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Review Article | DOI: https://doi.org/10.31579/2690-1919/566
1State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious diseases, Wuhan, 430072, China.
2Tianjin Second People's Hospital, Tianjin 300100, China.
3Department of Clinical Immunology, School of Medical Laboratory, Tianjin Medical University, Tianjin 300203, China.
4Beijing Mic Vic Biotech Co., Ltd., Beijing 101200, China.
*These authors contributed equally to this work.
*Corresponding Author: Ma Ping, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious diseases, Wuhan,430072, China.
Citation: Yu Fangfang, Hu Yue, Yang Xiaohui, Josh Z. Lee, Ma Ping, (2025), A Review of the Current Status and Development Trends of Monkeypox POCT Detection, J Clinical Research and Reports, 20(5); DOI:10.31579/2690-1919/566
Copyright: © 2025, Ma Ping. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 04 August 2025 | Accepted: 15 August 2025 | Published: 21 August 2025
Keywords: monkeypox; poct detection; rapid detection; public health; pathogenicity
Monkeypox, a zoonotic orthopoxvirus first identified in 1958, re-emerged in 2022 as a global health crisis, with over 84,000 cases reported across 110 countries. This unprecedented outbreak underscored the virus’s capacity for human-to-human transmission and its potential to exploit gaps in diagnostic preparedness. Historically confined to Central and West Africa, monkeypox’s spread to non-endemic regions revealed vulnerabilities in healthcare systems, particularly in distinguishing it from other rash-inducing illnesses (e.g., chickenpox, herpes) and in delivering equitable testing access. Current diagnostic gold standards, such as PCR, offer high sensitivity but remain centralized and resource-intensive, leaving low-income regions underserved. Emerging technologies, including microfluidic devices, CRISPR-based platforms, isothermal amplification, and AI-driven genomic surveillance, promise to revolutionize point-of-care testing and outbreak tracking. This review synthesizes the virology, epidemiology, and transmission dynamics of monkeypox, critically evaluates existing diagnostic frameworks, and explores innovations poised to address persistent challenges. By situating the 2022 and 2024 outbreaks within the broader context of persistent challenges presented by unpredictable zoonotic threats, this analysis underscores the critical need for scalable, accessible diagnostics to manage emerging risks and advance equitable pandemic preparedness worldwide.
Monkeypox, a viral disease caused by the monkeypox virus (MPXV), has garnered significant global attention due to its recent outbreaks in non-endemic regions. Historically, monkeypox was primarily confined to Central and West Africa, where it was endemic among certain animal populations. However, the landscape of this disease has changed dramatically in recent years, particularly following the resurgence of cases in 2022, which prompted the World Health Organization (WHO) to declare it a Public Health Emergency of International Concern. The clinical presentation of monkeypox is similar to smallpox, characterized by fever, lymphadenopathy, and a distinctive rash that progresses through various stages. The disease is transmitted via direct contact with infected individuals or animals, as well as through contaminated materials, which has raised concerns about its potential for human-to-human transmission and the implications for public health on a global scale[1–4].
The expansion of monkeypox beyond its traditional endemic regions highlights the urgent need for effective diagnostic tools to facilitate timely identification and management of cases. Current diagnostic methods, such as real-time quantitative polymerase chain reaction (qPCR), are considered the gold standard for detecting MPXV. However, these methods often require specialized laboratory facilities, equipment and trained personnel, which may not be readily available in resource-limited settings. As a result, there is a pressing demand for point-of-care testing (POCT) solutions that can provide rapid, sensitive, and specific detection of monkeypox. POCT technologies have gained traction due to their portability and ease of use, making them ideal for deployment in various healthcare settings, particularly in response to outbreaks[5, 6].
Recent advancements in POCT for monkeypox and infectious disease detection have shown promising results, demonstrating the potential to revolutionize the management of this disease. Novel diagnostic approaches, such as CRISPR-based assays, lateral flow immunoassays, and microfluidic devices, have been developed to enhance the sensitivity and specificity of monkeypox detection. For instance, a CRISPR-Cas12a-based detection system targeting the MPXV A27L gene has achieved a remarkable detection limit, enabling rapid diagnosis directly from clinical samples[7]. Additionally, the development of affordable microfluidic devices holds great promise for improving the accessibility of monkeypox testing, particularly in regions with limited healthcare infrastructure[8, 9].
The emergence of monkeypox in non-endemic countries underscores the importance of developing robust surveillance systems and rapid response strategies. Effective monitoring and control of monkeypox outbreaks necessitate not only the availability of reliable diagnostic tools but also the implementation of public health measures aimed at reducing transmission. This includes vaccination campaigns, contact tracing, and public awareness initiatives to educate communities about the risks associated with monkeypox and the importance of seeking medical attention when symptoms arise[10]. Furthermore, ongoing research into the epidemiology and transmission dynamics of monkeypox will be crucial for informing future prevention and control strategies.
In conclusion, the recent resurgence of monkeypox has highlighted critical gaps in pandemic preparedness, including the need for equitable access to effective diagnostics. POCT technologies represent a vital component of the response to monkeypox, offering the potential for rapid and accurate detection in a wide range of healthcare settings. The re-emergence of MPXV underscores the interconnectedness of human, animal, and environmental health, as researchers continue to explore and refine these diagnostic approaches, it is essential to integrate them into broader public health strategies to mitigate future zoonotic spillover and address systemic vulnerabilities in global surveillance[11]. Here, we summarize and explore the most recent POCT technologies that can offer de-centralized, accessible, and low-cost diagnostics for use in the management of future outbreaks to improve global response to monkeypox.
2.1 Pathogenic Characteristics of Monkeypox Virus
2.1.1 Virus Classification and Structure
Monkeypox virus (MPXV) is a member of the Orthopoxvirus genus within the Poxviridae family. This classification places it in close relation to other notable viruses such as variola virus (the causative agent of smallpox), vaccinia virus (used in the smallpox vaccine), and cowpox virus. MPXV is characterized as a linear double-stranded DNA virus with a relatively large genome, which allows for a variety of genetic mutations and adaptations. The virus exhibits a brick-shaped morphology, typical of poxviruses, and is enveloped by a lipid membrane that contains various proteins essential for its infectivity and immune evasion[2].
The structural components of MPXV include the viral core, which houses the genetic material, surrounded by a proteinaceous layer known as the lateral body, and a lipid envelope. This structure is crucial for the virus's ability to enter host cells and evade the host immune response. The envelope contains glycoproteins that facilitate attachment to host cell receptors, initiating the infection process. Understanding the structural biology of MPXV is vital for developing targeted antiviral therapies and vaccines, as well as for enhancing diagnostic methods[12].
2.1.2 Transmission Routes and Epidemiology
Historically, monkeypox has been endemic to regions of Central and West Africa, primarily transmitted to humans through zoonotic spillover from infected animals, particularly rodents and primates. The recent global outbreak, which began in 2022, has highlighted a shift in transmission dynamics, with increased human-to-human transmission observed, particularly among men who have sex with men (MSM) [3, 13]. This change in epidemiology underscores the virus's adaptability and raises concerns about its potential to establish endemicity in non-traditional regions.
Transmission occurs through direct contact with infectious lesions, bodily fluids, or respiratory droplets from an infected individual. The virus can also be transmitted via contaminated objects, such as bedding or clothing, further complicating control measures. The incubation period for MPXV ranges from 5 to 21 days, with symptoms typically including fever, lymphadenopathy, and a characteristic rash that progresses through various stages[14]. The 2022 outbreak has seen confirmed cases reported in 112 countries, emphasizing the need for robust surveillance and public health interventions to mitigate further spread[3, 15].
2.1.3 Clinical Manifestations and Diagnostic Challenges
The clinical presentation of monkeypox can vary significantly, complicating diagnosis. Initial symptoms often resemble those of other viral infections, including fever, malaise, and lymphadenopathy. The distinctive rash typically appears 1 to 3 days after the onset of fever, progressing from macules to papules, vesicles, and pustules before crusting over[16]. Notably, the rash can present atypically, particularly in immunocompromised individuals, leading to misdiagnosis or delayed treatment[14].
Diagnostic challenges arise due to the overlap in clinical features with other conditions, such as varicella (chickenpox) and herpes simplex virus infections. Laboratory confirmation is essential, with real-time polymerase chain reaction (RT-PCR) being the gold standard for MPXV detection. However, the requirement for specialized equipment and trained personnel can limit access to timely diagnosis, particularly in resource-limited settings[17]. Emerging diagnostic technologies, including CRISPR-based assays, microfluidics, and point-of-care testing (POCT) methods, show promise in enhancing the speed and accuracy of MPXV detection, potentially addressing some of these challenges[7, 18].
In summary, the pathogenic characteristics of monkeypox virus encompass its classification, structural biology, transmission dynamics, and clinical manifestations. The ongoing global outbreak necessitates a comprehensive understanding of these aspects to inform public health strategies, improve diagnostic capabilities, and develop effective therapeutic interventions.
2.2 Overview of POCT Testing Technology
2.2.1 Definition and Advantages of POCT Technology
Point-of-care testing (POCT) refers to diagnostic tests performed at or near the site of patient care, allowing for immediate results and timely clinical decision-making. This approach is highly beneficial in various healthcare settings, including emergency departments, outpatient clinics, and even at home. The primary advantages of POCT technology include rapid turnaround times, ease of utilization, reduced need for laboratory infrastructure, and improved patient management through immediate feedback. Studies have shown that POCT can significantly enhance the efficiency of healthcare delivery by providing timely diagnostic information, which is crucial for managing both acute and chronic diseases alike. Furthermore, POCT devices are typically designed to be user-friendly, allowing healthcare professionals and patients to perform tests with minimal training. This accessibility is especially important in resource-limited settings where traditional laboratory services may be unavailable or delayed. POCT can lead to improved patient outcomes by facilitating quicker treatment decisions and reducing the time to diagnosis, ultimately contributing to better disease management and control[19, 20]
Moreover, the integration of advanced technologies, such as mobile applications and telemedicine, with POCT has further enhanced its capabilities. For instance, smartphone-based POCT devices can transmit test results directly to healthcare providers, enabling remote monitoring and consultations. This feature is particularly advantageous in managing infectious diseases, as it allows for real-time tracking of disease outbreaks and patient health status[21–23]. The potential for POCT to bridge the gap between patients and healthcare providers is immense, especially in the context of global health challenges such as the COVID-19 pandemic, where rapid testing and isolation measures are critical[12].
2.2.2 Commonly Used POCT Devices and Methods
A variety of POCT devices and methods are currently employed across different medical fields, each designed to address specific diagnostic needs. Commonly used POCT devices include lateral flow assays (LFAs), glucose meters, and molecular diagnostic platforms. LFAs are particularly popular due to their simplicity and rapid results, making them ideal for testing infectious diseases like HIV, malaria, and more recently, monkeypox[17, 20]. These tests typically involve a sample being applied to a test strip that contains specific antibodies or antigens, allowing for visual interpretation of results within minutes.
Glucose meters are among the most widely utilized POCT devices, especially for diabetes management. Recent advancements have led to the development of personal glucose meters that can detect non-glucose targets, demonstrating the versatility of these devices[7]. Additionally, molecular diagnostic methods, such as polymerase chain reaction (PCR) and CRISPR-based assays coupled with portable devices[18], are increasingly being adapted for POCT applications. These methods offer high sensitivity and specificity, making them suitable for detecting various pathogens, including viral and bacterial infections[12, 24].
Emerging technologies, such as microfluidic devices and wearable sensors, are also gaining traction in the POCT landscape. Microfluidic devices, often referred to as "lab-on-a-chip" systems, enable multiple tests to be conducted simultaneously on a single chip, significantly reducing the time and resources required for testing[8, 9, 25]. Wearable sensors, on the other hand, allow for continuous monitoring of health parameters, providing real-time data that can be crucial for managing chronic conditions[26]. The integration of these advanced technologies into POCT not only enhances diagnostic capabilities but also contributes to personalized medicine by allowing for tailored treatment approaches based on individual patient data[27].
In summary, POCT technology encompasses a diverse range of devices and methods that provide rapid, accurate, and accessible diagnostic solutions. The ongoing advancements in this field hold great promise for improving healthcare delivery and patient outcomes across various medical domains.
2.3 Current POCT Detection Methods for Monkeypox
The emergence of monkeypox as a significant global health concern necessitates the development of effective point-of-care testing (POCT) methods. These methods are essential for rapid diagnosis, particularly in resource-limited settings where traditional laboratory facilities may not be available[28]. Current POCT methods for monkeypox focus on various aspects, including sample collection and processing techniques, detection principles and workflows, and a comparative analysis of existing market products.
2.3.1 Sample Collection and Processing Techniques
Sample collection and processing are critical steps in the accurate detection of the monkeypox virus (MPXV). The choice of sample type can significantly impact the sensitivity and specificity of the diagnostic tests. Recent studies have highlighted various sample types, including skin lesions, saliva, and oropharyngeal swabs, as viable options for MPXV detection. For instance, herpes fluid and saliva have been identified as particularly suitable sources for testing, demonstrating a high correlation with qPCR results, which is considered the gold standard for MPXV detection[12].
The integration of innovative sample processing techniques also enhances the efficiency of POCT. For example, the use of magnetic bead-based nucleic acid extraction methods has been shown to improve the sensitivity and specificity of loop-mediated isothermal amplification (LAMP) assays, achieving sample-to-answer detection within one hour[29, 30]. Additionally, advancements in portable devices enable rapid and accurate sample processing, essential for effective outbreak management in field settings[17]. The development of integrated devices that combine sample collection, processing, and detection capabilities streamlines the diagnostic workflow, making it more accessible for healthcare providers in various settings[6, 17, 24].
2.3.2 Detection Principles and Workflows
The detection of monkeypox virus employs various principles and methodologies, each with distinct advantages and limitations. The most common techniques include polymerase chain reaction (PCR), CRISPR-based assays, and lateral flow assays (LFAs). PCR remains the gold standard due to its high sensitivity and specificity; however, it requires specialized equipment and trained personnel, which may not be available in all healthcare settings[12].
Emerging technologies, such as CRISPR-Cas12a-based detection systems, have shown promise in providing rapid and accurate results. These systems can achieve detection limits as low as 10 aM and deliver results in under 40 minutes, making them suitable for POCT applications[12]. Moreover, the integration of CRISPR technology with lateral flow assays allows for visual result interpretation, enhancing usability in low-resource environments[24].
LAMP assays represent another innovative approach, providing rapid results without the need for complex instrumentation. The development of colorimetric LAMP assays has demonstrated high sensitivity and specificity, with the ability to visually detect MPXV within one hour[29]. These assays can be particularly beneficial in emergency settings where timely diagnosis is crucial for outbreak control.
These innovations collectively address critical barriers in POCT, making advanced diagnostics more accessible, reliable, and efficient for global health applications.
2.3.3 Existing Products and Comparison
The market for monkeypox detection products is rapidly evolving, with several innovative solutions emerging to address the urgent need for effective diagnostics. A comparative analysis of existing products reveals a range of performance characteristics, including sensitivity, specificity, and ease of use. For instance, lateral flow assays based on upconversion nanoparticles have been developed, offering dual-mode detection capabilities with rapid readout times of less than 8 minutes[20]. These assays exhibit lower limits of detection compared to traditional methods, making them highly competitive in the POCT landscape.
Another notable product is the DMSO-enhanced one-pot HDA-CRISPR/Cas12a biosensor, which achieves a limit of detection of 10 fM and demonstrates high specificity in distinguishing MPXV from closely related orthopoxviruses[24]. The ability to provide rapid results while maintaining high sensitivity positions this product as a valuable tool for healthcare providers.
In addition to these advancements, the development of multiplexed biosensing platforms is gaining traction. These platforms can simultaneously detect multiple pathogens, including MPXV, which is particularly advantageous in the context of co-infections and emerging infectious diseases[31]. The integration of various detection technologies into a single platform enhances diagnostic capabilities and facilitates comprehensive patient management.
In conclusion, the current landscape of POCT methods for monkeypox detection is characterized by rapid advancements in sample collection techniques, innovative detection principles, and a diverse array of market products. As the global health community continues to address the challenges posed by monkeypox, these developments are crucial for enhancing diagnostic capabilities and improving outbreak response efforts. Continued research and investment in POCT technologies will play a vital role in controlling the spread of monkeypox and other emerging infectious diseases.
2.4 Application of POCT Technology in Monkeypox Outbreak Management2.4.1 Early screening and diagnosis
Point-of-care testing (POCT) technology has emerged as a critical tool in the early screening and diagnosis of monkeypox virus (MPXV) infections, particularly in the context of recent outbreaks. The need for rapid and accurate diagnostic methods is underscored by the zoonotic nature of monkeypox and its potential for human-to-human transmission, especially in non-endemic regions. Traditional diagnostic methods, such as quantitative polymerase chain reaction (qPCR), while highly sensitive, require specialized laboratory facilities and trained personnel, which can delay timely diagnosis and treatment. In contrast, POCT offers a more accessible and efficient alternative. For instance, recent advancements have led to the development of a CRISPR-Cas12a-based detection system targeting the MPXV A27L gene, achieving a detection limit as low as 10 aM and providing results in under 40 minutes[7]. This rapid turnaround is crucial for initiating appropriate public health responses, especially during outbreaks.
Moreover, innovative approaches such as the use of upconversion nanoparticles-based lateral flow assays (UCNPs-LFA) have demonstrated the capability for both qualitative and quantitative detection of MPXV with a much lower limit of detection compared to existing POCT methods. This dual-mode detection system, which can be integrated with smartphones for real-time results, exemplifies the potential of POCT to enhance early diagnosis in resource-limited settings[20]. The integration of these technologies not only facilitates early identification of infected individuals but also aids in distinguishing between different clades of MPXV, which is essential given their varying transmissibility and clinical manifestations.
The ability to conduct testing at the point of care significantly reduces the time to diagnosis, thereby enabling quicker isolation of cases and implementation of control measures. Studies have shown that the use of POCT can lead to improved management outcomes in infectious diseases, as it empowers healthcare providers to make informed decisions based on immediate results[24]. Furthermore, the development of user-friendly devices that do not require extensive training can democratize access to testing, particularly in underserved regions where healthcare infrastructure may be lacking.
In conclusion, the application of POCT technology in the early screening and diagnosis of monkeypox is pivotal in managing outbreaks effectively. By facilitating rapid diagnosis, these technologies enable timely public health interventions, thereby mitigating the spread of the virus and enhancing overall epidemic response strategies.
2.4.2 Epidemic surveillance and containment
The role of point-of-care testing (POCT) technology extends beyond early diagnosis to encompass epidemic monitoring and control of monkeypox virus (MPXV) outbreaks. Effective surveillance systems are essential for tracking the spread of infectious diseases, and POCT provides a valuable tool for real-time monitoring of MPXV transmission dynamics. The integration of POCT into existing public health frameworks can enhance the ability to respond swiftly to emerging outbreaks, particularly in non-endemic regions where healthcare systems may be less prepared.
One of the key advantages of POCT is its capacity to facilitate widespread testing in community settings, allowing for the rapid identification of cases. This is particularly important in the context of monkeypox, where early detection can significantly impact transmission rates. For example, a study demonstrated that utilizing a rapid lateral flow assay for MPXV detection enabled healthcare providers to identify cases quickly, leading to timely isolation and treatment of infected individuals[17]. This rapid response is crucial in preventing further spread, especially in densely populated areas or regions experiencing outbreaks.
Moreover, POCT technologies can be utilized for continuous monitoring of high-risk populations, enabling public health officials to identify potential hotspots for transmission. By implementing regular screening protocols in these populations, health authorities can gather valuable epidemiological data that informs public health strategies. For instance, the use of mobile health applications linked to POCT devices can facilitate real-time data collection and analysis, allowing for the monitoring of trends in MPXV cases and the effectiveness of control measures[32].
The ability to conduct on-site testing also reduces the burden on centralized laboratories, which may become overwhelmed during outbreaks. This decentralization of testing not only improves the efficiency of the public health response but also enhances the accessibility of diagnostic services for communities[28]. Furthermore, the incorporation of POCT into surveillance systems can lead to improved compliance with testing protocols, as patients are more likely to participate in testing that is convenient and readily available.
The application of POCT technology in epidemic monitoring and control of monkeypox is instrumental in enhancing public health responses. By enabling rapid case identification and continuous surveillance, POCT supports the implementation of effective control measures, ultimately contributing to the containment of outbreaks and the protection of public health.
2.4.3 Clinical management and patient follow-up
Point-of-care testing (POCT) technology plays a significant role in the clinical management and follow-up of patients diagnosed with monkeypox virus (MPXV) infections. The integration of POCT into clinical workflows not only enhances the efficiency of patient management but also improves patient outcomes through timely interventions and monitoring. As monkeypox cases continue to rise globally, effective clinical management strategies are essential to mitigate the impact of the disease.
One of the primary benefits of POCT in clinical management is its ability to provide immediate diagnostic results, which facilitates prompt decision-making regarding treatment and patient care. For instance, the rapid detection of MPXV using POCT technologies allows healthcare providers to initiate appropriate antiviral therapy and supportive care without delay[33]. This is particularly crucial in managing severe cases where timely intervention can significantly alter the clinical course and reduce the risk of complications.
Furthermore, POCT can enhance patient follow-up by enabling continuous monitoring of viral load and treatment response. For example, the use of CRISPR-based assays for MPXV detection allows clinicians to assess the effectiveness of antiviral treatments in real time, guiding adjustments to therapy as needed[24]. This dynamic approach to patient management ensures that individuals receive personalized care tailored to their specific clinical needs.
In addition to direct patient management, POCT facilitates better communication and engagement with patients[34]. By providing accessible testing options, patients are more likely to participate in follow-up care and adhere to treatment protocols. This is particularly important in the context of monkeypox, where ongoing monitoring is essential for detecting potential complications or relapses. Studies have shown that patients who are actively involved in their care through regular follow-up and monitoring exhibit improved adherence to treatment regimens and better overall health outcomes[3].
Moreover, the integration of POCT into clinical management can streamline healthcare workflows, reducing the burden on healthcare providers and allowing them to focus on delivering high-quality care. By minimizing the need for laboratory-based testing and enabling on-site diagnostics, POCT can enhance the efficiency of clinical operations, particularly in resource-limited settings where healthcare infrastructure may be challenged[35].
In conclusion, the application of POCT technology in the clinical management and follow-up of monkeypox patients is crucial for improving patient outcomes and enhancing the overall quality of care. By facilitating rapid diagnosis, continuous monitoring, and patient engagement, POCT supports effective management strategies that are essential for addressing the challenges posed by monkeypox outbreaks.
2.5 Future Development Directions and Challenges
2.5.1 Improvement and Innovation of Detection Methods
The ongoing global health challenges posed by diseases like monkeypox underscore the urgent need for innovative and improved detection methods. Traditional diagnostic techniques, such as quantitative polymerase chain reaction (qPCR), while effective, often require specialized personnel and expensive equipment, making them less accessible, especially in resource-limited settings[12]. Recent advancements in point-of-care testing (POCT) have shown promise in addressing these limitations by providing rapid, on-site diagnostic capabilities. For instance, the development of a CRISPR-Cas12a-based detection system targeting specific genes of the monkeypox virus has demonstrated high sensitivity and specificity, achieving detection limits as low as 10 attomolar[7]. Furthermore, innovations such as microfluidic chip assays[8], coupled with innovations in interferometry reflectance imaging[9] and colorimetric loop-mediated isothermal amplification (LAMP) systems have been integrated into POCT frameworks, allowing for quick and visual results that can be interpreted without specialized training, while dramatically improving in sensitivity[29].
The introduction microfluidic technologies have enhanced molecular and antigen-based POCT by streamlining workflows and enhancing performance. By integrating sample preparation, reagent handling, and detection into miniaturized, automated systems, microfluidics significantly reduces manual steps, enabling even non-specialized users to conduct complex assays with minimal training[8, 9, 21, 36, 37]. This simplification, coupled with reduced reagent consumption and scalable manufacturing, drives down costs while maintaining high precision. Furthermore, microfluidic platforms enhance sensitivity through precise control of nanoliter-scale reactions and improve specificity via advanced surface functionalization or microchannel designs that minimize cross-reactivity. In the case of antigen-based detection methods, it was able to achieve picogram level sensitivity[8, 21].
Moreover, the incorporation of digital technologies into diagnostic processes has opened new avenues for enhancing detection methods. For example, the use of artificial intelligence (AI) and machine learning algorithms in image recognition tasks for diagnosing monkeypox skin lesions has shown significant potential[38]. These technologies can improve diagnostic accuracy and efficiency, allowing for faster identification of cases and better management of outbreaks. The challenge remains to ensure that these innovative methods are not only effective but also scalable and affordable for widespread use, particularly in low-resource settings where the burden of such diseases is often the highest.
2.5.2 Automation of Data Management and Result Interpretation
As diagnostic technologies evolve, so too does the need for efficient data management and result interpretation systems. The integration of automated data management systems can significantly enhance the speed and accuracy of disease detection and monitoring. Current practices often rely on manual data entry and analysis, which can lead to errors and delays in reporting critical health information. Automated systems can streamline these processes by utilizing electronic health records (EHRs) and real-time data analytics to capture and analyze diagnostic results promptly[39].
The development of user-friendly interfaces that allow healthcare providers to easily interpret results is also crucial. For instance, the incorporation of visual aids and decision-support systems can help clinicians make informed decisions based on diagnostic data, ultimately improving patient outcomes[40]. Additionally, the use of machine learning algorithms to analyze large datasets can identify trends and patterns in disease spread, facilitating proactive public health interventions[41].
However, the implementation of such automated systems is not without challenges. Issues related to data privacy, security, and interoperability between different health information systems must be addressed to ensure that these technologies can be effectively integrated into existing healthcare infrastructures. Furthermore, training healthcare professionals to utilize these automated systems effectively is essential to maximize their benefits and ensure accurate interpretation of results.
2.5.3 Public Acceptance and Education
Public acceptance of new diagnostic methods and vaccines is a critical factor in the success of public health initiatives. The recent monkeypox outbreaks have highlighted the importance of effective communication and education strategies to enhance public understanding of the disease and its prevention. Surveys have shown that knowledge levels regarding monkeypox among the general population are often inadequate, which can lead to increased anxiety and vaccine hesitancy[42].
Educational campaigns that provide clear, accessible information about monkeypox, its transmission, and the benefits of vaccination are essential. For example, targeted outreach to high-risk populations, such as men who have sex with men (MSM), can help increase awareness and acceptance of vaccination[43]. Furthermore, leveraging social media and community engagement strategies can effectively disseminate information and address misconceptions about the disease[44].
In addition to education, addressing the psychological and social factors that influence vaccine acceptance is crucial. Factors such as perceived susceptibility to infection, previous experiences with healthcare systems, and socio-economic status can significantly impact individuals' willingness to accept vaccines[40]. Tailoring educational materials to address these factors and fostering trust in healthcare providers can enhance public confidence in vaccination efforts.
Ultimately, a multifaceted approach that combines education, community engagement, and targeted communication strategies is essential to improve public acceptance of new diagnostic methods and vaccines. By empowering individuals with knowledge and addressing their concerns, public health authorities can facilitate a more effective response to emerging infectious diseases like monkeypox.
The evolution of POCT has been marked by significant technological advancements, which have improved the speed, accuracy, and accessibility of diagnostic testing. These improvements are particularly crucial in the context of monkeypox, where timely identification of cases can drastically influence outbreak containment strategies. The ability to conduct rapid tests at the point of care enables healthcare providers to make informed decisions without delay, ultimately reducing transmission rates and improving patient outcomes. Moreover, POCT can play a pivotal role in epidemiological research by facilitating the collection of data in real-time, which is essential for tracking the spread of the disease and identifying potential hotspots.
However, the integration of POCT into monkeypox management is not without its challenges. For instance, while the sensitivity and specificity of POCT methods have improved, variability in test performance across different settings can undermine their reliability. Therefore, rigorous validation and standardization of POCT devices are imperative to ensure consistent results, especially in diverse geographical and clinical contexts.
Additionally, the successful implementation of POCT relies heavily on the education and training of healthcare personnel. It is crucial that practitioners are well-versed in the operational aspects of these testing modalities, including sample collection, interpretation of results, and subsequent clinical decision-making. Furthermore, public awareness campaigns are necessary to inform communities about the availability and importance of POCT in the context of monkeypox. Balancing the educational needs with the rapid deployment of these technologies requires a concerted and multidisciplinary effort from public health authorities, healthcare institutions, professionals, and educational organizations. This collaborative framework can also foster the development of innovative solutions that address both the technical and logistical challenges associated with POCT implementation.
In conclusion, while the promise of POCT in enhancing monkeypox detection and management is evident, realizing its full potential will require a nuanced understanding of the various research perspectives and findings. The path forward necessitates a delicate balance between leveraging technological advancements and addressing the inherent challenges of implementation. By fostering a collaborative environment that encourages ongoing research, education, and dialogue among stakeholders, we can pave the way for a more effective and responsive approach to managing monkeypox and similar infectious diseases in the future. Ultimately, the goal is to harness the power of POCT to not only combat current outbreaks but also to prepare for future public health challenges, thereby safeguarding communities and enhancing global health security.
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As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
