
>361 (2)
Total50 (100)
Mean age11.8 months
SD12.1months
Median10 months
Mode12 months
Min-Max1-76 months

Table 1: Sex and Age distribution of children under five years with malnutrition in Sana’a city, Yemen.

RBC (cell x 106/μL)N (%)
Less than 4.018  (36)
4.0-4.922 (44)
>4.910  (20)
Total50 (100)
Mean4.2
SD0.72
Median4.2
Mode3.5
Min-Max2.6-5.5

A normal RBC count would be in children around 4.0 to 5.5 x 1012/L.

Table 2: Red blood cell counts of malnutrition children in Sana’a city, Yemen. (106/μL)

WBC (cell x 109/L )N (%)
Less than 4.5 2 (4 )
4.5-10.027 (54 )
10.1-11.04  (8 )
≥11.117 (34)
Total50 (100)
Mean 10.3
SD4.3
Median9.6
Mode6.4
Min-Max2.8-24

A normal WBC count would be in children around 4.5 to 11.0 x 109/L.

Table 3: White blood cell counts of malnutrition children in Sana’a city, Yemen (106/μL)

Hb (mg/dL )N (%)
Less than 10 18 (36)
10-11 9 (18)
11.1-1213 (26)
12.1-1310 (20)
>130 (0.0)
Total50 (100)
Mean 10.4
SD1.6
Median10.8
Mode10.7
Min-Max6.2-12.9

The normal Hb level for children (males and females) is 11.9 to 15 g/dl

Table 4: Hemoglobin level of malnutrition children patients

PCVN (%)
Less than 30.0 14 (28)
30-3520 (40)
35.1-40.012 (24)
>40.04 (8)
Total50 (100)
Mean 31.9
SD5.3
Median31.4
Mode31
Min-Max17-42.7

Normal levels of PCV in children range from 30% to 44%.

Table 5: Packed cell volume level of malnutrition children in Sana’a city, Yemen.

MCV /fl (Mean corpuscular volume/femtoleter) N (%)
Less than 80 32 (64)
80-8410 (20)
>848 (6)
Total50 (100)
Mean 75.9
SD8.3
Median77
Mode69
Min-Max52-91

Below 80 fl (femtoliters), they will likely develop or have microcytic anemia. Alternatively, if their MCV levels are greater than 100 fl, they could experience macrocytic anemia.

Table 6: MCV level of malnutrition children, Sana’a city, Yemen.

MCH (mean corpuscular hemoglobin/picograms per cell)N (%)
Less than 27 41 (82)
27-283 (6)
>286 (12)
Total50 (100)
Mean 24.6
SD3.3
Median24
Mode24
Min-Max18-37

Table 7: MCH level of malnutrition children, Sana’a city, Yemen.

The normal range for MCH is 27 to 31 picograms per cell. Anything above or below that may indicate an underlying condition, usually a type of anemia. Low levels of MCH can indicate iron-deficiency anemia while high levels of MCH can signal anemia caused by low levels of folic acid or vitamin B12. mean corpuscular hemoglobin

MCHC g/dlN (%)
Less than 3229 (58)
32-33.98 (16)
>33.913 (26)
Total50 (100)
Mean 32
SD2.1
Median31
Mode31
Min-Max29-37

Table 8: MCHC level of malnutrition children, Sana’a city, Yemen.

A typical MCHC result is 32-36 grams/deciliter (g/dL) or 320–360 grams per liter (g/L), although this may vary depending on the lab. Levels outside this range can indicate anemia.

RDW percentN (%)
Less than 122 (4)
12-1531 (62)
15-168 (16)
>169 (18)
Total50 (100)
Mean 14.9
SD2.3
Median15
Mode13
Min-Max10-22

Table 9: Red cell distribution width level of malnutrition children, Sana’a city, Yemen.

A normal range for red cell distribution width is 11.8 to 14.5 percent in children.

platelet count (cell x 109/L )N (%)
Less than 150 4 (8)
150-35020 (40)
351-45014  (28)
≥45112 (24)
Total50 (100)
Mean 372.2
SD183.7
Median359.5
Mode345
Min-Max16-883

A normal platelet count ranges between 150-450x109/L

Table 10: Platelets Counts of malnutrition children in Sana’a city, Yemen (109/L)

5. Discussion

A person is considered to be malnourished if their energy and/or certain nutrients are inadequate, excessive, or out of balance for their needs [17]. It's among the biggest issues that humanity is now dealing with. Malnutrition is caused in large part by variables such as poverty, regional conflicts, inadequate food supply, fast population increase, and social, political, and educational issues—all of which are present in Yemen. Anemia is considered to be harmful to one’s health, especially for mothers during pregnancy and young children [18, 19]. The youngsters would therefore be more susceptible to a range of infectious illnesses, including malaria and helminthic infections—all of which are common in Yemen [20].

Additionally, infections worsen malnutrition by lowering appetite, triggering catabolism, and raising nutritional requirements. Well-established research suggests that malnourished children are more likely to die from an infection, even if it is debatable whether malnutrition causes infections more frequently or just makes them worse [21,22]. Global estimates for 2020 indicated that 149 million children under five were stunted (too little for their age), 45 million were wasted (too thin for their height), and 38.9 million were overweight or obese [23]. As per the assessment on the status of food security and nutrition, 40% of Yemeni children were found to be undernourished, with 16% experiencing severe malnutrition and 41% experiencing stunting.

Fifty two million of the children under five had a mortality rate of 45%, according to the research [24]. This suggests that Yemen and other developing countries are susceptible to malnutrition [25]. One of the main causes of disease and death in preschool-aged children is under nutrition [26]. The malnourished young patients in this study had a mean hemoglobin level of 10.4 mg/dL, with a standard deviation of 1.6 mg/dL and a range of 6.2 to 12.9 mg/dL. Of all patients, 54% had anemia (<11>

The RBC count in this study varied from 2.6 to 5.5 cells x 106/μl, with a mean of 4.2 cells × 106/μl and a standard deviation of 0.72. The outcome demonstrated that 36% of our patients had values below the typical range for kids. As a result, variables that may contribute to the development of anemia include those that reduce red blood cell formation, increase their loss or destruction, or, in certain situations, both [30]. Over one-third of the world's population suffers from anemia, a public health issue that affects both industrialized and developing countries. However, in developing nations like Yemen, it is higher. Anemia is the most common hematologic symptom, according to a WHO publication [31]. Globally, the prevalence of anemia in children aged 6 to 59 months was 39.8% in 2019, which translates to 269 million children suffering from anemia. This percentage is lower than our 54% rate. In children under five, the frequency of anemia was highest in the African Region (60.2%) [32]. Anemia's effects on a nation's social and economic development are influenced by its lowering of immunity, which leaves youngsters more susceptible to infectious diseases and increases their risk of death [33]. Furthermore, it has been connected to stunted growth, lower psychomotor growth, and decreased social, emotional, and cognitive functioning in children [34]. These are serious effects for children as their bodies mature. 

The results of this study indicated that 54% of children under five had anemia overall. Following adjustments for a variety of socioeconomic and demographic factors, care-related factors, environmental health and sanitation, dietary and household food modifications, household food insecurity, and morbidity-related factors, it was found that anemic children were more likely to reside in households experiencing food insecurity, have a diet lacking in diversity, initiate supplemental feedings either early or late, receive subpar breast milk, and have mothers who used less iron and folate during their pregnancies. The WHO categorized the prevalence of anemia in children found in this study as a serious public health concern [3].

When comparing the prevalence of anemia and related variables in children with earlier international research, the frequency in this study was greater than Ethiopia's in the 2016 regional report (49.6%). This could be the result of food scarcity brought on by war, which lowers consumption of a variety of foods and causes disorders linked to micronutrient deficiencies, like anemia [35]. However, it was significantly lower than the 72.7% national survey for Ethiopia as a whole done in 2016 [36] and the 66.6% research carried out in the Wag-Himra zone in north Ethiopia [37]. Even so, it was far lower than research from Cameroon [38] and Sudan [39], where the frequency was 86% and 66.7%, respectively. The reduced prevalence in this study could be attributed to various variables, such as changes brought about by current nutritional practices, public health programs, and the ease with which health information can be accessed through health extension workers. However, with this tiny cross-sectional study, the sample size is still insufficient to compare with the national data of the EDHS; hence, large sample sizes and analytical investigations are required to understand temporal and seasonal differences.

6. Conclusion

This study determined that the prevalence of anemia among children under five years old in Sana’a city, central Yemen, was 54%. Such prevalence is categorized as a severe public health concern by WHO classification criteria. Initiation time of complementary feeding, breast feeding practice, maternal history of iron folate (IFA) utilization, dietary diversity, and household food insecurity should be investigated because these might be the significantly associated factors with anemia in Yemen.

Acknowledgements

We thank the medical staff at the maternal clinics in Sana’a, Yemen, for their collaboration and support.

Conflict of Interest

This work does not include any conflicts of interest.

References

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“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

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Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

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Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

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Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

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Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

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Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

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Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

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Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

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Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

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Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

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Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

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Zhao Jia

Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."

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Thomas Urban

I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.

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Cristina Berriozabal

To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.

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Dr Tewodros Kassahun Tarekegn

"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".

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Dr Shweta Tiwari

I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.

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Dr Farooq Wandroo

Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.

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Dr Anyuta Ivanova

We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.

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Dr David Vinyes

My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.

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Gertraud Teuchert-Noodt

To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina

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Dr Elvira Farina